Navigation Links
DBS studies show how brain buys time for tough choices
Date:9/25/2011

[decision] conflict," he said. "It is responsive to the circumstances that the signals on top of the scalp are responsive to, and in highly similar frequency bands and time ranges."

A mathematical model for analyzing the measurements of accuracy and response time confirmed that the elevated neural activity and the extra time people took to decide was indeed evidence of effortful deliberation.

"It was not that they were waiting without doing anything," said graduate student Thomas Wiecki, the paper's second author. "They were slower because they were taking the time to make a more informed decision. They were processing it more thoroughly."

The results have led the researchers to think that perhaps the different brain regions communicate by virtue of these low-frequency signals. Maybe the impulsivity side effect of DBS could be mitigated if those bands could remain unhindered by the stimulator's signal. Alternatively, Wiecki said, a more sophisticated DBS system could sense that decision conflict is underway in the mPFC and either temporarily suspend its operation until the decision is made, or stimulate the STN in a more dynamic way to better mimic intact STN function.

These are not trivial ideas to foist upon DBS engineers, but by understanding the mechanics underlying the side effect and in healthy unhindered decision making the researchers say they now have a target to consider.


'/>"/>

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. New studies find global warming will have significant economic impacts on Florida coasts
2. NIHs Genes, Environment and Health Initiative adds 6 studies
3. 6 environmental research studies reveal critical health risks from plastic
4. NIAID funds studies of how SARS and bird flu evade antiviral responses
5. Drug-embedded microparticles bolster heart function in animal studies
6. ASU researchers receive NIH awards for studies of malaria and emergent disease
7. Studies of small water fleas help ecologists understand population dynamics
8. MSU researcher studies ties between cholesterol drugs, muscle problems
9. UI researchers help to improve carbon measurements in global climate studies
10. Studies on imaging and tracking transplanted cells
11. To improve forecasting earthquakes, NJIT mathematician studies grains
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... -- Earlier this year Donald Spector , Chairman of ... the most prolific inventors in the world, got a ... to third party agencies. Spector envisioned this technology even ... earliest known patents in this area. Now major technology ... care, elder care and hospital applications. This technology has ...
(Date:11/21/2014)... Wash. , Nov. 20, 2014 C-Labs ... for the Internet of Things (IoT), today announced the ... of chief operating officer. Previously a strategic advisor to ... finance, and operations. Mr. Traynor is based out of ... . He reports to Chris Muench , Chief ...
(Date:11/18/2014)... 18, 2014  The Secure Identity & Biometrics ... jointly announce the formation of The Airport Entry ... Identity and Biometric Entry and Exit Solutions ... official support from BORDERPOL, the international non-profit organization ... provide expertise regarding border security, traveler and migration ...
Breaking Biology News(10 mins):Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 4C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3
... studies reveal that voting decisions are more associated ... a politician,s appearance than to positive ones, says ... of Technology (Caltech), Scripps College, Princeton University, and ... particularly true when voters have little or no ...
... beware. Chances are your male partner is on your ... even when you have kept to the straight and ... constant vigilance, women may be better than men at ... in Richmond and colleagues gave 203 young heterosexual couples ...
... sustainability expert Deane Evans will provide an introduction to the basics of ... seminar, open to the public, at NJIT. The talk, set ... a review of the status of the NJ schools, construction program. ... Evans, a registered architect, is executive director ...
Cached Biology News:Caltech-led researchers find negative cues from appearance alone matter for real elections 2Caltech-led researchers find negative cues from appearance alone matter for real elections 3Caltech-led researchers find negative cues from appearance alone matter for real elections 4Men are better at detecting infidelities 2
(Date:12/22/2014)... The American Journal of Hematology/Oncology, ... reviews and editorials addressing developments and pathways related ... a provocative article exploring the role of follicle-stimulating ... treatment of prostate cancer. , The article ... possibility that there could be a connection to ...
(Date:12/22/2014)... Fertility Associates of Memphis has announced a ... a network of more than 20 contributing fertility ... fast access to a national pool of frozen ... Associates of Memphis is the only fertility clinic in ... Dr. William Kutteh , director of Fertility Associates ...
(Date:12/19/2014)... Charm Sciences is pleased to announce ... of Aflatoxin M1 in raw commingled milk is the ... validation. The peer reviewed report of the validation by ... Agricultural and Fisheries Research (ILVO-T&V) has been published by ... the most toxic aflatoxin and a known carcinogen, can ...
(Date:12/19/2014)... 2014 Naurex Inc., a biopharmaceutical company leveraging ... of the central nervous system, today announced that ... will present at the 33 rd annual J.P. ... at 3:00 p.m. PST on Tuesday, January 13, 2015, ... Francisco, Calif. About Naurex ...
Breaking Biology Technology:Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 2Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 3Prostate Cancer Experts Dissect the Role of Follicle-stimulating Hormone in the Development, Progression and Potential Treatment of Prostate Cancer 4Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 3Charm Sciences Achieves Independent Validation of First 15 Minute Quantitative Screening Method for Aflatoxin M1 2Naurex to Present at 33rd Annual J.P. Morgan Healthcare Conference 2
... May 17 ViroPharma Incorporated (Nasdaq: VPHM ) ... [Human]), its product proven to prevent attacks of hereditary angioedema (HAE), ... needle-less reconstitution system. This simple-to-use reconstitution device and accompanying training materials ... , , ...
... to Highlight Latest Biomedical Licensing Opportunities , ... KANSAS CITY, Mo. , ... not-for-profit Kauffman Innovation Network, Inc., today announced that it is continuing ... Health Network (UHN), a group of leading research hospitals and institutes ...
... 17 /PRNewswire-FirstCall/ - Aeterna Zentaris Inc. ( AEZS, ... specialized in oncology and endocrinology, today announced that it ... designation from the Committee for Orphan Medicinal Products (COMP) ... for the treatment of ovarian cancer. AEZS-108, the Company,s ...
Cached Biology Technology:ViroPharma Introduces New Reconstitution System for Cinryze™ (C1 Esterase Inhibitor [Human]) 2ViroPharma Introduces New Reconstitution System for Cinryze™ (C1 Esterase Inhibitor [Human]) 3ViroPharma Introduces New Reconstitution System for Cinryze™ (C1 Esterase Inhibitor [Human]) 4ViroPharma Introduces New Reconstitution System for Cinryze™ (C1 Esterase Inhibitor [Human]) 5The iBridge Network Adds Toronto's University Health Network as First Canadian Partner 2The iBridge Network Adds Toronto's University Health Network as First Canadian Partner 3Aeterna Zentaris Receives Positive Opinion for Orphan Medicinal Product Designation for AEZS-108 for the Treatment of Ovarian Cancer from the Committee for Orphan Medicinal Products of the European Medicines Agency 2Aeterna Zentaris Receives Positive Opinion for Orphan Medicinal Product Designation for AEZS-108 for the Treatment of Ovarian Cancer from the Committee for Orphan Medicinal Products of the European Medicines Agency 3