Navigation Links
Damon Runyon Cancer Research Foundation awards $3.6 M to 9 top young clinical investigators
Date:7/1/2013

eatments for lung cancer to date are the targeted drugs erlotinib and crizotinib. These drugs block tumor growth in cancers that respectively harbor either mutations in EGFR or translocations in the ALK gene. Unfortunately, only a minor fraction of patients' tumors have EGFR mutations or ALK translocations; therefore, the vast majority of patients lack an effective targeted therapy.

Dr. Nijhawan aims to identify novel targets in lung cancer so that similarly effective therapy can be developed for other patients. He has identified a set of chemicals called benzothiazoles that are effective in blocking the growth of 25% of lung cancer cell types tested. The protein target of the benzothiazole and the genetic alterations that predict sensitivity are unknown. His research focuses on identifying both the benzothiazole protein target as well as predictive biomarkers that explain why only certain lung cancers are susceptible to its effect. The identification of these biomarkers in lung cancer patients may highlight a set of patients who could be treated with benzothiazole-related compounds.

Dr. Nijhawan works under the mentorship of Steve L. McKnight, PhD, and David Johnson, MD, at UT Southwestern Medical Center, Dallas, Texas.

Cameron J. Turtle, MD, PhD

Hematopoietic stem cell transplantation (HCT) is a potentially curative procedure for patients with hematologic malignancies who are otherwise incurable with conventional therapies. Despite advances in post-transplant care, the morbidity and mortality of complications such as graft versus host disease (GVHD) and infections remain significant limitations, and hinder the application of this life-saving procedure. Infection and GVHD are influenced by the immune system, which in turn is regulated by the bacterial contents of the human gastrointestinal tract.

Dr. Turtle will test the hypotheses that alterations in the bacterial composition of the human gastrointestinal tract
'/>"/>

Contact: Yung S. Lie
yung.lie@damonrunyon.org
212-455-0521
Damon Runyon Cancer Research Foundation
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related biology news :

1. Damon Runyon Cancer Research Foundation grants prestigious awards to 17 young scientists
2. Damon Runyon-Rachleff Innovation Awards granted for pioneering ideas in cancer research
3. ACRG and BGI report new evidence for the genetic bases of liver cancer
4. Cancer is a result of a default cellular safe mode, physicist proposes
5. Continued research needed on treatment for women with lung cancer who are never smokers
6. TGen and Ventana Medical Systems Inc. join forces to fight cancer
7. National Institutes of Health to fund research probing proteins linked to cancer, diabetes
8. Herding cancer cells to their death
9. No danger of cancer through gene therapy virus
10. An article in Cell reveals a new resistance mechanism to chemotherapy in breast and ovarian cancer
11. Osteoporosis drug stops growth of breast cancer cells, even in resistant tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/1/2015)...   Medisafe ™, the leading global medication management ... and Android smartphones and tablets, announces ... platform to allow patients to track and correlate their ... patients will be able to visualize in real-time how ... such as glucose levels and blood pressure. ...
(Date:3/24/2015)... and Markets ( http://www.researchandmarkets.com/research/hdgz7h/global_iris ) has announced ... 2015-2019" report to their offering. The ... at a CAGR of 23.5 percent over the period ... and the growth prospects of the Global Iris Recognition ... size, the report considers the revenue generated from sales ...
(Date:3/23/2015)... 23, 2015   HOYOS Labs , a leading ... announced that the Company will demonstrate multiple biometrics-based technologies ... consumers at Connect:ID on March 23 through 25, 2015, ... will highlight the IEEE Biometric Open Protocol Standard; free ... enterprise access control system. BOPS was invented by HOYOS ...
Breaking Biology News(10 mins):Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 2HOYOS Labs to Showcase Host of Biometrics Technologies at Connect:ID in Washington, D.C. 3
... Foldit called some strategies "shocking" in how well they ... scientists., Gamers made headlines in September for unraveling the ... Today, in a paper published online at the ... University of Washington researchers reveal the creative power of ...
... Anyone reading this article is doing it right now. But ... of Virginia Tech College of Engineering researchers has published a ... that details how to learn just that, using microelectromechanical systems ... body through the air we intake. The research paper, ...
... professionals and researchers across the globe believe they are on ... lead to paralysis and death. Despite successful eradication in most ... considered endemic -- and many more in which the virus ... University,s Sackler Faculty of Medicine and the Israeli Ministry of ...
Cached Biology News:Paper uncovers power of Foldit gamers' strategies 2Paper uncovers power of Foldit gamers' strategies 3Researchers using new technology to study breath for toxins 2Researchers using new technology to study breath for toxins 3Polio still a threat to public health 2Polio still a threat to public health 3
(Date:4/21/2015)... Invetech , a global leader ... contract manufacturing, and  NanoCellect Biomedical, a company ... sorting technology for life science researchers, today announced ... platform. Headquartered in San ... microchip-based cell sorting technology. NanoCellect,s flow cytometry platform ...
(Date:4/21/2015)... 2015  scPharmaceuticals, Inc., a privately held ... subcutaneous delivery, announced today that it has ... proprietary drug product, Furosemide Injection Solution, for ... heart failure. Concurrently with its ... patch pump.  The patch pump is designed ...
(Date:4/21/2015)... 2015 Leading-edge research into ... will be presented at the 2nd International ... and clinicians from academia, industry and government ... Invibio Biomaterial Solutions. The world-leading solutions provider ... manufacturing and R&D for medical-device manufacturers, holds ...
(Date:4/20/2015)... VANCOUVER, British Columbia and ...   DelMar Pharmaceuticals, Inc. (OTCQX: DMPI) ... on developing and commercializing proven cancer therapies in ... data at the 106th Annual Meeting of ... Annual Meeting on the potential for its lead ...
Breaking Biology Technology:NanoCellect And Invetech Announce Collaboration To Develop Novel Flow Cytometry Platform For Cell Sorting And Analysis 2NanoCellect And Invetech Announce Collaboration To Develop Novel Flow Cytometry Platform For Cell Sorting And Analysis 3scPharmaceuticals Announces Start of Pivotal Trial for Novel Furosemide Solution for Subcutaneous Delivery 2scPharmaceuticals Announces Start of Pivotal Trial for Novel Furosemide Solution for Subcutaneous Delivery 32nd International PEEK Meeting: Invibio Biomaterial Solutions spearheads medical research for implantable PEEK polymer devices 22nd International PEEK Meeting: Invibio Biomaterial Solutions spearheads medical research for implantable PEEK polymer devices 3DelMar Pharmaceuticals Presents Promising Preclinical Data on VAL-083's Potential to Treat Temozolomide-Resistant Glioblastoma Multiforme (GBM) 2DelMar Pharmaceuticals Presents Promising Preclinical Data on VAL-083's Potential to Treat Temozolomide-Resistant Glioblastoma Multiforme (GBM) 3DelMar Pharmaceuticals Presents Promising Preclinical Data on VAL-083's Potential to Treat Temozolomide-Resistant Glioblastoma Multiforme (GBM) 4DelMar Pharmaceuticals Presents Promising Preclinical Data on VAL-083's Potential to Treat Temozolomide-Resistant Glioblastoma Multiforme (GBM) 5
... Biophysical Society,s 55th Annual Meeting takes place from March ... MD. There, more than 6,500 scientists will gather to ... technology at every level of biophysics -- from atoms ... The Biophysical Society is the largest association in the ...
... graphene. A two-dimensional sheet of carbon one atom thick, ... through the material with 100 times the mobility they ... challenging, say researchers at the National Institute of Standards ... graphene on a substrate transforms its bustling speedway into ...
... Jan. 20, 2011 Ardea Biosciences, Inc. (Nasdaq: ... previously announced underwritten public offering of 2,750,000 shares of ... public of $26.00 per share. The gross proceeds to ... million, before deducting the underwriting discount and other estimated ...
Cached Biology Technology:Biophysical Society to Hold 55th Annual Meeting in Baltimore, Maryland, March 5-9, 2011 2Real-world graphene devices may have a bumpy ride 2Ardea Biosciences Prices Public Offering of Common Stock 2Ardea Biosciences Prices Public Offering of Common Stock 3