Navigation Links
Could patients' own kidney cells cure kidney disease?
Date:7/27/2011

  • Patients' own kidney cells can be reprogrammed and used as therapy against kidney disease
  • Cells can easily be collected from the urine
  • 88,000 patients are waiting for a kidney transplant in the United States, and they wait for an average of 3 to 5 years

Washington, DC (July 27, 2011) Approximately 60 million people across the globe have chronic kidney disease, and many will need dialysis or a transplant. Breakthrough research published in the Journal of the American Society Nephrology (JASN) indicates that patients' own kidney cells can be gathered and reprogrammed. Reprogramming patients' kidney cells could mean that in the future, fewer patients with kidney disease would require complicated, expensive procedures that affect their quality of life.

In the first study, Sharon Ricardo, PhD (Monash University, in Clayton, Australia) and her colleagues took cells from an individual's kidney and coaxed them to become progenitor cells, allowing the immature cells to form any type in the kidney. Specifically, they inserted several key reprogramming genes into the renal cells that made them capable of forming other cells.

In a second study, Miguel Esteban, MD, PhD (Chinese Academy of Sciences, in Guangzhou, China) and his colleagues found that kidney cells collected from a patient's urine can also be reprogrammed in this way. Using cells from urine allows a technology easy to implement in a clinic setting. Even better, the urine cells could be frozen and later thawed before they were manipulated.

If researchers can expand the reprogrammed cellscalled induced pluripotent stem cells (iPSCs)and return them to the patient, these IPSCs may restore the health and vitality of the kidneys. In addition to providing a potentially curative therapy for patients, the breakthroughs might also help investigators to study the causes of kidney disease and to screen new drugs that could be used to treat them.

I
'/>"/>

Contact: Adrienne Lea
alea@asn-online.org
202-503-6560
American Society of Nephrology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Strong El Niño could bring increased sea levels, storm surges to US East Coast
2. Penn vet researchers show lymphoma drug shrinks dog tumors, could lead to human treatment
3. New understanding of biomarkers could lead to earlier diagnosis of fatal diseases
4. New material could offer hope to those with no voice
5. Acidifying oceans could hit California mussels, a key species
6. PSA test for men could get a second life for breast cancer in women
7. Smelly socks could be a key to preventing malaria deaths in the developing world
8. University of Kentucky-led research could be path to new energy sources
9. Microalgae could be Texas next big cash crop
10. A mothers salt intake could be key to prenatal kidney development
11. New laser technology could kill viruses and improve DVDs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/8/2015)... NEW YORK , July 8, 2015  BD ... announced BD & Guidepoint Mentor, a new ... to Guidepoint,s expert network services. BD ... technologies to improve healthcare delivery and outcomes and, with ... start-up entrepreneur will be able to directly engage with ...
(Date:7/8/2015)... The consumer products industry for innovative ... products such as wearables, smart wallets & other smart technology ... devices continues to rapidly grow.  Biometrics & Wearable Device Companies ... Google Inc. (NASDAQ: GOOG ), Apple Inc. (NASDAQ: ... (NASDAQ: GPRO ) and Baidu Inc. (NASDAQ: BIDU ...
(Date:7/7/2015)... July 7, 2015  Based on its recent ... Sullivan recognizes Credence ID, LLC with the 2015 ... of the Year Award. Credence ID has developed ... its mission of offering enrollment and identification solutions ... Credence ID was formed by experts from the ...
Breaking Biology News(10 mins):BD and Guidepoint Team to Connect Healthcare Start-up Companies With Business and Scientific Experts 2BD and Guidepoint Team to Connect Healthcare Start-up Companies With Business and Scientific Experts 3Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 2Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 3Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 4Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 5Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 6Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 2Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 3Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 4Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 5
... of Toronto and SickKids Research Institute announced today that they ... Dutch Elm Disease. The researchers believe this is the ... Ophiostoma ulmi have been mapped. The findings, published ... help scientists figure out how to prevent the fungus from ...
... was issued today by WCS President and CEO Cristian Samper: ... by an historic, broad group of nations from around the ... manta ray species for protection by the Convention on International ... This vote is a first, critical step in working to ...
... Since the 1960s, psychiatrists have been hunting for substances ... high levels to produce the symptoms associated with schizophrenia. ... might be related to the hallucinogens phencyclidine (PCP) or ... of psychotic symptoms in schizophrenia. This "auto-intoxication" hypothesis led ...
Cached Biology News:The mysterious GRIN3A and the cause of schizophrenia 2
(Date:7/31/2015)... HONG KONG , July 31, 2015 ... "Company"), China,s leading provider of ... and stem cell storage services, today announced that the ... with the U.S. Securities and Exchange Commission. The filed ... year ended March 31, 2015. The Form 20-F can ...
(Date:7/30/2015)... ... July 31, 2015 , ... Ralco is honored to announce ... Lyon County Fair to be held August 5-9 in Marshall. The Ralco Enrichment Center ... come from and how agriculture impacts their daily lives. This unique exhibit also features ...
(Date:7/30/2015)... 30, 2015   GenoSpace , a leading ... and analysis of genomic and other biomedical data, ... joined the company as Vice President of Sales ... "GenoSpace partners with its ... analyze and explore complex sets of genomic, phenotypic ...
(Date:7/30/2015)... ... July 30, 2015 , ... The 2015 Market Research Report on the ... of the global Propanol market with a focus on the Chinese situation. Major companies ... Chemicals, Oxea, ISU Chemical, Sanofi, Royal Dutch Shell, LG Chem and Zhejiang Xinhua Chemical. ...
Breaking Biology Technology:China Cord Blood Corporation Files Its Annual Report on Form 20-F 2Ralco Announces Primary Sponsorship of Ralco Enrichment Center at Lyon County Fair 2GenoSpace Introduces Matthew Fischer as Vice President of Sales and Marketing 2Global Propanol Market Technical Data and Manufacturing Analysis 2020 2Global Propanol Market Technical Data and Manufacturing Analysis 2020 3
... Biosciences, Inc. announced today that David J. Mazzo, Ph.D., ... the 27th Annual J.P. Morgan Healthcare Conference in San ... Pacific Time (2:30pm Eastern Time). Dr. Mazzo,s presentation ... in development, the REG1 System, its pipeline and enterprise-level ...
... Accumetrics, Inc. has appointed Andrew Chisholm to the position ... right mix of energy and expertise to Accumetrics. ... in terms of our market penetration," says Timothy I. ... the medical diagnostics industry and his relationships with distributors ...
... Company,s commitment to innovation in drug-eluting stent technologyNATICK, ... BSX ) today announced that it ... drug-eluting stent technology company located in Galway, Ireland. ... has developed a novel technology for coating drug-eluting ...
Cached Biology Technology:Andrew Chisholm Appointed Vice President, Sales and Corporate Accounts at Accumetrics 2Boston Scientific Acquires Labcoat Limited 2Boston Scientific Acquires Labcoat Limited 3Boston Scientific Acquires Labcoat Limited 4
Practical tool for easy, effective sealing of 0.2ml PCR tubes and plates using cap strips....
Caliper offers a wide array of standard LabChip products designed to be used in combination with our AMS 90 and LabChip 3000 microfluidic platforms....
... Time- and temperature-controlled microwave ... Rehydration and Antigen Retrieval of ... offers ease of use, high ... and high performance. When used ...
... discovery system miniaturizes, integrates and automates ... LabChip technology, the LabChip 3000 performs ... flow fashion. LabChip assays are separations-based, ... what is achievable in homogenous, well-based ...
Biology Products: