Navigation Links
DNA nanotechnology breakthrough offers promising applications in medicine
Date:3/17/2010

This release is available in French.

A team of McGill Chemistry Department researchers led by Dr. Hanadi Sleiman has achieved a major breakthrough in the development of nanotubes tiny "magic bullets" that could one day deliver drugs to specific diseased cells. Sleiman explains that the research involves taking DNA out of its biological context. So rather than being used as the genetic code for life, it becomes a kind of building block for tiny nanometre-scale objects.

Using this method, the team created the first examples of DNA nanotubes that encapsulate and load cargo, and then release it rapidly and completely when a specific external DNA strand is added. One of these DNA structures is only a few nanometres wide but can be extremely long, about 20,000 nanometres. (A nanometre is one-10,000th the diameter of a human hair.)

Until now, DNA nanotubes could only be constructed by rolling a two-dimensional sheet of DNA into a cylinder. Sleiman's method allows nanotubes of any shape to be formed and they can either be closed to hold materials or porous to release them. Materials such as drugs could then be released when a particular molecule is present.

One of the possible future applications for this discovery is cancer treatment. However, Sleiman cautions, "we are still far from being able to treat diseases using this technology; this is only a step in that direction. Researchers need to learn how to take these DNA nanostructures, such as the nanotubes here, and bring them back to biology to solve problems in nanomedicine, from drug delivery, to tissue engineering to sensors," she said.

The team's discovery was published on March 14, 2010 in Nature Chemistry. The research was made possible with funding from the National Science and Engineering Research Council and the Canadian Institute for Advanced Research.


'/>"/>

Contact: William Raillant-Clark
william.raillant-clark@mcgill.ca
514-398-2189
McGill University
Source:Eurekalert

Page: 1

Related biology news :

1. Vigilance needed in nanotechnology
2. Engineers explore environmental concerns of nanotechnology
3. Conference to discuss future of nanotechnology enabled sensors
4. Novel nanotechnology heals abscesses caused by resistant staph bacteria
5. Step forward for nanotechnology: Controlled movement of molecules
6. Nanotechnology and synthetic biology: What does the American public think?
7. New DNA test uses nanotechnology to find early signs of cancer
8. Singapore nanotechnology combats fatal brain infections
9. University awarded £1.7M to develop nanotechnology for use in health care
10. Nanotechnology holds promise for STD drug delivery
11. Donation for new Center for Pharmaceutical Nanotechnology and Nanotoxicology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2017)... robotic gym for the rehabilitation and functional motor sense evaluation of lower ... . The first 30 robots will be available from June in ... The technology was developed and patented at the IIT laboratories and has ... to a 10 million euro investment from entrepreneur Sergio Dompè. ... ...
(Date:5/6/2017)... 5, 2017 RAM Group , ... new breakthrough in biometric authentication based on a ... properties to perform biometric authentication. These new sensors are ... created by Ram Group and its partners. This sensor ... supply chains and security. Ram Group is a ...
(Date:4/18/2017)...  Socionext Inc., a global expert in SoC-based imaging and computing ... M820, which features the company,s hybrid codec technology. A demonstration utilizing ... Inc., will be showcased during the upcoming Medtec Japan at Tokyo ... Las Vegas Convention Center April 24-27. ... Click here for an image ...
Breaking Biology News(10 mins):
(Date:6/22/2017)... Ca (PRWEB) , ... June 22, 2017 , ... The ... It took 20 years until the first data on cross-contamination of human cell lines ... has been an increasing issue in cell culture labs and is associated with dramatic ...
(Date:6/20/2017)... ... 20, 2017 , ... CTNext , Connecticut’s go-to resource ... a Higher Education Entrepreneurship Advisory Committee to implement the recommendations of the master ... representatives from 35 higher education institutions across the state over the past six ...
(Date:6/20/2017)... , June 20, 2017  Kibow Biotech Inc., a ... announce the issuance of a new patent covering a ... by the U.S. Patent and Trademark Office on May ... of the Buzz of Bio award in 2014 in ... to developing non-drug approaches to chronic disease. Renadyl™, the ...
(Date:6/20/2017)... ... June 20, 2017 , ... GigaGen Inc ., a ... repertoires, announces launch of its new Surge(TM) Discovery service at the ... GigaGen, will present on Surge at the conference. , Surge is the new, ...
Breaking Biology Technology: