Navigation Links
Could poor sleep contribute to symptoms of schizophrenia?
Date:11/14/2012

Neuroscientists studying the link between poor sleep and schizophrenia have found that irregular sleep patterns and desynchronised brain activity during sleep could trigger some of the disease's symptoms. The findings, published in the journal Neuron, suggest that these prolonged disturbances might be a cause and not just a consequence of the disorder's debilitating effects.

The possible link between poor sleep and schizophrenia prompted the research team, led by scientists from the University of Bristol, the Lilly Centre for Cognitive Neuroscience and funded by the Medical Research Council (MRC), to explore the impact of irregular sleep patterns on the brain by recording electrical brain activity in multiple brain regions during sleep.

For many people, sleep deprivation can affect mood, concentration and stress levels. In extreme cases, prolonged sleep deprivation can induce hallucinations, memory loss and confusion all of which are also symptoms associated with schizophrenia.

Dr Ullrich Bartsch, one of the study's researchers, said: "Sleep disturbances are well-documented in the disease, though often regarded as side effects and poorly understood in terms of their potential to actually trigger its symptoms."

Using a rat model of the disease, the team's recordings showed desynchronisation of the waves of activity which normally travel from the front to the back of the brain during deep sleep. In particular the information flow between the hippocampus involved in memory formation, and the frontal cortex involved in decision-making, appeared to be disrupted. The team's findings reported distinct irregular sleep patterns very similar to those observed in schizophrenia patients.

Dr Matt Jones, the lead researcher from the University's School of Physiology and Pharmacology, added: "Decoupling of brain regions involved in memory formation and decision-making during wakefulness are already implicated in schiz
'/>"/>

Contact: Caroline Clancy
caroline.clancy@bristol.ac.uk
44-011-792-88086
University of Bristol
Source:Eurekalert

Page: 1 2

Related biology news :

1. Heart-powered pacemaker could one day eliminate battery-replacement surgery
2. New test could help track down and prosecute terrorists
3. New antibiotic could make food safer and cows healthier
4. BPA could affect reproductive capabilities, cause infection of the uterus
5. Key to immune system disease could lie inside the cheek
6. New analysis of premature infants heartbeats, breathing could be cues for leaving NICU
7. Tiny electrical sensors could signal faster MRSA diagnosis
8. Corals could survive a more acidic ocean
9. Early warning system for seizures could cut false alarms
10. Rapid method of assembling new gene-editing tool could revolutionize genetic research
11. 800-year-old farmers could teach us how to protect the Amazon
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/4/2014)... CITY, Nov. 5, 2014 – University of Utah engineers ... to help jet fuel produce electricity without needing to ... used to power portable electronics, off-grid power and sensors. ... today in the American Chemical Society journal ACS ... through a chemical reaction between a fuel and an ...
(Date:11/4/2014)... CORAL GABLES, Fla. (November 4, 2014) — Think about ... and ask: How do neighboring cells know that they ... cell and how do these tissues find the correct ... (UM) are answering these crucial questions. , In a ... tissues use to communicate with their surrounding neighbors, at ...
(Date:11/4/2014)... A majority of Madagascar,s 101 species of lemurs are ... for the rainforests they call home. A new study ... can have on rainforest tree populations, which raises concerns ... the region,s rich biodiversity. , A large proportion of ... Lemurs in turn disperse the seeds of their ...
Breaking Biology News(10 mins):Jet-fueled electricity at room temperature 2The inside story: How the brain and skull stay together 2Gardeners of Madagascar rainforest at risk 2Gardeners of Madagascar rainforest at risk 3
... can discover recent dramatic developments at Kilauea Volcano, who is ... helps forecast and notify emergency managers of potential floods, which ... You can also find out how the USGS is helping ... gearing-up for baseball season, learn about the evolution and importance ...
... to support what mothers everywhere have long suspected: the ... an article titled Food Restriction Compromises Immune Memory in ... Numbers, Lynn Martin and coauthors find that reduced food ... their subjects. The findings, which will be published ...
... are not only smart, but they also wage a ... Previous studies have shown that plants can sense attacks ... not been known what happens between the pathogen attacks ... study revealed a very complex process that explains how ...
Cached Biology News:USGS April 2008 science picks 2USGS April 2008 science picks 3USGS April 2008 science picks 4USGS April 2008 science picks 5USGS April 2008 science picks 6USGS April 2008 science picks 7USGS April 2008 science picks 8Feed that cold! 2Researcher discovers pathway plants use to fight back against pathogens 2
(Date:11/26/2014)... HOUSTON and PHILADELPHIA , ... the most demanding and unforgiving environments. Human exploration of ... cognitive performance to ensure mission safety and success, and ... cognitive performance for mission success, little is known about ... aspects of cognition are primarily affected. Now, ...
(Date:11/26/2014)... The ETC (Emerging Technology Centers) http://www.etcbaltimore.com , ... that applications for AccelerateBaltimore™ (AB) 2015 program will ... a big idea?,” asked ETC’s President Deb Tillett. ... AccelerateBaltimore helps you and your big idea go ... Interested game changers with “big ideas” should ...
(Date:11/26/2014)... November 25, 2014 SonaCare Medical, ... Ultrasound (HIFU) devices, recently participated in the American ... Mass 360° .” Key opinion leaders in urology ... related to small renal masses while attendees had ... ablative technologies in hands-on labs. Attendees at the ...
(Date:11/26/2014)... 2014 The Pittcon marketing department is ... and exposition mobile app, Pittcon 2015 ... the App Store for iOS and Android devices and ... before, during and after the event. It acts as ... companies, technical sessions, Conferee Networking sessions and short courses. ...
Breaking Biology Technology:Penn Medicine Team Develops Cognitive Test Battery to Assess the Impact of Long Duration Spaceflights on Astronauts' Brain Function 2Penn Medicine Team Develops Cognitive Test Battery to Assess the Impact of Long Duration Spaceflights on Astronauts' Brain Function 3Penn Medicine Team Develops Cognitive Test Battery to Assess the Impact of Long Duration Spaceflights on Astronauts' Brain Function 4AccelerateBaltimore Applications to Close in 6 Days 2AccelerateBaltimore Applications to Close in 6 Days 3SonaCare Medical Supports American Urology Association’s Small Renal Mass 360° Summit 2SonaCare Medical Supports American Urology Association’s Small Renal Mass 360° Summit 3Pittcon Releases 2015 Mobile App 2
... March 11 Indevus,Pharmaceuticals, Inc. (Nasdaq: IDEV ) ... and Company 28th Annual Health Care Conference, on,Tuesday, March ... being held in,Boston, Massachusetts. The presentation will be web ... section of the Indevus website at, http://www.indevus.com ., ...
... Lett, CEO of The,BioAnalytics Group LLC and Ned ... Tucson Symposium on March 12-13, 2008. The,symposium, subtitled, ... Diagnostics," will be attended by hundreds of,scientists and ... Dr. Lett,s invited presentation will focus on ...
... France, March 11 Transgene,(Euronext Paris: FR0005175080) announces ... and outlook for 2008., "2007 was a ... the signing of a partnership agreement with Roche ... of diseases caused by the,HPV virus, and the ...
Cached Biology Technology:Indevus Pharmaceuticals to Present at Cowen and Company 28th Annual Health Care Conference 2Indevus Pharmaceuticals to Present at Cowen and Company 28th Annual Health Care Conference 3BioAnalytics Group CEO, Senior Scientist to Present at Tucson Symposium March 12-13 2Transgene in 2007: Partnership and Refinancing Position the Company for its Future Development 2Transgene in 2007: Partnership and Refinancing Position the Company for its Future Development 3Transgene in 2007: Partnership and Refinancing Position the Company for its Future Development 4Transgene in 2007: Partnership and Refinancing Position the Company for its Future Development 5Transgene in 2007: Partnership and Refinancing Position the Company for its Future Development 6Transgene in 2007: Partnership and Refinancing Position the Company for its Future Development 7Transgene in 2007: Partnership and Refinancing Position the Company for its Future Development 8Transgene in 2007: Partnership and Refinancing Position the Company for its Future Development 9Transgene in 2007: Partnership and Refinancing Position the Company for its Future Development 10Transgene in 2007: Partnership and Refinancing Position the Company for its Future Development 11Transgene in 2007: Partnership and Refinancing Position the Company for its Future Development 12
Request Info...
... 30 L samples, featuring 24-position turntable. Provides up to 30 minutes of walkaway time. ... analysis and record keeping. RS-232 port. ... ... ...
... mL - 25 mL pipets ,Angled acrylic pipet ... standard square or round pipet cans. Constructed of 6 ... 76 mm W x 76 mm H x 289 ... Overall dimensions: 89 mm W x 406 mm H ...
...
Biology Products: