Navigation Links
Control gene for developmental timing discovered
Date:9/28/2011

University of Alberta researchers have identified a key regulator that controls the speed of development in the fruit fly. When the researchers blocked the function of this regulator, animals sped up their rate of development and reached maturity much faster than normal.

The U of A research team, led by molecular geneticist Kirst King-Jones, noticed a peculiar behaviour of the protein they were studying, DHR4: The protein acted as a sentinel to either allow or prohibit the production of steroid hormones by moving periodically between the cell nucleus to the cytoplasm.

In insects, these steroid hormone pulses control the progression of the fruit fly's development through the various stages of their life cycle. When the researchers blocked the function of DHR4 in the steroid hormone-producing cells, the maturation stage was reached 20 per cent faster than normal. In human terms this would mean that sexual maturity would be reached years earlier than normal.

In humans, steroid hormones play fundamental roles in the development of bodies and the onset of disease. King-Jones says the U of A research defines a novel mechanism by which steroid hormone pulses are regulated.

Fruit flies are commonly used in genetic research labs to study fundamental biological processes important for human health. The genes in many human diseases have a recognizable match in the genome of the fruit fly. For instance, the insect is used as a genetic model for diseases and neurodegenerative disorders such as Alzheimer's and Parkinson's disease. The fly is also a research tool for the study of obesity, diabetes and cancer.

Prior to the breakthrough by U of A researchers, little was known about the mechanism by which the timing of steroid hormone pulses, and thereby the onset of maturation, are controlled.


'/>"/>

Contact: Brian Murphy
brian.murphy@ualberta.ca
780-492-6041
University of Alberta
Source:Eurekalert

Page: 1

Related biology news :

1. Gene controlling flowering boosts energy production from sorghum
2. Fast-evolving genes control developmental differences in social insects
3. Temperature controls the genetic message
4. Researchers discover a switch that controls stem cell pluripotency
5. Shaping up: Controlling a stem cells form can determine its fate
6. Polonium poisoning case sheds light on infection control practices
7. UMass Amherst entomologists begin to control winter moth infestation in eastern Massachusetts
8. Sensory experience and rest control survival of newborn neurons in adults
9. Possible biological control discovered for pathogen devastating amphibians
10. Rats control appetite for poison
11. Biocontrol of sweetpotato weevils
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/11/2016)... http://www.apimages.com ) - --> http://www.apimages.com ) - ... Images ( http://www.apimages.com ) - Germany . ... new refugee identity cards. DERMALOG will be unveiling this device, and ... Hanover next week.   --> Germany ... the new refugee identity cards. DERMALOG will be unveiling this device, ...
(Date:3/9/2016)... -- This BCC Research report provides an overview of ... (RNA Seq) market for the years 2015, 2016 and ... data analysis, and services. Use this report ... such as RNA-Sequencing tools and reagents, RNA-Sequencing data analysis, ... segment and forecast their market growth, future trends and ...
(Date:3/3/2016)...  FlexTech, a SEMI Strategic Association Partner, awarded five ... Development, Leadership in Education, and, in a category new ... year of the FLEXI Awards and the winners ... past years . Judging was done on a ... criteria, by a panel of non-affiliated, independent, industry experts. ...
Breaking Biology News(10 mins):
(Date:5/2/2016)... , May 2, 2016 Q ... its technology partner Mannin Research Inc. will be attending ... which takes place from May 1-5, 2016 in ... be meeting with its vendors and research partners. The ... development goals and other collaborative opportunities for the MAN-01 ...
(Date:4/29/2016)... (PRWEB) , ... April 30, 2016 , ... The MIT ... textile design, the bioLogic team explored how bacterial properties can be applied to fabric ... using Natto bacteria, which move in response to humidity change. The team harvested Natto ...
(Date:4/29/2016)... ... 2016 , ... During a two day program for start-up ... CereScan’s CEO, John Kelley, joined other Denver business leaders in providing business basics ... Denver area business community, shared his top fundamental learnings in building an effective, ...
(Date:4/28/2016)... The report "Cryocooler Market by ... (Technical Support, Product Repairs & Refurbishment, Preventive Maintenance, and ... 2022", published by MarketsandMarkets, the global market is expected ... a CAGR of 7.29% between 2016 and 2022. ... Figures spread through 159 Pages and in-depth TOC on ...
Breaking Biology Technology: