Navigation Links
DNA sequences need quality time too - guidelines for quality control published
Date:9/5/2012

Like all sources of information, DNA sequences come in various degrees of quality and reliability. To identify, proof, and discard compromised molecular data has thus become a critical component of the scientific endeavor - one that everyone generating sequence data is assumed to carry out before using the sequences for research purposes.

"Many researchers find sequence quality control difficult, though", says Dr. Henrik Nilsson of the University of Gothenburg and the lead author of a new article on sequence reliability, published in the Open Access journal MycoKeys. "There just isn't any straightforward document to put in their hands to give them a flying start. As a result, scientists differ in the degree to which they are aware of the need to exercise sequence quality control and in what measures they take." Previous studies have highlighted several shortcomings of publicly available DNA sequences - more than ten percent of the fungal DNA sequences may be misidentified at the species level, for example.

"A second complication", adds co-author Prof. Urmas Koljalg of the University of Tartu, "is that the software available for sequence quality management tend to be very complex and resource intensive. It borders on the unfair to expect everyone to have access to, and to master, such computer environments. Fortunately, a whole lot can be done towards quality control of DNA sequences using just manual means and a web browser. The
'/>"/>

Contact: Dr. Henrik Nilsson
henrik.nilsson@bioenv.gu.se
46-317-862-623
Pensoft Publishers
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Long-term research reveals causes and consequences of environmental change
2. New approach to spell checking gene sequences
3. Revolutionary project will obtain entire genome sequences in fight against Alzheimers
4. Research reveals contrasting consequences of a warmer Earth
5. Lower dosage CT-guided lung biopsy protocol maintains quality, minimizes exposure
6. Interventional radiology: Mitigating symptoms, improving quality of life of MS patients
7. Stoneflies mapped across Ohio, with implications for water quality and nature conservation
8. University of Toronto biologists predict extinction for organisms with poor quality genes
9. Culturally sensitive research in United Arab Emirates pinpoints indoor air quality risks
10. New tools for evaluating quality of life for cats, dogs with heart disease
11. Discovery may lead to new tomato varieties with vintage flavor and quality
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
DNA sequences need quality time too - guidelines for quality control published
(Date:9/23/2014)... The successful rise and fall of an athlete,s moving body ... tendons, putting the many angles and intersecting planes literally ... joint to the test. But it,s more than just a ... devastating of sports injuries: the ACL or anterior cruciate ligament ... sits at the center of the knee joint and ...
(Date:9/23/2014)... A multidisciplinary team at the University of Wisconsin-Madison and ... more affordable way to screen for neural toxins, helping ... National Institutes of Health (NIH) announced today that the ... support to continue the promising work as part of ... will receive approximately $7 million over the three-year project. ...
(Date:9/23/2014)... award funds to support the next phase of its ... of predicting drug safety and effectiveness. Researchers will collaborate ... chips and combine them into an integrated system that ... Led by the National Center for Advancing Translational Sciences ... million in 2014 with additional support over the remaining ...
Breaking Biology News(10 mins):Does size matter? MRI imaging sheds light on athletes most at risk for severe knee injury 2Does size matter? MRI imaging sheds light on athletes most at risk for severe knee injury 3UW-Madison team developing 'tissue chip' to screen neurological toxins 2UW-Madison team developing 'tissue chip' to screen neurological toxins 3NIH funds next phase of Tissue Chip for Drug Screening program 2NIH funds next phase of Tissue Chip for Drug Screening program 3NIH funds next phase of Tissue Chip for Drug Screening program 4
... just a single island in the remote South Pacific, is ... also one of the oldest flowering plants, having branched off ... Indiana University, with the U.S. Department of Energy Joint Genome ... Research for Development in New Caledonia, have determined a remarkable ...
... Ven, Department of Molecular Biology and Genetics and the ... microRNA-128 just published in Science . In the ... amount of microRNA-128 in specific neurons that react to ... in these neurons in neonatal mice, it results in ...
... a cloudless day in Dangriga, a coastal city in southern ... wall of their sun-strewn lab is lined with the usual ... tubes. Swathed in purple gloves, they measure samples, mix gels ... usual class this is not. It is part of ...
Cached Biology News:A gluttonous plant reveals how its cellular power plant devours foreign DNA 2A gluttonous plant reveals how its cellular power plant devours foreign DNA 3New research provides insight into epilepsy 2Beyond Mendel 2Beyond Mendel 3Beyond Mendel 4
(Date:9/23/2014)... September 23, 2014 Erlab , ... personnel since 1968 and Burdinola, supplier of laboratory furniture ... new filtered fume hood. , By integrating ... hood, Burdinola will now offer an innovative solution utilizing ... range of chemicals, best-in-class detection technology, and communication for ...
(Date:9/23/2014)... , Sept. 23, 2014 ... the "Proteomics Markets for Research and IVD ... Technologies)" report to their offering. ... for proteomics applications, both in their research use ... proteins, including the study of the structure and ...
(Date:9/23/2014)... (PRWEB) September 23, 2014 For the fifth ... Inc. 500|5000 list of the fastest-growing companies. , “We’re ... acknowledged yet again by Inc. Magazine,” ExakTime CEO Tony Pappas ... list by posting a three-year growth rate of 61 percent ... that time by more than 40 percent. , Pappas cited ...
(Date:9/23/2014)... 23, 2014 Follow us ... steady popularity the world over, due to its ... in the marketplace is expected to come from ... developing countries. Several sub-Saharan countries in the African ... already implemented genetically engineered crop production strategies. Rising ...
Breaking Biology Technology:Erlab Partners with Burdinola to Deliver an Innovative Filtered Fume Hood 2Proteomics Markets for Research and IVD Applications (Mass Spectrometry, Chromatography, Microarrays, Electrophoresis, Immunoassays, Other Technologies) 2Proteomics Markets for Research and IVD Applications (Mass Spectrometry, Chromatography, Microarrays, Electrophoresis, Immunoassays, Other Technologies) 3Proteomics Markets for Research and IVD Applications (Mass Spectrometry, Chromatography, Microarrays, Electrophoresis, Immunoassays, Other Technologies) 4ExakTime Makes Inc. 5000 List for the Fifth Time 2Rising Focus on Food Security Spurs Growth in the Global Agricultural Biotechnology Market, According to New Report by Global Industry Analysts, Inc. 2Rising Focus on Food Security Spurs Growth in the Global Agricultural Biotechnology Market, According to New Report by Global Industry Analysts, Inc. 3Rising Focus on Food Security Spurs Growth in the Global Agricultural Biotechnology Market, According to New Report by Global Industry Analysts, Inc. 4
... , SILVER SPRING, Md. , Feb. ... announced today that it will release its fourth quarter and ... February 16, 2010 . , United Therapeutics will host a ... 9:00 a.m. Eastern Time .  The teleconference is accessible ...
... Ind. , Feb. 9 The American Psychiatric Association ... to prepare and manage all industry-supported symposia (ISS) programming at its ... 22-26, 2010 . , CME Enterprise will manage all elements ... partnership with the APA. , "It is a tremendous honor ...
... , , , , , , LEUVEN, ... - Paper Examines the Potential of Microplasmin to Improve the Treatment,of ... ThromboGenics NV (Euronext Brussels: THR), a biopharmaceutical company,focused on the discovery ... today that the positive,microplasmin Phase II trial results, evaluating the product,s efficacy ...
Cached Biology Technology:CME Enterprise Named to Manage All Industry-Supported Symposia at 2010 APA Annual Meeting 2ThromboGenics - Positive Microplasmin Phase II Data Published in Ophthalmology 2ThromboGenics - Positive Microplasmin Phase II Data Published in Ophthalmology 3ThromboGenics - Positive Microplasmin Phase II Data Published in Ophthalmology 4
The PROTEAN II slab gel casting stand is a component of the PROTEAN II XL and xi casting apparatus. It is supplied with gaskets....
... The Dyad Disciple thermal cycler is a ... may also be operated independently, using a ... of interchangeable Alpha units (sample-holder, heat-pump assemblies), ... as the Chromo4 real-time detector. Peltier heat ...
...
I-Ab MHC Class II...
Biology Products: