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Critical element that improves vascular function in postmenopausal women found
Date:2/14/2012

at suggests estrogen may benefit arteries by maintaining BH4 levels," Moreau said. "Having adequate BH4 levels would result in increased nitric oxide and decreased free radicals, promoting vasodilatation and reducing arterial stiffness."

It has been long known that menopause has significant impacts on women's health.

"Menopause is like an accelerated aging process," Moreau said."When women hit menopause you see this dramatic decline in arterial health." Moreau's discovery of the key role BH4 plays in this process sheds more light on the decline in arterial health and why it may not be inevitable.

"As we identify the causes of the vascular health decline we can next intervene with appropriate therapeutic strategies including exercise, diet and/or hormone therapy," she said. "Heart disease is the number one killer of men and women but it is underappreciated in women who need a better understanding of cardiovascular health."


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Contact: David Kelly
david.kelly@ucdenver.edu
303-315-6374
University of Colorado Denver
Source:Eurekalert

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