Navigation Links
DNA sequences need quality time too - guidelines for quality control published
Date:9/5/2012

Like all sources of information, DNA sequences come in various degrees of quality and reliability. To identify, proof, and discard compromised molecular data has thus become a critical component of the scientific endeavor - one that everyone generating sequence data is assumed to carry out before using the sequences for research purposes.

"Many researchers find sequence quality control difficult, though", says Dr. Henrik Nilsson of the University of Gothenburg and the lead author of a new article on sequence reliability, published in the Open Access journal MycoKeys. "There just isn't any straightforward document to put in their hands to give them a flying start. As a result, scientists differ in the degree to which they are aware of the need to exercise sequence quality control and in what measures they take." Previous studies have highlighted several shortcomings of publicly available DNA sequences - more than ten percent of the fungal DNA sequences may be misidentified at the species level, for example.

"A second complication", adds co-author Prof. Urmas Koljalg of the University of Tartu, "is that the software available for sequence quality management tend to be very complex and resource intensive. It borders on the unfair to expect everyone to have access to, and to master, such computer environments. Fortunately, a whole lot can be done towards quality control of DNA sequences using just manual means and a web browser. The
'/>"/>

Contact: Dr. Henrik Nilsson
henrik.nilsson@bioenv.gu.se
46-317-862-623
Pensoft Publishers
Source:Eurekalert  

0

GOOD

Page: 1 2

Related biology news :

1. Long-term research reveals causes and consequences of environmental change
2. New approach to spell checking gene sequences
3. Revolutionary project will obtain entire genome sequences in fight against Alzheimers
4. Research reveals contrasting consequences of a warmer Earth
5. Lower dosage CT-guided lung biopsy protocol maintains quality, minimizes exposure
6. Interventional radiology: Mitigating symptoms, improving quality of life of MS patients
7. Stoneflies mapped across Ohio, with implications for water quality and nature conservation
8. University of Toronto biologists predict extinction for organisms with poor quality genes
9. Culturally sensitive research in United Arab Emirates pinpoints indoor air quality risks
10. New tools for evaluating quality of life for cats, dogs with heart disease
11. Discovery may lead to new tomato varieties with vintage flavor and quality
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
DNA sequences need quality time too - guidelines for quality control published
(Date:6/17/2013)... virus in patients with severe brain infections in Vietnam. ... is responsible for the symptoms of disease. , The ... of 644 patients with severe brain infections in the ... of the 122 patients with non-infectious brain disorders that ... nervous system are often fatal and patients who do ...
(Date:6/17/2013)... ST. LOUIS -- In research published in Biochemical ... describe a technology that can detect new, previously unknown ... for viruses even when doctors have not identified a ... , In the new approach, scientists use ... discover viruses. , Taking advantage of the complete deciphering ...
(Date:6/17/2013)... a sugar alcohol produced by fungi, bacteria, and algae, ... The sweetener is also used in the medical field ... to flush out excess fluids and used during surgery ... ease the passage of other drugs. , Now Profs. ... Department of Molecular Microbiology and Biotechnology and the Sagol ...
Breaking Biology News(10 mins):New virus isolated from patients with severe brain infections 2New virus isolated from patients with severe brain infections 3Saint Louis University researchers discover a way to detect new viruses 2Saint Louis University researchers discover a way to detect new viruses 3Artificial sweetener a potential treatment for Parkinson's disease 2
... , Dr. Don Walsh, who co-piloted the historic 1960 deep-sea voyage ... Navy in a ceremony on at 10 a.m. April 15 at ... the only living human to have visited the Challenger Deep ... Walsh is best-known for navigating the bathyscaphe (deep submergence vehicle) Trieste ...
... at The Scripps Research Institute have synthesized a new nano-scale scientific ... off as it detects metallic ions in its immediate surroundings. ... of the International Edition of the journal Angewandte Chemie, this molecule ... in the test tube, and it has potential to be developed ...
... with medical formulations to be accepted by the U.S. Food ... that has serious ethical and moral implications. New research in ... Tel Aviv University,s Faculty of Engineering holds a promise that ... experimental trials. Dr. Gefen,s research into fat cells, published ...
Cached Biology News:New nano-tool synthesized at Scripps Research Institute 2A lab rat -- created in the lab 2
(Date:6/18/2013)... PA (PRWEB) June 18, 2013 Demanding ... Ball Lenses engineered of synthetic Sapphire and Glass Ball ... sizes from Swiss Jewel Company , of Philadelphia ... by expanding and collimating the light beams without the ... optical clarity and natural durability (9 mohs) make it ...
(Date:6/18/2013)... DuPont welcomes 48 of the nation’s finest ... AgriScience Teachers Ambassador Academy this week (NATAA) at the ... , The NATAA “Ag Academy” is a professional ... project of the National FFA Foundation and ... The highly recommended agriscience teachers, who are participating ...
(Date:6/18/2013)... , June 18, 2013 ... using the company,s  proprietary AMCA Guided Bone Regeneration (GBR) Dental ... implants. A common problem encountered when patients have ... of sufficient bone volume to house the implant. Consequently there ... bone substitute until the natural bone regenerates. The bone substitute ...
(Date:6/18/2013)... 18, 2013  regulated information — Global biopharmaceutical company ... today announced the launch of a new Pledge campaign ... The Pledge empowers the millions of ... make a personal commitment to demand more: greater understanding ... team and additional partial-onset seizure control.  More information is ...
Breaking Biology Technology:Swiss Jewel Introduces the Crown Jewels of Fiber-Optic Connectors 2DuPont Sponsors National AgriScience Ambassador Academy 2DuPont Sponsors National AgriScience Ambassador Academy 3RegeneCure Starts Clinical Study Using Polymeric Bone Stimulating Membrane for Dental Implants 2RegeneCure Starts Clinical Study Using Polymeric Bone Stimulating Membrane for Dental Implants 3Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 2Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 3Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 4Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 5Professional Golfer Jeff Klauk Tees Off New Pledge Campaign for People Living with Epilepsy 6
... , , BOTHELL, Wash., ... BLFS), a leading developer, manufacturer, and marketer of biopreservation ... Sigma-Aldrich(R) will distribute the Company,s proprietary HypoThermosol and CryoStor ... distribution agreement. , , (Logo: ...
... , , , ... Sept. 14 Tobira Therapeutics Inc., a clinical stage ... the treatment of life-threatening and life-altering infectious diseases, today ... multiple-dose randomized study of TBR-652 in sixty healthy volunteers. ...
... ATLANTA, Sept. 14 CryoLife, Inc. (NYSE: ... and cardiovascular tissue processing company, announced today that it is scheduled ... the Grand Hyatt New York in New York City. , ... of CryoLife, Inc., will present Monday, September 21 at 2:00 p.m., ...
Cached Biology Technology:BioLife Solutions Announces HypoThermosol(R) and CryoStor(TM) Distribution Agreement With Sigma-Aldrich 2BioLife Solutions Announces HypoThermosol(R) and CryoStor(TM) Distribution Agreement With Sigma-Aldrich 3Tobira Therapeutics Inc. Announces Phase I Pharmacokinetic Data of TBR-652 for the Treatment of HIV 2CryoLife to Present at UBS Global Life Sciences Conference 2
Immunogen: Synthetic peptide: N(171) H G F L S A D Q QL I K(183) Storage: -20 C, Avoid Freeze/Thaw Cycles...
... Chicken polyclonal to Uridine Phosphorylase 1 ( ... Antigen: Synthetic peptide: MAATGANAEK ... PGRDYPNICA GTDRYAMYK, corresponding to amino acids 1-99 ... Entrez Gene ID: 7378 ...
Request Info...
Lingo-1 (K-13)...
Biology Products: