Navigation Links
Dartmouth researchers get personal with genetics
Date:9/15/2009

HANOVER, NH Two recent studies by Dartmouth researchers use individual genetic data to reveal the powers and limits of our current understanding of how the genome influences human health and what genes can reveal about the ancestry of the people of New Hampshire.

Published in the Sept. 11 issue of the American Journal of Human Genetics, Dartmouth Professor Jason Moore and Vanderbilt Professor Scott Williams analyzed how personal genetic testing companies are using still-nascent genome data to judge the health of their customers. Their paper is titled "Epistasis and its Implications for Personal Genetics."

People can now buy inexpensive kits, submit a DNA sample (often a swab from the inside of a cheek or a little bit of saliva), and receive data about their susceptibility to a number of gene-influenced ailments, such as prostate cancer, Alzheimer's, or type II diabetes. Moore and Williams argue that our knowledge of the human genome and its relationship to human health, while growing by leaps and bounds, is still in its infancy.

"The relationship between health and genetics is very complex," says Moore, professor of genetics and of community and family medicine at Dartmouth Medical School (DMS). "It's often a combination of multiple genes and multiple environmental factors that work together to increase or decrease your risk of disease. I don't think the knowledge base is sufficient to put genetics in the hands of the public quite yet." Moore is also the Frank Lane Research Scholar in Computational Genetics and Director of Bioinformatics at DMS

The authors admit that genetic research is progressing, and they cite the example of the discovery of the BRCA1 and BRCA2 genes and their role in breast cancer. However, the authors caution that, while there is no question these genes are involved in breast cancer, the underlying mechanisms behind the genetic risk are still being worked out.

"There is a perception
'/>"/>

Contact: Sue Knapp
sue.knapp@dartmouth.edu
603-646-3661
Dartmouth College
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Dartmouth researchers find new protein function
2. Dartmouth workshop sets research agenda for environmental mercury
3. Dartmouth awarded NSF grant for new polar sciences, engineering grad program
4. Dartmouth researchers identify an important gene for a healthy, nutritious plant
5. Dartmouth researchers discover gene signatures for scleroderma
6. Dartmouth researchers find the root of the evolutionary emergence of vertebrates
7. Dartmouth researchers alarmed by levels of mercury and arsenic in Chinese freshwater ecosystem
8. Dartmouth researchers show effects of low dose arsenic on development
9. Ecosystem researchers to hold science briefing for policymakers
10. UAB researchers looking for genetic predictors for suicide
11. Rice researchers seek better vaccine procedure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... at the Department of Energy,s Oak Ridge National ... by R&D Magazine in recognition of the year,s ... the tremendous value of our National Labs," said ... at the National Labs continues to help our ... scientific and technological innovations necessary to remain globally ...
(Date:7/11/2014)... Bone and Mineral Research awarded Michael F. Holick, PhD, ... the 2014 Louis V. Avioli Award. Holick, a professor ... known for revolutionizing the understanding of vitamin D and ... honors a member of the American Society for Bone ... and mineral basic research. It is named for ASBMR,s ...
(Date:7/11/2014)... Cell scientists have set a "mouse TRAP" to capture ... a recent study published in the Journal of ... a technique called TRAP to extract cellular and genetic ... by scientists at the Rockefeller Institute for Medical Research ... the protein-making machinery, or ribosomes, of the cell type ...
Breaking Biology News(10 mins):ORNL wins eight R&D 100s 2ORNL wins eight R&D 100s 3ORNL wins eight R&D 100s 4BUSM's Michael F. Holick receives American Society for Bone and Mineral Research award 2
... Scientists propose developing an environmentally-friendly fungal spray that would ... a critical growth stage. This spray will contain ... and will have no side-effects on non-target organisms and ... therefore provide a quick, safe and effective means for ...
... the Technion Israel Institute of Technology, the ... have recently identified genes responsible for the positive ... drug Copaxone®. These findings may contribute to the ... Copaxone® was the first original Israeli drug ...
... -- A new book by researchers at the ... the mouse demonstrates a surprising similarity between mice and humans. ... by a team from the Hebrew University Bone Laboratory consisting ... Hajbi-Yonissi and Dr. Yankel Gabet. Also participating in the writing ...
Cached Biology News:New hope for horse lovers as effective control for killer ragwort is proposed 2Israeli scientists identify: Genes that affect responses of multiple sclerosis patients to copaxone 2Of mice and men: similarities between skeletons of both 2
(Date:7/10/2014)... 10, 2014 OMICS Group’s 5th International ... 18-20 August, 2014 at Double Tree by Hilton Beijing, ... developments in Analytical & Bioanalytical research methods only to ... on this occasion, Dr. Srinubabu Gedela, MD of OMICS ... is a remarkable one in bringing a unique and ...
(Date:7/10/2014)... ST. PETERSBURG, Russia , July 10, 2014 /PRNewswire/ ... the Russian Federation Dmitry Medvedev , presented ... a biopharmaceutical company BIOCAD . The Company is ... the scope of MabNext project BIOCAD develops a number ... of cancer and autoimmune diseases. The ceremony took place ...
(Date:7/10/2014)... OAKS, Calif., July 10, 2014   Ceres, Inc ... and seed company, announced today financial results for the ... update on its business. Ceres reported that ... in product performance this growing season in Brazil, which ... affected the company,s sorghum evaluation areas for part of ...
(Date:7/10/2014)... journal PNAS (Proceedings of the National Academy of ... sleep deprivation have a significant effect on our metabolism. ... best time of day to test for diseases such ... effectively. , Researchers from the University of Surrey and ... between sleep deprivation, body clock disruption and metabolism, and ...
Breaking Biology Technology:A Critical Review of Analytical Techniques for Improved Living Standards 2A Critical Review of Analytical Techniques for Improved Living Standards 3A Critical Review of Analytical Techniques for Improved Living Standards 4Dmitry Medvedev Presented BIOCAD the First National "Industry" Award 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 3Ceres Announces Fiscal Third Quarter 2014 Financial Results 4Ceres Announces Fiscal Third Quarter 2014 Financial Results 5Ceres Announces Fiscal Third Quarter 2014 Financial Results 6Ceres Announces Fiscal Third Quarter 2014 Financial Results 7Ceres Announces Fiscal Third Quarter 2014 Financial Results 8Ceres Announces Fiscal Third Quarter 2014 Financial Results 9Time of day crucial to accurately test for diseases, new research finds 2
... 19 /PRNewswire-FirstCall/ - ARIUS Research Inc., (TSX:,ARI), a ... of,antibody therapeutics, today announced that David Young, MD, ... at the Chinese Global,Financial Forum. Dr. Young will ... will be available prior to and following his ...
... ... WEST HAVEN, Conn., Oct. 19 Dr. Heather Coyle ... Haven have,developed a new method for preparing certain skeletal remains ... the,research the group is doing for the Smithsonian Institution. Obtaining ...
... Therapeutics Inc., a,Nutritional Therapeutics Innovation Company, today announced ... Wakeman as President. "Pilot has always had ... and dietary supplement areas with over 60 issued ... potential to rapidly move our,world class technologies and ...
Cached Biology Technology:ARIUS to present at Chinese Global Financial Forum 2800-Year-Old Mummies Aid Current Cold Cases: 2Pilot Therapeutics Announces New Executive Team with Extensive Experience Creating New Health and Nutrition Businesses 2
Special grade: for molecular biology Density: 1.000 g/mL (20 C)...
... cleaning agent for removing RNase ... and pipettors. It is ... contamination from microcentrifuge tubes without ... Zap (R) is ...
Matrix for protein MALDI-MS...
... number is a new ... easily match Cornings product ... availability yet, please order ... number (Z36,327-8) or contact ...
Biology Products: