Navigation Links
DNA sequences need quality time too - guidelines for quality control published
Date:9/5/2012

Like all sources of information, DNA sequences come in various degrees of quality and reliability. To identify, proof, and discard compromised molecular data has thus become a critical component of the scientific endeavor - one that everyone generating sequence data is assumed to carry out before using the sequences for research purposes.

"Many researchers find sequence quality control difficult, though", says Dr. Henrik Nilsson of the University of Gothenburg and the lead author of a new article on sequence reliability, published in the Open Access journal MycoKeys. "There just isn't any straightforward document to put in their hands to give them a flying start. As a result, scientists differ in the degree to which they are aware of the need to exercise sequence quality control and in what measures they take." Previous studies have highlighted several shortcomings of publicly available DNA sequences - more than ten percent of the fungal DNA sequences may be misidentified at the species level, for example.

"A second complication", adds co-author Prof. Urmas Koljalg of the University of Tartu, "is that the software available for sequence quality management tend to be very complex and resource intensive. It borders on the unfair to expect everyone to have access to, and to master, such computer environments. Fortunately, a whole lot can be done towards quality control of DNA sequences using just manual means and a web browser. The
'/>"/>

Contact: Dr. Henrik Nilsson
henrik.nilsson@bioenv.gu.se
46-317-862-623
Pensoft Publishers
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Long-term research reveals causes and consequences of environmental change
2. New approach to spell checking gene sequences
3. Revolutionary project will obtain entire genome sequences in fight against Alzheimers
4. Research reveals contrasting consequences of a warmer Earth
5. Lower dosage CT-guided lung biopsy protocol maintains quality, minimizes exposure
6. Interventional radiology: Mitigating symptoms, improving quality of life of MS patients
7. Stoneflies mapped across Ohio, with implications for water quality and nature conservation
8. University of Toronto biologists predict extinction for organisms with poor quality genes
9. Culturally sensitive research in United Arab Emirates pinpoints indoor air quality risks
10. New tools for evaluating quality of life for cats, dogs with heart disease
11. Discovery may lead to new tomato varieties with vintage flavor and quality
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
DNA sequences need quality time too - guidelines for quality control published
(Date:11/21/2014)... DALLAS , November 18, 2014 ... Security Systems Market by Systems (Video, RFID, Access Control, ... (SEZ, Factories, Hotels, Banks, Government), Component Service Geography - ... Security Systems Market is projected to be around $25 ... Billion by 2020, growing at a CAGR of 8.69%. ...
(Date:11/21/2014)... , Nov. 20, 2014 C-Labs LLC, ... the Internet of Things (IoT), today announced the appointment ... chief operating officer. Previously a strategic advisor to the ... and operations. Mr. Traynor is based out of the ... He reports to Chris Muench , Chief Executive ...
(Date:11/18/2014)... BOSTON , Nov. 17, 2014   ... HealthCare and EMC collaborate to develop The Partners ... , The Partners Data Lake will allow ... to improve diagnostics, treatment and the lives of ... support research and clinical activities across the Partners ...
Breaking Biology News(10 mins):Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 2Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 3Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 4Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 5
... , , , , , , ... , , AUDIO: ... increased amounts... , Click here for more information. ... , , , , , ...
... team of researchers from UCSF and UC San Diego has ... in lab and animal studies, suggesting it could offer a ... human dysentery throughout the world. Based on these ... drug, known as auranofin, from the U.S. Food and Drug ...
... /PRNewswire-iReach/ -- With chronic diseases continuing to ... research to find "cures" continuing to take in billions ... away," a small but growing sector is finding answers ... of healing practices that rely such unlikely factors as ...
Cached Biology News:Supercharged safflower 2Supercharged safflower 3Supercharged safflower 4Lab tests show arthritis drug effective against global parasite 2Lab tests show arthritis drug effective against global parasite 3Lab tests show arthritis drug effective against global parasite 4Healing Method from Australia Addresses the Human Genome 2
(Date:12/19/2014)... In contrast to traditional LED lights where ... Valoya uses proprietary LED technology to incorporate their spectra ... which is critical in low proximity installations. The Valoya ... its lifetime which is up to four times longer ... investment cost was clearly higher when compared to traditional ...
(Date:12/19/2014)... MILLBROOK, N.Y. , Dec. 18, 2014 Egenix, ... has been elected Chairman of the Board, to succeed ... President and CEO, but will continue as a member of ... that he has added to the company over almost twenty ... The Board of Directors has established a Search ...
(Date:12/17/2014)... Based on the revenues gained from surgical ... dominated by four major players contributing to approximately ... include GE Healthcare (U.K.), Siemens AG (Germany), Philips ... Report Copy at http://www.marketsandmarkets.com/Market-Reports/surgical-imaging-market-210534462.html , The ... to its strong product portfolio, which includes its ...
(Date:12/17/2014)... Once more, EMAAR has selected ... waste water treatment plant to phase one of BayLaSun, ... Two years ago Bioshaft successfully supplied and operated a ... residential towers with an occupancy of 900 residences. ... gallons per day and was signed on September 16th, ...
Breaking Biology Technology:Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 2Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 3Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 4
... 2012     On May 21-23, 2012, Diversity ... to support, mentor, and develop minority-, woman-, veteran/service-disabled-, ... its fifth annual networking conference and EXPO event.  ... advocate, will address the conference held at the ...
... RayBiotech, Inc. today announced that it has formally ... at academic and government research institutes in the United ... program, core diagnostics facilities will be able to provide ... their current services offerings at no cost to the ...
... 19, 2012  Phigenics LLC, an innovative water management services ... that demonstrates up to 33% false-positive test results for ... A false-positive result means the test indicated Legionella ... levels when in fact it was below detectable levels ...
Cached Biology Technology:Music Legend And Health Advocate Bret Michaels To Address Diversity Alliance For Science 2012 National Conference And EXPO 2Music Legend And Health Advocate Bret Michaels To Address Diversity Alliance For Science 2012 National Conference And EXPO 3RayBiotech, Inc. Announces New Diagnostic Core Facility Partnering Program 2Phigenics Research Challenges Accuracy Of Conventional Legionella Testing Protocol 2Phigenics Research Challenges Accuracy Of Conventional Legionella Testing Protocol 3
... of Total Canine Endostatin. Canine ... Science products include a line of ... and reagents used for multiple research ... kits are ultra-sensitive, quick and dependable ...
... Kit is a very sensitive immunohistochemical tool ... containing both anti-von Willebrand Factor and anti-CD31 ... variety of species. This AP kit provides ... of frozen and paraffin-embedded sections in human ...
... Many modifications of Eagle's ... the original formulation. The most ... Modified Eagle's,Medium. DME is a ... Eagle [MEM] that contains a ...
... OligoMix or individual RNA sequences from high throughput ... small RNAs from LC Sciences. These products provide ... millions) of DESIGNED sequences delivered in a microtube ... containing a single verified RNA sequence. This is ...
Biology Products: