Navigation Links
DNA stretching -- A new technique being carried out at CIC microGUNE to detect illnesses
Date:4/5/2011

This release is available in Spanish.

Making DNA sequences being passed through nanochannels a thousand times thinner than a human hair to the point that they take on the form of diminutive spaghetti. This is an innovative technique, known as DNA stretching, and is one of the lines of research in which CIC microGUNE is working, and about which they have already published two scientific articles and are shortly to apply for a patent. The technique basically consists of the analysis of a single molecule of DNA, after stretching it, measuring its length and analysing its sequence.

This novel technology could become a simpler and more effective alternative than current methods to analysing DNA and, in this manner, apply it in order to know the predisposition for suffering certain illnesses, diagnosing them or establishing the best therapy once its development is known. The method will also enable other applications, such as the identification of bacteria and viruses, carrying out forensic diagnoses or providing systems for the advancement of therapies for chronic diseases.

In order to stretch DNA molecules, it is necessary to make them pass through channels of tiny dimensions. The Micro- and Nano-engineering Unit at CIC microGUNE, basing itself on known technology such as nanoprinting lithography, has manufactured devices that contain sealed channels of 50 nanometres.

The elements manufactured by CIC microGUNE form part of specific lab-on-a-chip series of devices known as single molecule devices, which enable carrying out a multitude of tasks using a tiny quantity of DNA practically the content of a single cell.

"This technology enables determining DNA sequences, detecting genetic alterations that determine specific genes associated with the early detection of illnesses", explained Mr Santos Merino, researcher at CIC microGUNE. This same detection can predict the susceptibility of certain populations of individuals to certain medication (what is known as Pharmacogenetics). The design of these kinds of chips will provide fast, cheap and in-situ (health centre walk-in or out-patient) detection.

Rapid diagnosis CIC microGUNE's commitment

The project demonstrates what the main commitment by CIC microGUNE when targeting their research work over the nest few years: health sciences. This is the area where the Basque centre believes the greatest opportunities will arise for developing new products to improve current technology and, in the end, contribute to the enhancement of the wellbeing of persons.

And, within this sphere, one of the niches where a considerable part of their projects are concentrated is in rapid diagnoses: developing devices which enable detecting pathologies on the spot and in any patient care environment. These devices, able to carry out diagnoses through biomolecular analysis, will be very small, cheap and disposable, which, together with their ease of use, will enable them to be used in any situation of patient care.


'/>"/>

Contact: Oihane Lakar
o.lakar@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
Source:Eurekalert

Related biology news :

1. Stretching molecules yields new understanding of electricity
2. Stretching the truth: JILA biophysicists help unravel DNA stretching mystery
3. NJIT professor finds engineering technique to identify disease-causing genes
4. New technique enables assessment of drought performance
5. New technique eliminates toxic drugs in islet transplant in diabetic mice
6. These shells dont clam up: Innovative technique to record human impact on coastal waters
7. Einstein researchers develop technique to count messages made by single genes
8. These shells dont clam up: Innovative technique to record human impact on coastal waters
9. Novel technique for fluorescence tomography of tumors in living animals
10. New edition of laboratory manual includes cutting-edge techniques to study gene regulation
11. New technique is quantum leap forward in understanding proteins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2016)... -- VoiceIt is excited to announce its new marketing ... working together, VoiceIt and VoicePass will offer an ... slightly different approaches to voice biometrics, collaboration between ... Both companies ... "This marketing and technology partnership allows VoiceIt ...
(Date:5/12/2016)... DALLAS , May 12, 2016 ... has just published the overview results from the Q1 ... of the recent wave was consumers, receptivity to a ... wearables data with a health insurance company. ... choose to share," says Michael LaColla , CEO ...
(Date:5/3/2016)... , May 3, 2016  Neurotechnology, a provider ... MegaMatcher Automated Biometric Identification System (ABIS) , ... multi-biometric projects. MegaMatcher ABIS can process multiple complex ... any combination of fingerprint, face or iris biometrics. ... SDK and MegaMatcher Accelerator , which ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... WA (PRWEB) , ... June 23, 2016 , ... ... announces the release of its second eBook, “Clinical Trials Patient Recruitment and Retention ... recruitment and retention in this eBook by providing practical tips, tools, and strategies ...
(Date:6/23/2016)... 23, 2016   Boston Biomedical , an ... designed to target cancer stemness pathways, announced that ... Orphan Drug Designation from the U.S. Food and ... cancer, including gastroesophageal junction (GEJ) cancer. Napabucasin is ... inhibit cancer stemness pathways by targeting STAT3, and ...
(Date:6/23/2016)... 23, 2016 A person commits a crime, and ... to track the criminal down. An outbreak of ... Drug Administration (FDA) uses DNA evidence to track down the ... Sound far-fetched? It,s not. The FDA has increasingly used a ... of foodborne illnesses. Put as simply as possible, whole genome ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... and Mold) microbial test has received AOAC Research Institute approval 061601. , “This ... introduced last year,” stated Bob Salter, Vice President of Regulatory and Industrial Affairs. ...
Breaking Biology Technology: