Navigation Links
Damon Runyon Cancer Research Foundation awards $3.6 M to 9 top young clinical investigators
Date:7/1/2013

NEPC tumors for recurrent molecular alterations and determine their functional and clinical impact. She will identify a genomic profile that distinguishes NEPC from the more common type of prostate cancer, prostate adenocarcinoma, and evaluate the impact of NEPC-associated alterations on patient outcomes and their ability to predict patient response to available therapies. Her goal is to improve our understanding of molecular events associated with disease progression and help develop strategies toward preventing NEPC. Distinguishing NEPC will help identify prostate cancer patients unlikely to benefit from additional AR-targeted strategies and select patients for novel targeted treatment approaches for NEPC.

Dr. Beltran works under the mentorship of Mark A. Rubin, MD, at Weill Medical College of Cornell University, New York, New York.

Christine M. Lovly, MD, PhD

Lung cancer is responsible for more cancer-related deaths in the U.S. and worldwide each year than any other cancer. Historically, patients with advanced metastatic disease have been treated with conventional chemotherapy. Recently, however, subsets of lung cancer patients have been identified with specific molecular alterations that allow for treatment with rationally chosen targeted therapies. One molecular subset of lung cancer is characterized by the presence of alterations in a protein called ALK tyrosine kinase. Patients with lung cancers that harbor ALK fusions derive significant clinical benefit from a newly approved drug that blocks the action of the mutant ALK. Unfortunately, the degree and duration of tumor response to ALK inhibitor drugs varies, and patients inevitably develop progressive disease, or "acquired resistance." Additional strategies are needed to improve the treatment of these lung cancer patients.

Dr. Lovly's goal is to develop novel treatment strategies for ALK positive lung cancer.

She plans to improve our understanding of how ALK fusions
'/>"/>

Contact: Yung S. Lie
yung.lie@damonrunyon.org
212-455-0521
Damon Runyon Cancer Research Foundation
Source:Eurekalert

Page: 1 2 3 4 5 6 7

Related biology news :

1. Damon Runyon Cancer Research Foundation grants prestigious awards to 17 young scientists
2. Damon Runyon-Rachleff Innovation Awards granted for pioneering ideas in cancer research
3. ACRG and BGI report new evidence for the genetic bases of liver cancer
4. Cancer is a result of a default cellular safe mode, physicist proposes
5. Continued research needed on treatment for women with lung cancer who are never smokers
6. TGen and Ventana Medical Systems Inc. join forces to fight cancer
7. National Institutes of Health to fund research probing proteins linked to cancer, diabetes
8. Herding cancer cells to their death
9. No danger of cancer through gene therapy virus
10. An article in Cell reveals a new resistance mechanism to chemotherapy in breast and ovarian cancer
11. Osteoporosis drug stops growth of breast cancer cells, even in resistant tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... research at the University of Adelaide has opened the way ... to powdery mildew. , In Australia, annual barley production is ... Powdery mildew is one of the most important diseases of ... have discovered the composition of special growths on the cell ... fungus into the leaf. , The research, by the ARC ...
(Date:7/25/2014)... for Medical Research have identified the functions of ... to triggering the mating process in mice. , They ... detect pheromones that indicate when a female is present. ... the female mouse is ovulating and ready to mate. ... Stowers, researchers believe mice developed this system through evolution ...
(Date:7/24/2014)... many sobering examples of how wildlife loss leads to ... co-authored by Wildlife Conservation Society (WCS) Health & ... Golden, calls for an interdisciplinary approach to tackle global ... supports about 15% of the world,s people and provides ... poor. It should come as no surprise that today,s ...
Breaking Biology News(10 mins):New hope for powdery mildew resistant barley 2It takes two to court 2It takes two to court 3New study draws links between wildlife loss and social conflicts 2
... A Web site is a better source of information ... to a study of low-income mothers reported in the January ... http://www.jneb.org/) . Led by Kami J. Silk, Ph.D., of ... mothers with nutrition information in different formats. One group ...
... stars have understudies. Now, an increasingly popular radioactive ... by researchers at the National Institute of Standards ... medical imaging, speed up clinical trials of many ... medical treatment. The number of medical images ...
... knees on your list of New Year,s resolutions? ... wait longer to pursue knee-replacement surgery than men do. ... stand the pain, these women may also risk putting ... according to Lynn Snyder-Mackler, Distinguished Alumni Professor in UD,s ...
Cached Biology News:For nutrition info, moms like the Web best 2Radioactive 'understudy' may aid medical imaging, drug development 2Listen-up ladies: Don't postpone knee-replacement surgery 2Listen-up ladies: Don't postpone knee-replacement surgery 3
(Date:7/24/2014)... 2014 -- A novel combination of microscopy and data ... Oak Ridge National Laboratory an unprecedented look at the ... and electrochemical properties. , The research team led ... surface of a perovskite manganite, a complex material that ... to understand surface behavior could benefit researchers who are ...
(Date:7/24/2014)... on sophisticated equipment, trained personnel, and detection dogs ... terrorist attacks. A revolutionary new electronic chip with ... job much easier. , The groundbreaking nanotechnology-inspired sensor, ... University ,s School of Chemistry and Center for ... company Tracense, picks up the scent of explosives ...
(Date:7/24/2014)... 2014 Research and Markets has ... Market 2014-2018" report to their offering.  ... is the in vitro growth of plant or animal ... and biopharmaceutical production. Cell culture is a crucial step ... and cell culture consumables are necessary for the in ...
(Date:7/24/2014)... Three companies from the angelMD network were ... Competition. Out of 700 competition entrants, Chiron Health, Litesprite, ... round. In this round twenty teams are invited to ... mentoring from thought-leaders and medical entrepreneurs from all over ... commitment to the Livestrong vision around the Big C ...
Breaking Biology Technology:ORNL study reveals new characteristics of complex oxide surfaces 2Nano-sized chip 'sniffs out' explosives far better than trained dogs 2Global Cell Culture Market 2014-2018: Key Vendors are Becton, Dickinson and Co, EMD, GE Healthcare, Lonza Group, Sigma Aldrich and Thermo Fisher Scientific 23 angelMD Startups Make Livestrong Big C Semi-finals 2
... backorders and new product pipeline provide positive outlook ... plans to lay off workers at its Chippewa Falls ... company has a recorded a significant increased order backlog ... $51 million and up from $75 million in the ...
... issue, I noted that while wireless communications were about to ... rather uninspired. For all the hype around mobile data services, ... - the fare that was easier and cheaper to receive ... , ,Then I had a pretty busy week, visiting with ...
... song Bits and Pieces is a good metaphor for the apparently ... early stage financing efforts to get life science companies off the ... some of these pieces so the tapestry doesnt fall apart. Last ... on my negligence in mentioning other seed and early stage life ...
Cached Biology Technology:Cray reports $54.5 million loss, plans layoff in Chippewa Falls 2Cray reports $54.5 million loss, plans layoff in Chippewa Falls 3Readers respond - Imagining the possibilities 2Readers respond - Imagining the possibilities 3More Midwest Seed-Stage Life Science VCs 2More Midwest Seed-Stage Life Science VCs 3More Midwest Seed-Stage Life Science VCs 4More Midwest Seed-Stage Life Science VCs 5More Midwest Seed-Stage Life Science VCs 6
The Cellject Elecroporator is suitable for all cell types including embryo, mammalian, plant, yeast and bacterial. Its has highly user-freindly programing and can be used remotely, for example in a l...
... E. coli containing a clone of the human ... Topoisomerase II alters the topological state of nucleic ... a transient break which generates a separate DNA ... double-stranded DNA passage mechanism, the enzyme can relax ...
Maxi XL Hybridization Oven for Extra Large bottles. 6 bottle (70 mm) rotisserie + shaker tray available for simultaneous use. Includes linear and orbital shaker trays, 4 extra large bottles, pack o...
... Cell Expansion Kit - Monolayer is a system ... as a monolayer in a serum-free environment. The ... Supplement, which has been optimized for neural stem ... (1996) Genes & Development 10 :3129). Human ...
Biology Products: