Navigation Links
Damage inflicted during cardiac attacks more widespread, MSU researchers find
Date:11/11/2008

EAST LANSING, Mich. Cholesterol crystals released in the bloodstream during a cardiac attack or stroke can damage artery linings much further away from the site of the attack, leaving survivors at greater risk than previously thought.

George Abela, a physician in Michigan State University's College of Human Medicine and chief of the Department of Medicine's cardiology section, is leading innovative research into the role that the crystallization and expansion of cholesterol play in heart attacks, strokes and other cardiovascular events in humans.

He presented his latest research this week at the American Heart Association's Scientific Sessions meeting in New Orleans.

In recent medical trials, Abela and his team of researchers tested carotid arteries in a laboratory by injecting cholesterol crystals into them.

"Cholesterol has been shown to expand when crystallizing and then be released into the circulation following a cardiac event," Abela said. "We found that the flow of sharp-ended crystals in arteries damage the lining of arteries and decrease the ability of arteries to dilate properly at intervals far away from the site of the attack."

Abela compared the process to a tree, with the trunk as the site of the cardiac event and the branches representing arteries where damage is afflicted far away from the trunk.

"These findings have important clinical implications," Abela said. "We found the original injury was being transmitted downstream. We may need to expand the testing that we have patients undergo to make sure more damage is not being done during a cardiac attack or stroke."

The American Heart Association's Scientific Sessions annual meeting is the premier cardiovascular research and instructional meeting in the world, drawing nearly 20,000 doctors, researchers and cardiac professionals.


'/>"/>

Contact: Jason Cody
codyja@msu.edu
517-432-0924
Michigan State University
Source:Eurekalert

Page: 1

Related biology news :

1. Human derived stem cells can repair rat hearts damaged by heart attack
2. Enzyme alerts cells powerful army to repair DNA damage
3. Simulation reveals how body repairs balance after damage
4. Mixing large doses of both acetaminophen painkiller and caffeine may increase risk of liver damage
5. MIT: Human-generated ozone will damage crops
6. Coral reefs will be permanently damaged without urgent action
7. Even minute levels of lead cause brain damage in children
8. Cigarette smoke, alcohol damage hearts worse as combo
9. Club drugs inflict damage similar to traumatic brain injury
10. An ambulance man for muscle damage
11. Why diving marine mammals resist brain damage from low oxygen
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... , March 23, 2017 The report "Gesture Recognition and ... Industry, and Geography - Global Forecast to 2022", published by MarketsandMarkets, the market ... CAGR of 29.63% between 2017 and 2022. Continue ... ... ...
(Date:3/22/2017)... , March 21, 2017   Neurotechnology , ... recognition technologies, today announced the release of the ... which provides improved facial recognition using up to ... a single computer. The new version uses deep ... accuracy, and it utilizes a Graphing Processing Unit ...
(Date:3/22/2017)... LIVERMORE, Calif. , March 21, 2017 ... recognition analytics company serving law enforcement agencies, announced today ... Sheridan as director of public safety business development. ... of diversified law enforcement experience, including a focus on ... Vigilant. In his most recent position, Mr. Sheridan served ...
Breaking Biology News(10 mins):
(Date:8/23/2017)... ... August 23, 2017 , ... ... ability to manipulate 3D models of pediatric patients’ neuroanatomy and accurately tailor radiation ... of the Journal of Medical Imaging. The advance is reported in an article ...
(Date:8/23/2017)... ... 22, 2017 , ... Patients suffering from gum disease and failing implants now ... Malik. Dr. Malik, of Broward Center for Laser Periodontics and Implants , ... future of dentistry with regenerative periodontal procedures. , "I initially became ...
(Date:8/23/2017)... Virginia (PRWEB) , ... August 23, 2017 , ... NDA ... PhD, former Director of the Office of Device Evaluation at the FDA’s Center for ... industries, has joined the firm as an Expert Consultant. , Prior to his FDA ...
(Date:8/22/2017)... ... August 22, 2017 , ... One ... is the practice of opioid-dose sparing. Opioid-dose sparing refers to the reduction of ... including with non-steroidal anti-inflammatory drugs (NSAIDs). , The potential for new therapies to ...
Breaking Biology Technology: