Navigation Links
Creating an 'electronic nose' to sniff out tuberculosis from a patient's breath

A new hand-held device called the Electronic Nose, which has the potential to diagnose tuberculosis (TB) in symptomatic patients, was awarded a $950,000 grant from Grand Challenges Canada and the Bill & Melinda Gates Foundation today to support further development and testing of this ground-breaking technology.

The funding will help determine whether the Electronic Nose is able to detect TB immediately and non-invasively from the patient's breath, in order to replace time-consuming testing with sputum.

It is estimated that up to 400,000 lives a year can be saved in the developing world by early diagnosis, immediate treatment and reduced transmission of this killer disease.

TB has been all but eliminated in the developing world, but in poor countries it claims close to 1.7 million lives yearly and is second only to HIV/AIDs as the world's most deadly infectious disease.

"This important discovery is testimony to the power of innovation to save lives," said Dr. Peter Singer, CEO of Grand Challenges Canada. "Diagnosing TB and other pulmonary disease simply by testing a patient's breath is a bold idea with potentially big impact."

The development of the Electronic Nose is a collaboration between the International Centre for Genetic Engineering and Biotechnology in New Delhi, India, and Next Dimension Technologies in California. The New Delhi innovators are working with sensors developed in California to track biomarkers in the breath. Those biomarkers may hold promise to identify TB disease, leading to earlier diagnosis and improved patient treatment.

"We hope to take the concept of the Electronic Nose to the next level by developing and testing a prototype of the hand-held, battery-powered device," said Prof. Virander Chauhan and Dr. Ranjan Nanda, lead researchers. "Our goal is to make the Electronic Nose widely available in poor, remote areas where tuberculosis often breeds and spreads, devastating so many lives."

Scientists say Electronic Noses could also be created for early detection of lung cancer and pneumonia, based on signature biomarkers of that disease detectable in a patient's breath.

"Grand Challenges Explorations aims to tackle critical health and development challenges by funding creative, high-risk concepts that show the greatest potential for impact," said Chris Wilson, Director of Global Health Discovery at the Bill & Melinda Gates Foundation. "With this additional phase of funding, we're excited to move the most promising projects closer to products that could ultimately save millions of lives."

"Imagine detecting tuberculosis through a person's breath and the number of people who can be saved," said Joseph L. Rotman, Chair of Grand Challenges Canada. "We are pleased to support this discovery and, through Grand Challenges Canada's Integrated Innovation approach, to ensure rapid patient utilization and commercialization, so that the Electronic Nose is available, cost-effectively."

Contact: Terry Collins
McLaughlin-Rotman Centre for Global Health

Related biology news :

1. Better beer: College team creating anticancer brew
2. Argonne scientists discover possible mechanism for creating handedness in biological molecules
3. Creating ideal neural cells for clinical use
4. Marine microbes creating green waves in industry
5. Marine microbes creating green waves in industry
6. Stimulus-funded university research addressing issues from climate change to cancer, creating jobs and training a new generation of scientists
7. Melting tundra creating vast river of waste into Arctic Ocean
8. Scientists are first to unlock the mystery of creating cultured pearls from the queen conch
9. Forest deal at Copenhagen must avoid creating carbon refugees
10. VAI researchers find long awaited key to creating drought resistant crops
11. Creating a dream breed
Post Your Comments:
Related Image:
Creating an 'electronic nose' to sniff out tuberculosis from a patient's breath
(Date:6/22/2016)... 2016   Acuant , the leading ... has partnered with RightCrowd ® to ... Management, Self-Service Kiosks and Continuous Workforce Assurance. ... functional enhancements to existing physical access control ... with an automated ID verification and authentication ...
(Date:6/21/2016)... British Columbia , June 21, 2016 /PRNewswire/ ... appointed to the new role of principal product ... been named the director of customer development. Both ... NuData,s chief technical officer. The moves reflect NuData,s ... teams in response to high customer demand and ...
(Date:6/16/2016)... 2016 The global ... reach USD 1.83 billion by 2024, according to ... Technological proliferation and increasing demand in commercial buildings, ... drive the market growth.      (Logo: ... development of advanced multimodal techniques for biometric authentication ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... June 27, 2016  Alex,s Lemonade Stand Foundation (ALSF), ... it will open a state-of-the-art bioinformatics lab, using ,big ... This announcement comes as Liz Scott , co-executive ... Cancer Moonshot Summit in Washington, D.C. ... a participant and advocate of pediatric cancer research and ...
(Date:6/27/2016)... June 27, 2016  Global demand for enzymes ... through 2020 to $7.2 billion.  This market includes ... cleaning products, biofuel production, animal feed, and other ... and biocatalysts). Food and beverages will remain the ... increasing consumption of products containing enzymes in developing ...
(Date:6/27/2016)... ON , June 27, 2016 /PRNewswire/ - BIOREM Inc. ... has been advised by its major shareholders, Clean Technology ... United States based venture capital ... shares of Biorem (on a fully diluted, as converted ... the disposition of their entire equity holdings in Biorem ...
(Date:6/27/2016)... June 27, 2016  Sequenom, Inc. (NASDAQ: ... healthier lives through the development of innovative products and ... the United States denied its petition ... claims of Sequenom,s U.S. Patent No. 6,258,540 (",540 Patent") ... established by the Supreme Court,s Mayo Collaborative Services v. ...
Breaking Biology Technology: