Navigation Links
Could patients' own kidney cells cure kidney disease?
Date:7/27/2011

  • Patients' own kidney cells can be reprogrammed and used as therapy against kidney disease
  • Cells can easily be collected from the urine
  • 88,000 patients are waiting for a kidney transplant in the United States, and they wait for an average of 3 to 5 years

Washington, DC (July 27, 2011) Approximately 60 million people across the globe have chronic kidney disease, and many will need dialysis or a transplant. Breakthrough research published in the Journal of the American Society Nephrology (JASN) indicates that patients' own kidney cells can be gathered and reprogrammed. Reprogramming patients' kidney cells could mean that in the future, fewer patients with kidney disease would require complicated, expensive procedures that affect their quality of life.

In the first study, Sharon Ricardo, PhD (Monash University, in Clayton, Australia) and her colleagues took cells from an individual's kidney and coaxed them to become progenitor cells, allowing the immature cells to form any type in the kidney. Specifically, they inserted several key reprogramming genes into the renal cells that made them capable of forming other cells.

In a second study, Miguel Esteban, MD, PhD (Chinese Academy of Sciences, in Guangzhou, China) and his colleagues found that kidney cells collected from a patient's urine can also be reprogrammed in this way. Using cells from urine allows a technology easy to implement in a clinic setting. Even better, the urine cells could be frozen and later thawed before they were manipulated.

If researchers can expand the reprogrammed cellscalled induced pluripotent stem cells (iPSCs)and return them to the patient, these IPSCs may restore the health and vitality of the kidneys. In addition to providing a potentially curative therapy for patients, the breakthroughs might also help investigators to study the causes of kidney disease and to screen new drugs that could be used to treat them.

I
'/>"/>

Contact: Adrienne Lea
alea@asn-online.org
202-503-6560
American Society of Nephrology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Strong El Niño could bring increased sea levels, storm surges to US East Coast
2. Penn vet researchers show lymphoma drug shrinks dog tumors, could lead to human treatment
3. New understanding of biomarkers could lead to earlier diagnosis of fatal diseases
4. New material could offer hope to those with no voice
5. Acidifying oceans could hit California mussels, a key species
6. PSA test for men could get a second life for breast cancer in women
7. Smelly socks could be a key to preventing malaria deaths in the developing world
8. University of Kentucky-led research could be path to new energy sources
9. Microalgae could be Texas next big cash crop
10. A mothers salt intake could be key to prenatal kidney development
11. New laser technology could kill viruses and improve DVDs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... 21, 2014 /PRNewswire-iReach/ -- LiveScan Service Provider  ... to a partnership with Gabriel Health Institute, one ... growing Certified Nursing Assistant preparatory schools. The ... exclusive member of Binary,s LiveScan service provider,s owner/operator ... improve its service capabilities by widening the ...
(Date:8/21/2014)... finding that has implications for life in other extreme ... solar system, LSU Associate Professor of Biological Sciences Brent ... Foundation, or NSF, this week published a paper confirming ... lies 800 meters (2600 feet) beneath the surface of ... Given that more than 400 subglacial lakes and numerous ...
(Date:8/21/2014)... to Wednesday, Oct. 18-22, 2014 , WHERE: ... Drive, San Diego, CA 92101 , WHAT: ... presentations of the latest research in human genetics. ... featuring high-scoring abstracts on rare genetic variants in ... and treatment for sun sensitivity (Saturday, Oct. 18, ...
Breaking Biology News(10 mins):LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 2LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 3800 meters beneath Antarctic ice sheet, subglacial lake holds viable microbial ecosystems 2800 meters beneath Antarctic ice sheet, subglacial lake holds viable microbial ecosystems 3800 meters beneath Antarctic ice sheet, subglacial lake holds viable microbial ecosystems 4American Society of Human Genetics 2014 Annual Meeting 2
... A potential new treatment for alcoholism called nalmefene ... alcohol dependent individuals, says a new study published this ... has been regarded as the primary treatment goal for ... approved only for relapse prevention. However, relapse rates remain ...
... unprecedented threat from climate change, overfishing, pollution, invasive ... researcher is helping coordinate national efforts to monitor ... for food, medicine, transportation and recreation, yet little ... 70 percent of the Earth,s surface are functioning ...
... bacteria that adhere to surfaces and build protective coatings ... pathogen Salmonella . One out of every six ... over a million illnesses caused by Salmonella bacteria, ... out what makes Salmonella resistant to antibacterial measures ...
Cached Biology News:A new treatment option for alcohol dependence: Reduced consumption rather than abstinence 2Scientists stress need for national marine biodiversity observation network 2Scientists stress need for national marine biodiversity observation network 3Biofilms help Salmonella survive hostile conditions, Virginia Tech researchers say 2
(Date:8/21/2014)... 21, 2014 OTC Markets Group ... a biotechnology company, on its approval to list ... on OTCQX®, the best marketplace for established U.S. ... Logo - http://photos.prnewswire.com/prnh/20110118/MM31963LOGO ... execution of its growth strategy and achievement of ...
(Date:8/21/2014)... Pursuit Solutions ( http://www.pursuit-solutions.com ), a ... for Life Sciences sales and marketing organizations, announced ... Commercial Sales Models” by Peter Robinson, co-founder and ... examines some innovative models used to improve sales ... the pharmaceutical market. Robinson grades the industry on ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 ... has been recognized as one of the nation’s ... 5000 magazine for the 2nd consecutive year. Inc. ... 33rd annual Inc. 500|5000, an exclusive ranking of ... the most comprehensive look at the most important ...
(Date:8/20/2014)... licensed to biotechnology firms has revealed early bottlenecks ... roadblocks, the researchers suggest that better communication of ... lead to faster commercialization down the road. , ... in university laboratories and licensed to biotechnology firms. ... have a high failure rate. But a new ...
Breaking Biology Technology:OTC Markets Group Congratulates Immune Pharmaceuticals on NASDAQ Listing 2Pursuit's Peter Robinson Publishes "Grading Pharma's Use of New Commercial Sales Models" 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3Early bottlenecks in developing biopharmaceutical products delay commercialization 2Early bottlenecks in developing biopharmaceutical products delay commercialization 3
... ... to holding a spring medical device package testing seminar in March of 2010 , ... Minneapolis, MN (PRWEB) February 2, 2010 ... testing , has confirmed that it will host a packaging seminar focused towards the medical ...
... , , , , , , ... Bioscience, a company,providing customized enzymes to the pharmaceutical, chemical, and other,industries, ... EUR 2,million from existing shareholders. , ... families to,its product portfolio and to accelerate the development of international,markets. ...
... ... 2 The biomedical industry is one of the most recession-resilient ... innovation, job growth and revenue that will help lead the state to ... Healthcare Institute (CHI) and PricewaterhouseCoopers LLP (PwC).  But, the report points ...
Cached Biology Technology:DDL to Host Spring Packaging Seminar 2EUCODIS Bioscience Receives EUR 2 Million Cash Injection to Enlarge Product Portfolio and Develop International Markets 2EUCODIS Bioscience Receives EUR 2 Million Cash Injection to Enlarge Product Portfolio and Develop International Markets 3Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers 2Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers 3Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers 4Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers 5Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers 6Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers 7Biomedical Industry Jobs Critical to California's Economic Recovery, Finds California Healthcare Institute and PricewaterhouseCoopers 8
...
... purification systems provide high speed purification of ... offer increased throughput and reproducible results. The ... mL and KingFisher 96, covering sample volumes ... consists of an instrument, specially designed plastics ...
Candida (IgA) -Ab EIA Sample Size: 5 l...
... Oxidized LDL (Competitive) EIA Principle: ... the monoclonal antibody 4E6. Oxidized LDL in the ... LDL bound to the microtiter well for the ... a washing st Sample Size: 25 ...
Biology Products: