Navigation Links
Cow vaccines go vroom

In much of Africa, a herd of cattle is more than just cows. It's a savings account, protein store, dowry, funeral fund, symbol of wealth, and hedge against drought. For many smallholder farmers, the loss of even a single cow to disease can spell ruin.

Yet a grievous number of cattle in sub-Saharan Africa get sick: one estimate puts annual losses from disease at $40 billion, some twenty-five percent of the total value of livestock production in the region.

John Barlow, professor of animal sciences at the University of Vermont, thinks the cows in the university's research herd may be able to help.

"Many cattle diseases in sub-Saharan Africa might be prevented if we had better vaccines," he says, "but the way we have traditionally created vaccines is expensive and takes a lot of time."

That's why he's leading an international project that aims to better understand the molecular workings of cow immune systems -- and accelerate the development of vaccines for two critical cattle diseases: East Coast fever and foot-and-mouth disease.

Barlow and his colleagues in Kenya, Denmark and at the U.S. Department of Agriculture are supported by a new three-year grant from the National Science Foundation.

"In the first year, we will be studying the cattle in the University of Vermont herd to understand the diversity of their immune function genes," Barlow says.

Then, applying this knowledge, the team will use a new technology that has been accelerating human vaccine development, but, until now, hasn't been applied to cows: so-called MHC tetramers. These synthetic molecules allow researchers to quickly get a view of what proteins in the invading virus or parasite are likely to spark a strong immune response in the host animal.

"These proteins are the key vaccine candidates," says Barlow -- and can be tested in lab cell lines.

The MHC -- or "major histocompatibility complex" -- is a large family of g

Contact: Joshua Brown
University of Vermont

Page: 1 2 3

Related biology news :

1. Scientists use computer algorithms to develop seasonal flu vaccines
2. New bacterial signaling molecule could lead to improved vaccines
3. Prescription drug could boost effects of vaccines for HIV and other diseases
4. Vaccines preventing pneumococcal disease protect African children with sickle-cell disease
5. GEN reports on the promise of DNA vaccines
6. Major breakthrough may pave the way for therapeutic vaccines
7. Bug barcode readers hold out promise of universal vaccines
8. Pitt researchers find promising candidate protein for cancer prevention vaccines
9. Study shows cancer vaccines led to long-term survival for patients with metastatic melanoma
10. Princeton teams analysis of flu virus could lead to better vaccines
11. New evidence explains poor infant immune response to certain vaccines, says MU researcher
Post Your Comments:
(Date:3/17/2015)... March 17, 2015 Emotient, the leader ... today announced general availability of Emotient Analytics ... the analysis of facial expressions. The system analyzes ... content, products and services. It delivers audience response ... sentiment - as derived from facial evidence of ...
(Date:3/12/2015)... Va. , March 12, 2015 IriTech, ... and a member of the Texas Instruments Design Network, ... Naidu has demonstrated its IriShield USB MK2120U device ... scanning facility for pension distribution. The ... assembled to be marketed in India ...
(Date:3/12/2015)... , March 12, 2015 WHEN:Tuesday, March ... Registration here: . SPEAKERS: , Frost ... SeshagiriPhoto - Biometric ... to compete in several different markets and industries. ... currently witnessing an uptrend. Join ...
Breaking Biology News(10 mins):New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 2New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 3New Emotient Web Service Measures Audience Response Using On-Demand Facial Expression Analysis 4Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 2Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 3Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 2Biometrics Key to Future Growth in Healthcare, Retail and Financial Markets 3
... Institute of Food Research, which is strategically funded ... proteins that destroy bacterial cells to combat potentially ... specifically target certain bacteria, and IFR has been ... a common and dangerous source of hospital-acquired infections. ...
... to the puzzle of scaling how patterns stay in ... develops. In a new study appearing in Current Biology, Institute ... Danny Ben-Zvi of the Molecular Genetics Department have shown how ... the vein structure stays perfectly proportioned and their findings ...
... Male adult helminthomorph millipedes usually have one or ... into sexual appendages. These specialized gonopods are used as ... transfer sperm. New research published in BioMed Central,s open ... in detail at millipede development and the internal reorganization ...
Cached Biology News:Tuning natural antimicrobials to improve their effectiveness at battling superbugs 2Scale models 2The secret life of millipedes 2
(Date:3/25/2015)... IL (PRWEB) March 25, 2015 ... Symmetry® Top-Loading Balances and Analytical Balances to get ... expanded line of weighing balances from the trusted ... Toploading Balances increase your efficiency by providing ... variety of samples. Weighing modes include parts counting, ...
(Date:3/25/2015)... CORAL SPRINGS, Fla. , March 25, 2015 ... (HIT) strategy and management consulting firm, has launched ... reference publication to simplify tracking of ePrescribing regulatory ... "The ePrescribing regulatory landscape continues to ... offerings to deliver what the industry, and ultimately ...
(Date:3/25/2015)... HAGUE, Netherlands , March 25, 2015  EndoStim ... for chronic gastro-esophageal reflux disease (GERD) in the March ... Surgery . 2015; 157(3):556-567 ], establishing the long term ... The study included 25 patients with severe GERD ... prescribed daily proton pump inhibitor (PPI) medication for an ...
(Date:3/25/2015)... NEW YORK , March 25, 2015 ... has released today version 4 of Face2Gene, ... Novel Analysis from computers, as well as mobile devices. ... patterns of human malformations to present comprehensive and up-to-date ... the Annual Clinical Genetics Meeting, ACMG 2015, in ...
Breaking Biology Technology:New Economical Top-Loading and Analytical Symmetry Balances from Cole-Parmer 2Point-of-Care Partners Launches the ePrescribing State Law Capsule 2EndoStim LES Stimulation therapy demonstrates long term safety and efficacy results in treating reflux patients 2EndoStim LES Stimulation therapy demonstrates long term safety and efficacy results in treating reflux patients 3FDNA Releases a Multi-Platform Version of Face2Gene, a Genetic Search and Reference Solution at ACMG 2015 2
... Ltd (ASX: PXS; Nasdaq: PXSL) announced today that ... fibrosis demonstrated excellent lung,function improvement following three months ... current marketed product rhDNase(1). The,improvement in lung function ... a previous study following two weeks of treatment., ...
... Therapeutics Corporation,today announced the appointment of Bruce A. ... member of its Board of Directors. Mr. Peacock ... LLC. Previously, he served,as the CEO or was ... several,successful entrepreneurial healthcare companies operating in therapeutic,diagnostic and ...
... 2008 In this report,entitled "MedPredict Thought ... experts discuss the key controversies,surrounding development of ... the,biopharmaceutical industry is underestimating the size of ... panel, there are a number of factors,stymieing ...
Cached Biology Technology:Cystic Fibrosis Trial In Children Returns Positive Data 2Cystic Fibrosis Trial In Children Returns Positive Data 3Cystic Fibrosis Trial In Children Returns Positive Data 4Alba Therapeutics Announces Appointment of Bruce A. Peacock as its Chief Executive Officer 2New MedPredict Report Suggests Market for Alcoholism Therapies is Underestimated 2
... mixture excluding l-[U-14C]methionine, 1.85 MBq, 50 ... sterilized. > 1.85 GBq/mg atom ... Mixture of Ala, Arg, Asp, ... Phe, Pro, Ser, Thr, Tyr and ...
The Spheroplast Kit contains qualified reagents for the preparation of yeast spheroplasts. The reagents have been optimized for use with Pichia pastoris and are guaranteed to generate 70% spheroplast...
Biology Products: