November 2012 Damon Runyon Fellows:
Nicholas Arpaia, PhD [Robert Black Fellow] with his sponsor Alexander Rudensky, PhD, at Memorial Sloan-Kettering Cancer Center, New York, New York, focuses on how the immune system distinguishes between beneficial gut bacteria versus those that may be pathogenic and cause disease. Changes in the levels of these microbes are correlated with cancer-associated intestinal inflammatory disorders like Crohn's disease and ulcerative colitis. His research may aid in the development of new therapeutics aimed at treating aberrant inflammation that can lead to cancer.
Christine R. Beck, PhD [HHMI Fellow] with her sponsor James R. Lupski, MD, PhD, at Baylor College of Medicine, Houston, Texas, is investigating the mechanisms that are involved in complex genomic rearrangements, such as gene duplications and triplications. Studying the mechanisms by which copy number changes occur may elucidate fundamental processes that lead to cancer in humans.
Alba Diz Muoz, PhD, with her sponsors Orion D. Weiner, PhD, at University of California, San Francisco, California, and Daniel A. Fletcher, PhD, at University of California, Berkeley, California, aims to develop a precise understanding of how cells migrate and decipher the differences between cell migration in a physiological context (such as immune cells) and that of a cancer cell. She will determine how physical forces affect specific molecular components of the signaling pathway that directs motility.
Lydia Finley, PhD, with her sponsor Craig B. Th
|Contact: Yung S. Lie, PhD|
Damon Runyon Cancer Research Foundation