Navigation Links
Damaged hearts pump better when fueled with fats
Date:5/4/2011

Contrary to what we've been told, eliminating or severely limiting fats from the diet may not be beneficial to cardiac function in patients suffering from heart failure, a study at Case Western Reserve University School of Medicine reports.

Results from biological model studies conducted by assistant professor of physiology and biophysics Margaret Chandler, PhD, and other researchers, demonstrate that a high-fat diet improved overall mechanical function, in other words, the heart's ability to pump, and was accompanied by cardiac insulin resistance.

"Does that mean I can go out and eat my Big Mac after I have a heart attack," Dr. Chandler says "No, but treatments that act to provide sufficient energy to the heart and allow the heart to utilize or to maintain its normal metabolic profile may actually be advantageous."

The research, published in American Journal of Physiology-Heart and Circulatory Physiology, suggests that for a damaged heart, a balanced diet that includes mono- and polyunsaturated fats, and which replaces simple sugars (sucrose and fructose) with complex carbohydrates, may be beneficial.

In a healthy person, the heart uses both fats and carbohydrates to obtain the energy it needs to continue pumping blood 24/7. Ideally, fats are utilized because they yield more energy. However, if a person develops heart failure (or suffers from ischemia a lack of blood supply), the heart seems to prefer using glucose for fuel, because glucose requires less oxygen to produce energy.

While heart disease remains the leading cause of death in the United States, more people are surviving heart attacks that ever before. Survivors though pay a price for this improved survival, living with a damaged heart that usually progresses to heart failure. And unfortunately, medications and procedures have yet to "cure" heart failure, or halt the deterioration of heart function.

Upon initiation of these dietary interv
'/>"/>

Contact: Jessica Studeny
jessica.studeny@case.edu
216-368-4692
Case Western Reserve University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Mammals can be stimulated to regrow damaged inner retina nerve cells
2. Stem cells replace stroke-damaged tissue in rats
3. Activated stem cells in damaged lungs could be first step toward cancer
4. Mouse brain rewires its neural circuits to recuperate from damaged neural function after stroke
5. Exposure to alkaline substances can result in damaged teeth
6. Mobilizing the repair squad: Critical protein helps mend damaged DNA
7. Cells can read damaged DNA without missing a beat
8. U of I researchers say foliar fungicides may not be the answer for hail-damaged corn
9. UDs Zhuang wins NSF Early Career Award for research on how cells bypass damaged DNA
10. Endometrial stem cells could repair brain cells damaged by Parkinsons disease
11. SRNL works to decrease hazards from mold in water damaged homes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... SHENZHEN , Chine, 31 juillet 2015 /PRNewswire/ ... (ICG-10, www.icg-10.org ) sera organisée par le ... Shenzhen en Chine. ... année. Depuis son inauguration en 2006, l,ICG est ... influentes dans le domaine des « omiques » et c,est ...
(Date:7/31/2015)... SHENZHEN, China , 31. Juli 2015 Die ... ) wird von BGI veranstaltet und findet vom ... Shenzhen, China , statt. ... Jubiläum. Seit ihrem Start 2006 ist die ICG ... Bereich „omik" geworden. Sie ist eines der dynamischsten, ...
(Date:7/31/2015)... 31, 2015 The 10 th International Conference ... BGI from October 22-25, 2015, in Shenzhen , ... is celebrating its 10 th anniversary this year. Since its ... most influential annual meetings in the ,omics, fields, and is ... ICG-10 focuses on recent breakthroughs and advances ...
Breaking Biology News(10 mins):La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 2La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 3Die 10. internationale Konferenz zu Genomik (ICG-10) beginnt im Oktober 2Die 10. internationale Konferenz zu Genomik (ICG-10) beginnt im Oktober 3The 10th International Conference on Genomics (ICG-10) to Open in October 2
... Thinking about adopting a perky little puppy as a friend for ... cats and dogs? Think again. New research at Tel Aviv ... a new recipe for success. According to the study, if the ... when still young (less than 6 months for kittens, a year ...
... Department of Energy Joint Genome Institute (DOE JGI) ... Genomes (IMG) data management system, updated the content ... system, and has launched its educational companion site, ... microbial genomes from Version 29 release of the ...
... (ACCP) has awarded John van den ... Pharmacology at Children,s National Medical Center, its annual ... a neonatologist by training, receives this award for ... pharmacology," according to the ACCP. The Distinguished ...
Cached Biology News:The truth about cats and dogs 2DOE JGI extends the capabilities of the Integrated Microbial Genome System 2DOE JGI extends the capabilities of the Integrated Microbial Genome System 3
(Date:7/30/2015)... 2015  Discovery Laboratories, Inc. (Nasdaq: DSCO ... second $1.0M tranche under a previously awarded Phase ... at up to $3.0 million to support continued ... a potential medical countermeasure to mitigate acute and ... an initial $1.0 million under this grant in ...
(Date:7/30/2015)... (PRWEB) , ... July 30, 2015 , ... ... for advanced fluid applications and designed for continuous operation up to 1500 bar. ... sterilization-in-place, ensuring safety, efficiency, and preventing toxic contamination. , The Pony™ NS2006L homogenizer ...
(Date:7/29/2015)... 2015 Sanofi, un leader ... résultats pour le premier semestre 2015. Le Directeur ... Visionner l,interview vidéo et lire la ... Au sommaire de l,interview :  ... croissance - Diabète - ...
(Date:7/29/2015)... , July 29, 2015 US-Australian drug ... ) today confirmed it is committed to progressing its ... soon as practicable and to ensure the Company delivers ... Executive Officer, Iain Ross , said the Company ... the lead pre-clinical programs, discovery programs and academic partnerships ...
Breaking Biology Technology:Discovery Labs Receives $1.0 million under an SBIR Grant in Continuing Support of the Development of Aerosolized KL4 Surfactant to Address Radiation-Induced Lung Injury 2Discovery Labs Receives $1.0 million under an SBIR Grant in Continuing Support of the Development of Aerosolized KL4 Surfactant to Address Radiation-Induced Lung Injury 3GEA Announces the Pony™ NS2006L… a Self-contained, High Pressure Lab Homogenizer for Product Development Ensuring Maximum Efficiency and Safety 2Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 2Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 3Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 4Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 5Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 6Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 7Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 8Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 9Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 10
... Mass. Researchers at the Harvard School of ... and theoretically that the surface plasmon resonances of ... considerably narrower spectral widths than those of isolated ... significantly more intense in a periodic array, the ...
... can reveal critical evidence, as well as an identity, ... Purdue University that detects trace amounts of explosives, drugs ... The new technology also can distinguish between overlapping fingerprints ... current optical forensic methods. , A team led by ...
... Technology (NIST) have developed a radical new method of focusing ... one nanometer (one billionth of a meter).* Because of the ... range of ions tailored to the task at handit is ... smaller features on semiconductors than now are possible and for ...
Cached Biology Technology:Surface plasmon resonances of metal nanoparticles in array can have narrower spectral widths 2Fingerprints provide clues to more than just identity 2Cold atoms could replace hot gallium in focused ion beams 2
Mouse monoclonal antibody raised against a partial recombinant ALPK3. NCBI Entrez Gene ID = ALPK3...
Mouse monoclonal antibody raised against a partial recombinant MYO7A. NCBI Entrez Gene ID = MYO7A...
... Lines ,High Quality, Functionally-Validated, Ion Channel Cell ... for having a critical role in nerve ... key function in pain, CNS and the ... been investigated in therapeutic areas, such as ...
Mouse monoclonal antibody raised against a partial recombinant ENTPD5. NCBI Entrez Gene ID = ENTPD5...
Biology Products: