Navigation Links
DNA stretching -- A new technique being carried out at CIC microGUNE to detect illnesses
Date:4/5/2011

This release is available in Spanish.

Making DNA sequences being passed through nanochannels a thousand times thinner than a human hair to the point that they take on the form of diminutive spaghetti. This is an innovative technique, known as DNA stretching, and is one of the lines of research in which CIC microGUNE is working, and about which they have already published two scientific articles and are shortly to apply for a patent. The technique basically consists of the analysis of a single molecule of DNA, after stretching it, measuring its length and analysing its sequence.

This novel technology could become a simpler and more effective alternative than current methods to analysing DNA and, in this manner, apply it in order to know the predisposition for suffering certain illnesses, diagnosing them or establishing the best therapy once its development is known. The method will also enable other applications, such as the identification of bacteria and viruses, carrying out forensic diagnoses or providing systems for the advancement of therapies for chronic diseases.

In order to stretch DNA molecules, it is necessary to make them pass through channels of tiny dimensions. The Micro- and Nano-engineering Unit at CIC microGUNE, basing itself on known technology such as nanoprinting lithography, has manufactured devices that contain sealed channels of 50 nanometres.

The elements manufactured by CIC microGUNE form part of specific lab-on-a-chip series of devices known as single molecule devices, which enable carrying out a multitude of tasks using a tiny quantity of DNA practically the content of a single cell.

"This technology enables determining DNA sequences, detecting genetic alterations that determine specific genes associated with the early detection of illnesses", explained Mr Santos Merino, researcher at CIC microGUNE. This same detection can predict the susceptibility of certain populations of individuals to certain medication (what is known as Pharmacogenetics). The design of these kinds of chips will provide fast, cheap and in-situ (health centre walk-in or out-patient) detection.

Rapid diagnosis CIC microGUNE's commitment

The project demonstrates what the main commitment by CIC microGUNE when targeting their research work over the nest few years: health sciences. This is the area where the Basque centre believes the greatest opportunities will arise for developing new products to improve current technology and, in the end, contribute to the enhancement of the wellbeing of persons.

And, within this sphere, one of the niches where a considerable part of their projects are concentrated is in rapid diagnoses: developing devices which enable detecting pathologies on the spot and in any patient care environment. These devices, able to carry out diagnoses through biomolecular analysis, will be very small, cheap and disposable, which, together with their ease of use, will enable them to be used in any situation of patient care.


'/>"/>

Contact: Oihane Lakar
o.lakar@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
Source:Eurekalert

Related biology news :

1. Stretching molecules yields new understanding of electricity
2. Stretching the truth: JILA biophysicists help unravel DNA stretching mystery
3. NJIT professor finds engineering technique to identify disease-causing genes
4. New technique enables assessment of drought performance
5. New technique eliminates toxic drugs in islet transplant in diabetic mice
6. These shells dont clam up: Innovative technique to record human impact on coastal waters
7. Einstein researchers develop technique to count messages made by single genes
8. These shells dont clam up: Innovative technique to record human impact on coastal waters
9. Novel technique for fluorescence tomography of tumors in living animals
10. New edition of laboratory manual includes cutting-edge techniques to study gene regulation
11. New technique is quantum leap forward in understanding proteins
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/29/2016)... 2016 LegacyXChange, Inc. (OTC: ... SelectaDNA/CSI Protect are pleased to announce our successful effort ... variety of writing instruments, ensuring athletes signatures against counterfeiting ... from athletes on LegacyXChange will be assured of ongoing ... Bill Bollander , CEO states, "By ...
(Date:3/22/2016)... 2016 According to ... for Consumer Industry by Type (Image, Motion, Pressure, ... & IT, Entertainment, Home Appliances, & Wearable ... 2022", published by MarketsandMarkets, the market for ... USD 26.76 Billion by 2022, at a ...
(Date:3/21/2016)... , March 22, 2016 ... with passcodes for superior security   ... leading provider of secure digital communications services, today announced ... technology and offer enterprise customers, particularly those in the ... recognition and voice authentication within a mobile app, alongside, ...
Breaking Biology News(10 mins):
(Date:4/27/2016)... ... ... Shimadzu Scientific Instruments (SSI) will be showcasing a broad ... Expo. Shimadzu’s high-performance instruments enable laboratories to test cannabis products for potency, moisture, ... booth 1021 to learn how Shimadzu’s instruments can help improve QA/QC testing, peak ...
(Date:4/27/2016)... 2016 NanoStruck Technologies Inc. ... ( Frankfurt : 8NSK) gibt bekannt, ... 13. August 2015 die Genehmigung von der CNSX ... 200.000.000 Einheiten auf 400.000.000 Einheiten zu erhöhen, um ... wurden 157.900.000 Einheiten mit dem ersten Teil der ...
(Date:4/27/2016)... ... April 27, 2016 , ... NDA Partners Chairman ... as an Expert Consultant. Mr. Clark was formerly a Vice President with ... of small molecule monographs based on analytical methods. NDA Partners Expert Consultants ...
(Date:4/27/2016)... ... ... Global Stem Cells Group CEO Benito Novas announced that Duncan Ross, Ph.D. ... Labs in Miami. , In 2004, Ross received his Ph.D. in Immunology from the ... the suppression of graft vs. host disease (GVHD) under UM Professor Robert Levy Ph.D. ...
Breaking Biology Technology: