Navigation Links
Coping and copulation behavior may help calculate diabetes risk
Date:11/5/2008

November 6, 2008, Cambridge, UK Discussion of a man's background, attitude, and sexual history isn't just the fodder of Sex and The City episodes in the future, it could also be a way of evaluating his risk of diabetes.

Risk of developing type 2 diabetes and metabolic syndrome is determined by an individual's genetic background. Since this background has in turn been influenced by environment and behavior, it's important to consider these factors when assessing disease risk. While scientists have learned a lot about human disease through research in traditional laboratory mice, there are limits in studying genetic variation since controlled breeding and diet introduces artificially influences.

In order to study diabetes risk in a more naturally genetically diverse animal, Roxanne Oriel, Paul Vrana and colleagues studied glucose tolerance, a test often used to diagnose diabetes and metabolic syndrome, in a type of field mouse native to North America. As reported in their new study published in Disease Models & Mechanisms (DMM), dmm.biologists.org, they specifically chose two species of Peromyscus that are closely genetically related, but differ significantly in their behavioral traits and native environment.

During their tests, they discovered that merely handling the male mice and subjecting them to a placebo test where glucose was replaced with saline resulted in significant differences in blood sugar levels. Males of a calmer, more monogamous species had a higher level of stress hormones and a superior ability to regulate blood sugar, in comparison to males of a less calm, less monogamous species, or females of either species. In combination with studies with male mice bred to have only swapped "male" Y chromosomes, their study shows that a genetic variance linked to the Y chromosome is responsible for the species-specific responses of the males to stress.

Since previous studies of non-human primates by other research groups demonstrates a link between stress hormone levels and monogamy, the UC Irvine group propose that superior stress tolerance and blood sugar regulation is related to monogamy in these mice. Their work not only supports the study of mice with a more natural genetic background, but also points to the importance of considering gene-environment interactions, as well as behavior, when calculating risk of diabetes, metabolic syndrome, and other common diseases.


'/>"/>

Contact: Donna Perry
donna@biologists.com
44-012-234-33319
The Company of Biologists
Source:Eurekalert

Related biology news :

1. City birds better than rural species in coping with human disruption
2. New regulatory mechanism discovered for cell identify and behavior in forming organs
3. Premature children 4 times more likely to have behavioral disorders
4. Complex ocean behavior studied with artificial upwelling
5. Synthetic molecules emulate enzyme behavior for the first time
6. The 12th International Behavioral Ecology Congress held at Cornell University, Aug. 10-14
7. Its a unisex brain with specific signals that trigger male behavior
8. Amphibians respond behaviorally to impact of clear cutting
9. Research at Argonnes Advanced Photon Source reveals structure and behavior of collagen
10. Accelerometer backpacks aid study of gliding behavior in the flying lemur
11. Prison study to investigate link between diet and behavior
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/11/2017)... Jan. 11, 2017 Intoxalock, a leading ignition ... release of its patent-pending calibration device. With this new ... calibrations, securely upload data logs and process repairs at ... "Fighting drunk driving through the application of ... at large, but also for the customer who can ...
(Date:1/6/2017)... 2017  Delta ID Inc., a leader in consumer-grade ... automotive at CESĀ® 2017. Delta ID has collaborated with ... the use of iris scanning as a secure, reliable ... in a car, and as a way to elevate ... Delta ID and Gentex will demonstrate (booth #7326 ...
(Date:12/22/2016)... Calif. , Dec. 20, 2016  As part of ... 23andMe, the leading personal genetics company, recently released its latest ... . The book focuses on the topics of inheritance ... Generation Science Standards (NGSS) taught in elementary school classrooms in ... in a series by illustrator Ariana Killoran , whose ...
Breaking Biology News(10 mins):
(Date:1/19/2017)... ... January 19, 2017 , ... DaVita Clinical ... spectrum of drug and device development, and Prism Clinical Research , a ... today announced Verified Clinical Trials (VCT) has been selected by both ...
(Date:1/19/2017)... N.Y. , Jan. 18, 2017 Acupath ... services, announces the formation of an Executive Committee that ... and beyond. John Cucci , a ... promoted from Director of Business Development to Chief ... 2015, Mr. Cucci served in senior sales leadership roles ...
(Date:1/18/2017)... January 18, 2017 According to a new market research ... Cytology, Infectious Disease), & End User (Molecular Diagnostic Laboratories, Academic and Research Institutions) ... reach USD 739.9 Million by 2021 from USD 557.1 Million in 2016, growing ... ... MarketsandMarkets Logo ...
(Date:1/18/2017)... 2017   Parent Project Muscular Dystrophy (PPMD) , ... Duchenne muscular dystrophy (Duchenne) , today announced a $600,000 ... of Technology (NJIT) and Talem Technologies (Talem) as part ... to assist people living with Duchenne. PPMD is ... an embedded computer, software, a force sensor and a ...
Breaking Biology Technology: