Navigation Links
Covering the bases: Quantum effect may hold promise for low-cost DNA sequencing, sensor applications
Date:3/22/2009

A ghostly property of matter, called quantum tunneling, may aid the quest for accurate, low-cost genomic sequencing, according to a new paper in Nature Nanotechnology Letters by Stuart Lindsay and his collaborators at the Biodesign Institute of Arizona State University. Tunneling implies that a particle, say an electron, can cross a barrier, when, according to classical physics, it does not have enough energy to do so.

Unraveling the DNA sequences of the human genome a decade ago was a remarkable achievement. Today, the task of sequencing some 3 billion chemical base pairs of the genomeenough information to fill a 20-volume encyclopediaremains a daunting challenge, thus far accomplished largely through brute force means. Such methods are typically slow and extravagantly expensive, (though costs have dropped considerably from the initial sequencing of the human genome, which took 11 years at a cost of $1 billion.)

Bringing the power of DNA sequencing to every individual will require new, affordable technologies to help mine the wealth of information DNA can provide concerning morphology, hereditary traits and predisposition to disease.

Various techniques for sequencing DNA have been used to determine the identities of the four nucleotide basesadenine, thymine, cytosine and guaninewhich make up the ladder rungs of the DNA's double helical structure. Most of these require snipping DNA into hundreds of thousands of short fragments, unzipping the helix and reading a few hundred to a few thousand bases at a time. Finally, all of the information from the DNA pieces is reassembled into a picture of the complete genome, with the help of massive computing power.

ASU Regents' Professor and Carson Presidential Chair of Physics and Chemistry, Stuart Lindsay, who also directs the Biodesign Institute's Center for Single Molecule Biophysics, summarizes one of the chief physical obstacles to more efficient identification of DNA
'/>"/>

Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-313-2010
Arizona State University
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Discovering the secret code behind photosynthesis
2. Uncovering secrets of life in the ocean
3. Deep biosphere research points to new methods for recovering petroleum
4. Discovering drugs, biofuels in tropical seas
5. Recovering from a mass extinction
6. MSU researcher helps develop computer game for Ugandan children recovering from cerebral malaria
7. Rice eyes risks of quantum dots
8. New technique is quantum leap forward in understanding proteins
9. Strained quantum dots show new optical properties
10. Study shows quantum dots can penetrate skin through minor abrasions
11. Europe gets together to harness quantum physics
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Covering the bases: Quantum effect may hold promise for low-cost DNA sequencing, sensor applications
(Date:4/2/2015)... , April 2, 2015 ... Q1 2015 attributed to somewhat higher than 125 MSEK. ... the year-end report 2014 that revenues for Q1 2015 ... the company reported for Q4 2014. The operating result ... be negative. The complete interim report will as previously ...
(Date:4/1/2015)... BOSTON , April 1, 2015   Medisafe ... 1.5 million users across iOS and ... has begun integrating biofeedback into the platform to allow ... health outcomes. For the first time, patients will be ... missing a dose impacts important biometrics, such as glucose ...
(Date:3/30/2015)... and Markets ( http://www.researchandmarkets.com/research/lc9bnl/global_gesture ) has announced ... in Automotive Sector 2014-2018" report to their offering. ... market in Automotive Sector to grow at a CAGR ... recognition is the ability of a device to identify ... recognition technology can be 2D-based or 3D-based. It uses ...
Breaking Biology News(10 mins):Fingerprint Cards Revises Revenues for Q1 2015 2Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2
... by the North Central Cancer Treatment Group (NCCTG) reports that ... recurrent brain cancer slowed tumor growth in more than one-third ... research team also developed a screening technique to help predict ... researchers will present these findings at the 2005 American Society ...
... by camouflage in the same way that humans are deceived, ... idea that bold contrasting colours help to break-up the body's ... as the First World War. And in biology this idea ... insects such as moths conceal themselves from predators, shaping the ...
... Animal geneticist Harvey D. Blackburn is responsible for collecting ... mainly semen and embryos -- to make sure there's ... Much of his collection deals with important livestock such ... of the collections Blackburn, who is the coordinator of ...
Cached Biology News:'Smart drug' targets deadly brain cancer 2'Smart drug' targets deadly brain cancer 3Making Sure Sacred Sheep Don't Become Extinct 2
(Date:4/17/2015)... 17, 2015  Guggenheim Securities, the investment banking and ... hiring of William Tanner as a Managing ... Tanner will start work at Guggenheim in May 2015 ... office. "Bill brings a wealth of biotech ... experienced and highly acclaimed healthcare team," said Matthew ...
(Date:4/17/2015)... WI (PRWEB) April 17, 2015 ... sales and marketing support for the powerful Orthogonal ... the Chemical Genomics Center at the Lankenau Institute ... LCGC’s mission is to measurably improve successful drug ... HTS, by offering rare, drug-like libraries available nowhere ...
(Date:4/16/2015)... 2015 Cytokinetics, Incorporated (Nasdaq: CYTK) announced ... results on Thursday, April 30, 2015 at 4:00 PM ... host a conference call at 4:30 PM Eastern Time ... outlook for the future. , The conference call will ... homepage and in the Investor Relations section of Cytokinetics’ ...
(Date:4/16/2015)... Regis Technologies looks forward to being part ... (AACR) annual meeting. Regis will exhibit at this year's ... 18, in Philadelphia and running through April 22, 2015. ... oldest and largest organization focused on cancer research. It ... with survivors to promote awareness and research funding. ...
Breaking Biology Technology:Guggenheim Securities Hires Biotech Analyst William Tanner in Expansion of Healthcare Coverage 2BellBrook Labs and Lankenau Institute Partner to Accelerate Drug Discovery using Orthogonal Pooled Screening 2Cytokinetics to Announce First Quarter Results on April 30, 2015 2Cytokinetics to Announce First Quarter Results on April 30, 2015 3Regis Technologies Joins American Association for Cancer Research Annual Meeting 2
... Biotherapeutics Holdings Inc. (Nasdaq: TLCR ) announced today ... Court Division, Wake County, North Carolina, rendered a verdict on ... favor of Plasma Centers of America, LLC, against its subsidiary, ... Talecris had a three-year Plasma Sale/Purchase Agreement with ...
... know right away that it,s hot. Ouch! But you can,t ... Rice University researchers say they have the next best ... molecule or flowing electrons by using Raman spectroscopy combined with ... of Douglas Natelson, a Rice professor of physics and astronomy, ...
... Dec. 13, 2010 BioTrends Research Group, Inc. ... oral disease-modifying agent (DMA) for the treatment of multiple sclerosis ... MS market. One month after the launch of Gilenya, trial ... year earlier, continues to be tempered due to the perception ...
Cached Biology Technology:Talecris Biotherapeutics Announces Jury Verdict in Contract Dispute 2Rice researchers take molecule's temperature 2Rice researchers take molecule's temperature 3With the Recent Launch of Novartis's Gilenya, Extavia is Pushed Into the Background of Multiple Sclerosis Treatment One Year After its Launch 2With the Recent Launch of Novartis's Gilenya, Extavia is Pushed Into the Background of Multiple Sclerosis Treatment One Year After its Launch 3
Includes a choice of any 3 EasySep mouse selection kits and EasySep magnet...
... 1.5mg of purified RNA samples., , This ... of aqueous RNA samples that have been ... phenol/chloroform, silica, oligo dT etc or other ... the necessary components for the stabilization of ...
Human SEAP ORF, provided in a pORF plasmid. pORF is an expression plasmid selectable with Ampicillin....
...
Biology Products: