Thomas S. Vierbuchen, PhD [HHMI Fellow] with his sponsor Michael E. Greenberg, PhD, at Harvard Medical School, Boston, Massachusetts, aims to understand how neurons adapt to experience by modifying the complement of genes they express. He is using high-throughput sequencing-based approaches to identify and characterize the function of genomic regulatory elements that control neuronal activity-regulated gene transcription.
Eric M. Woerly, PhD, with his sponsor Eric N. Jacobsen, PhD, at Harvard University, Cambridge, Massachusetts, aims to develop new chemical synthetic methods for the preparation of cancer therapeutics. The introduction of fluorine into pharmaceutical targets is an important element of drug design. The controlled, selective synthesis of fluorinated compounds, however, can be a great synthetic challenge. He plans to enable access to such targets by developing a method for the asymmetric synthesis of fluorinated small molecules, potentially leading to improved cancer therapies.
|Contact: Yung S. Lie, Ph.D.|
Damon Runyon Cancer Research Foundation