Navigation Links
DNA engine observed in real-time traveling along base pair track
Date:2/6/2011

Kyoto, Japan -- In a complex feat of nanoengineering, a team of scientists at Kyoto University and the University of Oxford have succeeded in creating a programable molecular transport system, the workings of which can be observed in real time. The results, appearing in the latest issue of Nature Nanotechnology, open the door to the development of advanced drug delivery methods and molecular manufacturing systems.

Resembling a monorail train, the system relies on the self-assembly properties of DNA origami and consists of a 100 nm track together with a motor and fuel. Using atomic force microscopy (AFM), the research team was able to observe in real time as this motor traveled the full length of the track at a constant average speed of around 0.1 nm/s.

"The track and motor interact to generate forward motion in the motor," explained Dr. Masayuki Endo of Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS). "By varying the distance between the rail 'ties,' for example, we can adjust the speed of this motion."

The research team, including lead author Dr. Shelley Wickham at Oxford, anticipates that these results will have broad implications for future development of programable molecular assembly lines leading to the creation of synthetic ribosomes.

"DNA origami techniques allow us to build nano- and meso-sized structures with great precision," elaborated iCeMS Prof. Hiroshi Sugiyama. "We already envision more complex track geometries of greater length and even including junctions. Autonomous, molecular manufacturing robots are a possible outcome."


'/>"/>

Contact: Yutaka Iijima
yutaka-iijima@icems.kyoto-u.ac.jp
Institute for Integrated Cell-Material Sciences, Kyoto University
Source:Eurekalert

Page: 1

Related biology news :

1. Purdue team creates engineered organ model for breast cancer research
2. Enzyme Engineering XXI
3. Extracting cellular engines may aid in understanding mitochondrial diseases
4. The ecosystem engineer: Research looks at beavers role in river restoration
5. Seaweed as biofuel? Metabolic engineering makes it a viable option
6. UCLA bioengineers discover how particles self-assemble in flowing fluids
7. MGH researchers develop faster method of engineering zinc-finger nucleases
8. UVic biomedical engineer outsmarts HIV
9. Virginia Tech engineer identifies new concerns for antibiotic resistance, pollution
10. In the lab, engineers novel liquid provides a solid fix for broken bones
11. Rensselaer Polytechnic Institute professor Georges Belfort wins biochemical engineering award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... available in German . ... objects; they also provide us with a continuous stream of ... fall or sit still in a car the world ... our retinas. Seemingly without effort, our brain calculates self-motion from ... position and a steady gaze during our own movements. Together ...
(Date:4/17/2014)... House honored Clemson professor Rajendra Singh Thursday as ... promote and expand solar deployment in the residential, ... Houser Banks Professor of Electrical and Computer Engineering ... is considered a local hero leading the charge ... opportunity in solar power and driving policy changes ...
(Date:4/17/2014)... hit on a novel method to help kidney ... most effective treatment possible., Kidney stones represent a ... world. If left untreated, apart from being particularly ... other complications. In many patients treated successfully, stone ... effective pathological approach to diagnosis and treatment needs ...
Breaking Biology News(10 mins):How vision makes sure that little fish do not get carried away 2How vision makes sure that little fish do not get carried away 3How vision makes sure that little fish do not get carried away 4White House honors Clemson professor as 'Champion of Change' for solar deployment 2
... to Research Careers) Program has announced the travel award ... Course in Immunology at the Seaport World Trade Center, ... These awards are meant to promote the entry ... mainstream of the basic science community and to encourage ...
... gas seeping from the melting Arctic ice cap told Jeff ... permafrost thaws, there is a release of methane, a powerful ... figuring out how much, said Chanton, the John W. Winchester ... team whose findings were published in the respected journal ...
... long-held misconceptions about oil production in algae, scientists at the ... up the microbes, overall metabolism by feeding them more carbon ... findings published online in the journal Plant and ... to new ways to turn photosynthetic green algae into tiny ...
Cached Biology News:Study: Seeping Arctic methane has serious implications for Florida coastline 2Carbon is key for getting algae to pump out more oil 2Carbon is key for getting algae to pump out more oil 3
(Date:1/14/2014)... WESTBOROUGH, Mass. , Jan. 14, 2014  RXi ... on discovering, developing and commercializing innovative therapies addressing ... announced that it received the Notice of Allowance ... on its unique self-delivering RNAi compounds (sd-rxRNA®), for ...
(Date:1/14/2014)... 14, 2014   Kinaxis ®, provider of RapidResponse ®, ... and operations planning ( S&OP ) service, is proud to ... which will be held at the Hilton San Diego Bayfront, ... customer Elisabeth Kaszas , Director of Supply Chain at ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Kerr Corporation, a ... video and additional how-to information about dual arch impressions on ... with Dual Arch Impressions,” the blog entry serves up a ... and houses a step-by-step demonstration by Dr. David Little as ...
(Date:1/14/2014)... 2014 Independent publisher Bitingduck Press, with ... Canada, has big ideas for 2014 in production and ... are to produce high-quality, low-cost, DRM-free ebooks and to ... , The first major development will be bookstore ...
Breaking Biology Technology:RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2Bitingduck Press Looks Forward to 2014 With Multimedia E-books 2
... VANCOUVER, March 17 /PRNewswire-FirstCall/ - Angiotech Pharmaceuticals,Inc. (NASDAQ: ... pharmaceutical and,medical device company, is scheduled to participate ... which is being held March,18-20 in Miami Beach, ... Chief Executive Officer,is scheduled to present on Thursday, ...
... Research Reveals Imaging with Siemens, Artis zeego ... Chemoembolization Procedures for Interventional Radiologists, WASHINGTON, ... the,Society of Interventional Radiology,s (SIR) Annual Scientific ... of a new interventional imaging,capability using advanced ...
... Mercury Therapeutics,Inc. (MTI), a company that ... drugs, announces that it has retained Marquant ... its strategic and partnering,opportunities, with the aim ... This appointment follows a significant amount of ...
Cached Biology Technology:New Robotic Imaging Technology Holds Promise of Improved Cancer Care 2New Robotic Imaging Technology Holds Promise of Improved Cancer Care 3New Robotic Imaging Technology Holds Promise of Improved Cancer Care 4Mercury Therapeutics, Inc: Marquant Appointed to Advise on Strategic and Partnering Opportunities 2Mercury Therapeutics, Inc: Marquant Appointed to Advise on Strategic and Partnering Opportunities 3
BD BioCoat Poly-D-Lysine 60 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of poly-D-lysine....
... Ciphergens ProteinChip System, Series 4000 incorporates the ... researchers and biologists in biomarker research. The ... fastest route for converting biomarker discoveries to ... The Series 4000 is designed to fit ...
Gelatin 100 mm Culture Dishes...
BD Primaria 100 mm Cell Culture Dish, surface-modified polystyrene for enhanced cell culture. (200/ca) Packaging: 20 / sleeve, 200 / case ...
Biology Products: