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Controlling movements with light
Date:7/20/2011

le the same receptors in other cell types remained inactive. The RUB Department of General Zoology and Neurobiology has been instrumental in establishing this method worldwide.

Investigated receptor is crucial for movement control

The researchers found that activation of the G-protein-coupled receptor changed the activity pattern of the Purkinje cells. Herlitze's team had to expose the rhodopsin to light for several seconds to achieve these effects. A twenty to thirty percent reduction in cell activity was sufficient to induce visible motor deficits in the behaviour of the mice, such as impaired balance or coordination problems. "We were able to demonstrate for the first time that the modulation of a specific G-protein-coupled receptor in the Purkinje cells is of crucial importance for the control and coordination of movement", summed up Herlitze.


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Contact: Stefan Herlitze
stefan.herlitze@rub.de
49-234-322-4363
Ruhr-University Bochum
Source:Eurekalert

Page: 1 2

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