Navigation Links
Could ovarian stimulation cause an increase in oocyte chromosome abnormalities?
Date:7/3/2011

Stockholm, Sweden: Ovarian stimulation undertaken by women of advanced maternal age (over 35 years) receiving fertility treatment may be disrupting the normal pattern of meiosis a critical process of chromosome duplication followed by two specialised cell divisions in the production of oocytes and sperm and leading to abnormalities of chromosome copy numbers (aneuploidy) that result in IVF failure, pregnancy loss or, more rarely, the birth of affected children with conditions such as Down's syndrome, which is caused by the inheritance of three copies of chromosome 21 (trisomy 21).

Researchers involved in ESHRE's polar body screening study (launched in 2009) will tell the annual conference of the European Society of Human Reproduction and Embryology today (Monday) that results from the study are leading to a new understanding about how such abnormalities are developing, and they believe that the ovarian stimulation a woman receives might be playing a part. Understanding the mechanisms involved could help older women who are trying to have a healthy baby with their own oocytes.

Professor Alan Handyside, Director of The London Bridge Fertility, Gynaecology and Genetics Centre, London, UK, and colleagues from eight countries undertook a proof of principle study of a novel method of screening polar bodies, small cells that are the by-product of oocyte development, using the new technology of microarray comparative genomic hybridisation (array CGH) in order to find whether this was a reliable method of analysing the chromosomal status of an oocyte. This is because many more chromosome copy number abnormalities arise in the oocyte than in sperm.

"In doing so, we obtained a lot of data at the individual chromosome and chromatid level," says Professor Joep Geraedts, co-ordinator of the ESHRE Task Force on preimplantation genetic screening (PGS). (A chromatid is one of the two identical copies of DNA making up a duplicated chromosome). "So w
'/>"/>

Contact: Mary Rice
mary.rice@riceconseil.eu
European Society of Human Reproduction and Embryology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Frog feet could solve a sticky problem
2. Climate change could turn oxygen-free seas from blessing to curse for zooplankton
3. Global warming could alter the US premium wine industry in 30 years, says Stanford study
4. Insight into plant behavior could aid quest for efficient biofuels
5. Branch offices: New family of gold-based nanoparticles could serve as biomedical testbed
6. Duke researchers learn how lung fibrosis begins and could be treated
7. Northern Eurasian snowpack could be a predictor of winter weather in US, team from UGA reports
8. Renaissance of 200-year old technology could ease 21st century sustainability challenges
9. UC Riverside neuroscientists discovery could bring relief to epilepsy sufferers
10. Device could improve harvest of stem cells from umbilical cord blood
11. Healing times for dental implants could be cut
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... whose turn it is to do the washing up, negotiating ... as many students returning to university for the new ... a house can be a tricky business. , And now ... that new technology to allow people to monitor their energy ... the tension. , The study by a team of technology ...
(Date:9/23/2014)... California , 23 de septiembre de ... lanzamiento del Sistema 1290 Infinity II LC, ... de Infinity en su portafolio de cromatografía ... científicos y directores de laboratorio que alcancen ... excepcional, facilidad de uso y capacidad de ...
(Date:9/22/2014)... 2014 A new American Cancer Society study suggests ... (SNAP), previously known as the food stamp program, ... eligible non-participants. The authors say the findings emphasize ... the dietary quality of SNAP participants. , The ... households with the resources to obtain a nutritionally ...
Breaking Biology News(10 mins):Smart meters could cause conflict for housemates, study shows 2Smart meters could cause conflict for housemates, study shows 3Agilent Technologies anuncia el lanzamiento del Sistema 1290 Infinity II LC 2Agilent Technologies anuncia el lanzamiento del Sistema 1290 Infinity II LC 3Federal food program puts food on the table, but dietary quality could be improved 2
... by the Smithsonian Institution has completed a new study ... a 3-foot-tall, 18,000-year-old hominin skeleton, discovered four years ago ... one of the most striking confirmations of the original ... one of the oldest human migrations to Asia. The ...
... 20, 2007) Fifteen students mentored by members of the ... receive the 2007ASPB Summer Undergraduate Research Fellowships (SURF). The ... to his or her research project for a 10-week ... to the mentor for lab supplies, a free student ...
... virus first struck New York City in 1999, news ... health officials alike, showing that even affluent, urban societies ... has been widely studied, there is still little known ... urban and rural areas. Assistant professor at the ...
Cached Biology News:New research sheds light on 'Hobbit' 2ASPB announces Summer Undergraduate Research Fellowship 2007 recipients 2ASPB announces Summer Undergraduate Research Fellowship 2007 recipients 3UGA Odum School of Ecology professor receives grant to study West Nile Virus in NYC 2
(Date:9/23/2014)... This is a professional and in-depth ... Resin industry in Global and China.The report provides ... applications and industry chain structure. Global market analysis ... a focus on history, developments, trends and competitive ... international and Chinese situation is also offered. , ...
(Date:9/23/2014)... (PRWEB) September 23, 2014 Erlab ... laboratory personnel since 1968 and Burdinola, supplier of laboratory ... a new filtered fume hood. , By ... fume hood, Burdinola will now offer an innovative solution ... wide range of chemicals, best-in-class detection technology, and communication ...
(Date:9/23/2014)... Proove Biosciences , the commercial and research leader ... association between specific genes and patients’ predisposition to anxiety ... Congress’ 27th Annual Scientific Program in Orlando, Florida. ... ‘Embracing Change.’ Mental health, and healthcare as a whole, ... presented by the Affordable Care Act to the growing ...
(Date:9/23/2014)... , Sept. 23, 2014 Research ... "Proteomics Markets for Research and IVD Applications ... report to their offering. ... proteomics applications, both in their research use and ... including the study of the structure and function ...
Breaking Biology Technology:Phenolic Resin Industry (International, China) Development Policy and Plan Now Available at ReportsnReports.com 2Erlab Partners with Burdinola to Deliver an Innovative Filtered Fume Hood 2Proove Biosciences Will Be Exhibiting New Genetic Research at the 27th Annual US Psych Congress Scientific Program 2Proove Biosciences Will Be Exhibiting New Genetic Research at the 27th Annual US Psych Congress Scientific Program 3Proteomics Markets for Research and IVD Applications (Mass Spectrometry, Chromatography, Microarrays, Electrophoresis, Immunoassays, Other Technologies) 2Proteomics Markets for Research and IVD Applications (Mass Spectrometry, Chromatography, Microarrays, Electrophoresis, Immunoassays, Other Technologies) 3Proteomics Markets for Research and IVD Applications (Mass Spectrometry, Chromatography, Microarrays, Electrophoresis, Immunoassays, Other Technologies) 4
... Md. and BEIJING, Jan. 10, 2012 The global ... as Aeras and the China National Biotec Group (CNBG) ... develop new tuberculosis (TB) vaccines. The agreement between the ... largest biotechnology corporation in China signals a commitment by ...
... A superlens would let you see a virus in a drop ... It might, says Durdu Guney, make ultra-high-resolution microscopes as commonplace as ... a superlens, also known as a perfect lens, though people are ... so-called diffraction limit, so even the best won,t usually let us ...
... . , Scientists at Universidad Carlos III ... have joined efforts to develop new materials for thermonuclear ... oxide dispersion-strengthened, reduced-activation steel for the reactor structure. , ... the current energy crisis. It is produced when ...
Cached Biology Technology:Aeras and CNBG Sign Agreement on Tuberculosis Vaccine R&D 2Aeras and CNBG Sign Agreement on Tuberculosis Vaccine R&D 3Almost perfect: A breakthrough in superlens development 2New material for thermonuclear fusion reactors 2New material for thermonuclear fusion reactors 3
Human LAIR2 Biotinylated Affinity Purified PAb...
... The mycobacteria in Complete Freund's ... the injection site which enhances the immuneresponse. ... is used for the initial injections; Incomplete ... boosts. Antigens (preferably in saline) are typically ...
2,4-Dinitrophenyl hapten is conjugated to Human Serum Albumin (HSA) protein through lysine....
Alexa Fluor 350/488/594 Filter Set (Semrock Brightline) *mounted* *Zeiss Axio AF...
Biology Products: