Navigation Links
Dartmouth researchers find promising results with local hyperthermia of tumors
Date:3/4/2014

rature at a uniform 43 degrees C for as long as desired," said Fiering. "This precise control was the key to optimal immune stimulation."

The experiment included mouse colon and, melanoma cancers. Tumors responded to the heat by growing more slowly or disappearing completely. A higher temperature was better at eliminating primary tumors that were heat treated, but did not activate the immune system as well to find and attack metastatic tumors. Treatment of larger primary tumors generated a stronger immune response.

In the effort to develop better cancer treatments, the challenge is to find ways to cure metastatic disease. "The use of the immune system through cancer immunotherapy is a very exciting field currently and promises to contribute significantly to elimination of metastatic tumors," said Fiering. "The approach demonstrated is a good new option to be combined with other immunotherapy strategies for cancer therapy."

Standard cancer care involves surgery, but surgeons have few tools to guarantee the removal of every cancer cell, especially when there is unrecognized metastases in other anatomic locations. An approach like local hyperthermia one day might be used to kick start the immune system to ward off any cancer cells not removed by surgery to increase the chances of treatment success.


'/>"/>

Contact: Donna Dubuc
donna.M.Dubuc@Dartmouth.edu
603-653-3615
The Geisel School of Medicine at Dartmouth
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Dartmouth-led research shows temperature, not snowfall, driving tropical glacier size
2. Dartmouth study shows US Southwest irrigation system facing decline after 4 centuries
3. Dartmouth researchers develop new tool to identify genetic risk factors
4. Dartmouth-led team gets $8 million grant to research arsenic in children
5. Dartmouth-led study shows diet alone can be significant source of arsenic
6. Dartmouth-led team discovers how plants avoid sunburn
7. Dartmouth researchers find there is no single sexy chin
8. Dartmouth researchers invent real time secondhand smoke sensor
9. Dartmouth neuroscientist finds free will has neural basis
10. Dartmouth research offers new control strategies for bipolar bark beetles
11. Mercury releases contaminate ocean fish: Dartmouth-led effort publishes major findings
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Dartmouth researchers find promising results with local hyperthermia of tumors
(Date:9/16/2014)... impact that spelled doom for the dinosaurs 66 million ... to a much greater extent than their deciduous peers, ... results are published in the journal PLOS Biology ... trove of thousands of fossilized leaves of angiosperms ... able to reconstruct the ecology of a diverse plant ...
(Date:9/16/2014)... a new football season and another commercial cargo flight ... spacecraft is scheduled to blast off to the orbital ... company,s fourth contracted mission to the complex. , Included ... research investigations sponsored by the Center for the Advancement ... managing the U.S. National Laboratory on the space station, ...
(Date:9/16/2014)... Keystone XL pipeline (KXL) would likely increase oil sands ... surveyed by the non-profit organization Near Zero. The results ... Impact," and includes both supporters and opponents of the ... sands could lead to significantly higher greenhouse gas emissions, ... respond. , "This report examines three main scenarios ...
Breaking Biology News(10 mins):Meteorite that doomed dinosaurs remade forests 2Meteorite that doomed dinosaurs remade forests 3Meteorite that doomed dinosaurs remade forests 4CASIS research set for launch aboard SpaceX mission to space station 2CASIS research set for launch aboard SpaceX mission to space station 3Keystone XL would likely raise oil sands production and greenhouse gas emissions 2
... has identified a genetic variant that substantially increases the ... populations. The study, published by Cell Press on August ... , associates a deletion on chromosome 3 with increased ... that affects 1% of the world population. Characterized by ...
... scientists have been able to measure the amount of water that ... result -- 285 billion metric tons, or 285 cubic kilometers of ... over half the volume of Lake Erie, which is the world,s ... of the water flowing through the Amazon River every year, and ...
... Swine Flu. Rabies. These are emerging infectious diseases where ... another and now infect humans. This is a phenomenon ... to determine what drives it. Gary McCracken, a ... head in Ecology and Evolutionary Biology, is one of ...
Cached Biology News:Large risk schizophrenia marker revealed 2First satellite measurement of water volume in Amazon floodplain 2First satellite measurement of water volume in Amazon floodplain 3UT professor uncovers clues into how viruses jump from hosts 2
(Date:9/16/2014)... According to Jeff Howell, Partner of Nidea ... new development in Downtown Toronto is expanding at a ... 755 storeys of new development last week (including three ... dominating the Toronto skyline for the foreseeable future in ... for new development. , As the Toronto city council ...
(Date:9/15/2014)... 16, 2014 Cancer Immunotherapy ... Adoptive T-cell Therapies is a new market research ... the three principal types of therapeutics that have ... in cancer immunotherapy (which is often called "immuno-oncology") ... and Adoptive cellular immunotherapy. , The regular ...
(Date:9/15/2014)... fast when a patient has sepsis, a life-threatening condition ... blood -- often too fast for antibiotics to help. ... developed by a team at Harvard,s Wyss Institute for ... treat sepsis. , "Even with the best current ... at least 30 percent of the time," said Mike ...
(Date:9/15/2014)... , Sept. 15, 2014 Zymo ... viral transport solution for safe ambient temperature storage ... molecular testing. Importantly, the infectivity of agents in such ... maintaining the integrity of the viral nucleic acids ... the recent Ebola epidemic in West ...
Breaking Biology Technology:ITRA Global Reports Downtown Toronto Real Estate Development is in High Gear 2ITRA Global Reports Downtown Toronto Real Estate Development is in High Gear 3Cancer Immunotherapy Market: Immune Checkpoint Inhibitors, Cancer Vaccines, and Adoptive T-cell Therapies 2Cancer Immunotherapy Market: Immune Checkpoint Inhibitors, Cancer Vaccines, and Adoptive T-cell Therapies 3Cancer Immunotherapy Market: Immune Checkpoint Inhibitors, Cancer Vaccines, and Adoptive T-cell Therapies 4Cancer Immunotherapy Market: Immune Checkpoint Inhibitors, Cancer Vaccines, and Adoptive T-cell Therapies 5Blood-cleansing biospleen device developed for sepsis therapy 2Blood-cleansing biospleen device developed for sepsis therapy 3Blood-cleansing biospleen device developed for sepsis therapy 4Safe storage and transport of Ebola, Mers-CoV, and other viruses: Groundbreaking viral inactivation solution capable of preserving nucleic acids 2Safe storage and transport of Ebola, Mers-CoV, and other viruses: Groundbreaking viral inactivation solution capable of preserving nucleic acids 3
... 14 At the Board of Directors,meeting held ... of,$.115 per share. The dividend is payable on ... 31, 2007. About Sigma-Aldrich: Sigma-Aldrich is a ... and organic chemical products and kits,are used in ...
... Summertime equals fun for a lot of,folks. But ... typical,summer fare could also mean aggravating their sensitive ... IBS," has more on,what people with IBS can ... from,ruining their celebrations. Listen to this report ...
... 15 /PRNewswire-FirstCall/,-- Shire plc (LSE: SHP, NASDAQ: SHPGY, ... the waiting period under,Hart-Scott-Rodino Antitrust Improvements Act of ... (human TGF BETA 3) from Renovo Group plc,(LSE: ... with its terms, the,License Agreement became effective on ...
Cached Biology Technology:Expiry of Hart-Scott-Rodino Waiting Period for JUVISTA(R) (Human TGF BETA 3) 2Expiry of Hart-Scott-Rodino Waiting Period for JUVISTA(R) (Human TGF BETA 3) 3
... LCMSsolution software offers an ... simplified instrument control, diverse data ... compliance requirements. Comprehensive functions include ... and data management in both ...
This free-standing laminar flow hood provides a vertical flow of HEPA-filtered air to create a clean processing area. It includes a fluorescent light and motorized sliding shield. Options include wor...
... CromoCenSC is a chromogenic medium for ... of Salmonella (except S. thyphi) and ... ,The detection takes a maximum of ... tests, no sterilization during preparation and ...
Large-capacity refrigerated incubator chamber holds up to 4 independently-operated shakers. Programmable heat, refrigeration, humidifcation are standard. Photosynthetic operation, optional....
Biology Products: