Navigation Links
Consent forms for research: Have they improved in 25 years?
Date:5/28/2010

The consent forms that people sign before participating in research are widely considered difficult to understand and sometimes inaccurate. The lack of clarity was implicated in a high-profile legal settlement in April between Arizona State University and a Native American tribe, which claimed that blood samples that its members provided for genetic research were used for purposes not stated in the consent form. Efforts have been made to improve the forms, but how effective are they?

A study in IRB: Ethics & Human Research examined the changes over a quarter century in the accuracy and length of research consent forms used for 215 studies by one department in a major academic center. The review, by researchers at the University of Pennsylvania Law School and Columbia University, revealed two trends with potentially opposite effects on comprehensibility.

One trend is that the information in the consent forms became more accurate over time, as measured by discrepancies in the description of risks in the consent forms compared with the descriptions in the study protocols themselves. In the early consent forms evaluated in the study, which dated back to 1978, more than 54 percent had such discrepancies, mainly with the consent forms understating the actual risk. But by 2002, there were no discrepancies.

On the other hand, the consent forms became much longer, growing from an average of a paragraph or two to more than four and a half pages. The increased length could interfere with comprehension: the authors cite data showing that consent forms that are longer than four pages "are unlikely to be read, perhaps in part because of the time involved."

"Our findings highlight the inherent paradox in attempting to use consent forms to convey ever-more-complete information to potential research subjects," the authors write. "Greater information is associated with increased length of consent forms, and studies have shown an inv
'/>"/>

Contact: Michael Turton
turtonm@thehastingscenter.org
845-424-4040 x242
The Hastings Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Biologists find unusual plant gene: abstinence by mutual consent
2. UNC nanotech spin-off forms new venture with Siemens
3. Emergence of recombinant forms of HIV: dynamics and scaling
4. Simple screening questionnaire for kidney disease outperforms current clinical practice guidelines
5. Hope among patients with ALS may take a variety of forms
6. New vaccine may give long-term defense against deadly bird flu and its variant forms
7. Federal polar bear research critically flawed, says study in INFORMS journal
8. Lab study shows methadone breaks resistance in untreatable forms of leukemia
9. As Andean glacier retreats, tiny life forms swiftly move in, CU-Boulder study shows
10. Syracuse University researchers discover new way to attack some forms of leukemia
11. IODP to operate 3 drilling platforms in 2009
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... in smog-producing toxins in past decade, GTA still ... shows that while the Greater Toronto Area (GTA) ... contribute to smog, the city continues to violate ... which can cause or aggravate health problems such ... by a set of complex photochemical reactions involving ...
(Date:8/21/2014)... in near darkness use a previously unknown process for ... team led by a Penn State University scientist has ... aimed at improving plant growth, harvesting energy from the ... on Lake Erie and other lakes worldwide. A paper ... Science Express edition of the journal Science ...
(Date:8/21/2014)... Fla. , Aug. 21, 2014 /PRNewswire-iReach/ ... that it has agreed to a partnership ... Orlando,s fastest growing Certified Nursing ... Gabriel Health Institute  an exclusive member of ... result, Binary Biometrics will improve its service ...
Breaking Biology News(10 mins):Despite a significant reduction in smog-producing toxins, the Greater Toronto Area still violates Canada's standards for ozone air pollution 2Hot-spring bacteria reveal ability to use far-red light for photosynthesis 2Hot-spring bacteria reveal ability to use far-red light for photosynthesis 3LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 2LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 3
... the world’s largest and least studied freshwater turtles ... hopes that the threatened species can be saved ... World Wildlife Fund (WWF), the Cambodian Fisheries Administration, ... and released an 11-kilogram (24.2-pound) female Cantor’s giant ...
... have constructed the first global family tree of metabolic ... the evolutionary history of metabolism. , The study appears ... of the National Academy of Sciences. , Their ... in the past decade to plot the evolution of ...
... a mechanistic diagram describing the development of the Nematode ... been able to tease out what laboratory experiments have ... signaling pathways takes place in order to determine the ... is described in a paper appearing May 18, 2007 ...
Cached Biology News:Rare soft-shell turtle, nesting ground found in Cambodia 2Rare soft-shell turtle, nesting ground found in Cambodia 3Study of protein folds offers insight into metabolic evolution 2Study of protein folds offers insight into metabolic evolution 3Executable biology -- Computer science sheds light on animal development 2
(Date:8/21/2014)... for Molecular Medicine Finland (FIMM), University of Helsinki, ... "man and machine" decision support system for diagnosing ... in PLOS One scientific journal today, ... vision algorithms similar to those used in facial ... diagnostically most relevant areas. Tablet computers can be ...
(Date:8/21/2014)... August 21, 2014 ... has announced the addition of the  "Global ... their offering.       (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ... therapy, is a means of replacing hormones ... the body. This type of therapy is ...
(Date:8/21/2014)... New Rochelle, N.Y. (PRWEB) August 21, 2014 ... it is the first private college in the Mid-Hudson ... The College will now begin accepting applications from qualified ... , “We are very pleased to have been ... to support Governor Cuomo’s transformative initiative to stimulate economic ...
(Date:8/21/2014)... , Aug. 21, 2014 ... Immune Pharmaceuticals Inc., a biotechnology company, on its ... Immune previously traded on OTCQX®, the best marketplace ... OTC Markets Group. Logo - http://photos.prnewswire.com/prnh/20110118/MM31963LOGO ... on the successful execution of its growth strategy ...
Breaking Biology Technology:A novel 'man and machine' decision support system makes malaria diagnostics more effective 2Global Hormone Replacement Therapy Market 2014-2018: Key Vendors are Actavis, Bayer, Merck & Co, Novartis and Novo Nordisk 2The College of New Rochelle Becomes First Private College in Mid-Hudson Region to Earn START-UP NY Designation 2The College of New Rochelle Becomes First Private College in Mid-Hudson Region to Earn START-UP NY Designation 3OTC Markets Group Congratulates Immune Pharmaceuticals on NASDAQ Listing 2
... ,, NEW YORK , ... (SPOM),a leading developer of biosensor and microprocessor technologies for ... a unique bracelet,to measure the overall daily activity level ... are deemed to be overweight or obese. The bracelet,designed ...
... NUREMBERG , Germany , ... Imaging BV have joined forces to make the CAAS ... capability is the result of Ziehm Imaging,s strategic partnership ... ), a leading,developer of quantitative analysis software for cardiology ...
... ... effectively use this invaluable resource., , ... Seattle, WA (PRWEB) May 25, 2010 -- OpenHelix today ... is an integrated resource designed to provide access to current genetic testing and ...
Cached Biology Technology:SPO Medical Announces Innovative Wellness Bracelet 2SPO Medical Announces Innovative Wellness Bracelet 3SPO Medical Announces Innovative Wellness Bracelet 4SPO Medical Announces Innovative Wellness Bracelet 5Ziehm Imaging and Pie Medical Imaging Announce Cooperation 2Ziehm Imaging and Pie Medical Imaging Announce Cooperation 3Ziehm Imaging and Pie Medical Imaging Announce Cooperation 4Updated Online Tutorial for GeneTests 2
... , Maintenance 112 days/each , ... Immunizations/Boost injections x5 /each , ... , Production bleed (25 ml blood =12 ml ... ml blood (~50 ml serum) x1 each , ...
FluoSpheres® biotin-labeled microspheres, 1.0 µm, yellow-green fluorescent (505/515) *1% solids*...
chk 1 kinase...
muscle actin (HUC1-1)...
Biology Products: