Navigation Links
Conquest of land began in shark genome
Date:8/14/2007

adapt to swamps and terrestrial living, creating a distinct burst of development and more versatile appendages.

Using molecular markers to study the formation of skeletal cartilage in embryos of the spotted catshark, UF scientists isolated and tracked the activity of Hox genes, a group of genes that control how and where body parts develop in all animals, including people.

They discovered a phase of gene expression in sharks that was thought until recently to occur only when digits began to form in limbed animals.

Why, then, dont sharks have fingers?

Renata Freitas and GuangJun Zhang, co-authors of the paper and graduate students in the zoology department of the College of Liberal Arts and Sciences, speculate that sharks and many other types of fish do not form more dramatic appendages during this late phase of Hox gene expression because it occurs briefly and only in a narrow band of cells, compared with the more extended time frame and larger anatomical area needed to prefigure the hand and foot in limbed animals.

We know when this particular Hox gene is mutated in humans, it results in malformations of fingers and toes, Cohn said. Until now it was thought these mutations were affecting a relatively recent innovation in the genetic process of limb development. Our results show that this phase of Hox expression is much more ancient and suggest that if the origin of digits involved a prolonged activity of Hox genes, a truncated period could result in defective digits.

In a parallel study, researchers at the University of Chicago found this second phase of gene expression in paddlefish, a primitive living descendant of early fish with the first bony skeletons.

Finding the second phase in sharks, which have skeletons consisting not of bone but of cartilage, means the genetic processes necessary to muster fingers and toes existed more than 500 million years ago in the common ancestor of fish with cartila
'/>"/>

Contact: John Pastor
jdpastor@ufl.edu
352-273-5815
University of Florida
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Great White shark evolution debate involves WSU Lake Campus geology professor
2. Shark attack worries? Driving to the beach is more deadly
3. Plankton can run, but cant hide from basking sharks
4. Shark skin saves naval industry money
5. Oceans are 70 percent shark free
6. World shark attacks dipped in 2005, part of long-term trend
7. UF scientists trace origin of sharks electric sense
8. Ongoing collapse of coral reef shark populations
9. Triple threat: World fin trade may harvest up to 73 million sharks per year
10. Overfishing large sharks impacts entire marine ecosystem, shrinks shellfish supply
11. New research shows sharks use their noses and bodies to locate smells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... Conn. , Sept. 19, 2014 Nxt-ID, Inc. (Nasdaq: ... biometric authentication company focused on the growing m-commerce market, updates the ... world champion in the lightweight and light middleweight weight classes, ... Yesterday it was announced that Game of Thrones actor ... Married with Children star Katey Sagal have ...
(Date:9/18/2014)... circuit located deep in the primitive brainstem has revealed ... at Harvard School of Medicine and the University at ... only the second "sleep node" identified in the mammalian ... sufficient to produce deep sleep. , Published online in ... that fully half of all of the brain,s sleep-promoting ...
(Date:9/18/2014)... A team of researchers from McGill University and ... form of polyethylene ,microbeads, Canadian Journal of ... likely originate from cosmetics, household cleansers, or industrial ... abrasives. Owing to their small size and buoyancy, ... Microplastics are a global contaminant in the ...
Breaking Biology News(10 mins):NXT-ID's Vinny Paz Celebrity Ad Wocket Update: Katey Sagal and Ciaran Hinds Attached to His Upcoming Movie 2NXT-ID's Vinny Paz Celebrity Ad Wocket Update: Katey Sagal and Ciaran Hinds Attached to His Upcoming Movie 3No sedative necessary: Scientists discover new 'sleep node' in the brain 2Microplastic pollution discovered in St. Lawrence River sediments 2
... Institute,s Bocas del Toro Research Station and Galeta ... temperature rise and a major coral bleaching event ... Oceanic and Atmospheric Administration, NOAA, issued an advisory ... the wider Caribbean region, there had been no ...
... At a press conference held in Brussels today, the ... European Parliament Osteoporosis Interest Group called on health care professionals ... prevent spinal fractures. The call to action was made at ... spine, leading up to World Osteoporosis Day on October 20, ...
... plants with red flowers or flowers with stripes along the ... Antirrhinum majus , at the John Innes Centre in the ... well as the plants in our gardens. The John Innes ... that can benefit agriculture and the environment. "Stripes following ...
Cached Biology News:Smithsonian reports regional sea temperature rise and coral bleaching event in Western Caribbean 2IOF campaign puts spotlight on vastly under-diagnosed and under-treated spinal fractures 2Landing lights for bumblebees 2
(Date:9/22/2014)... -- Spherix Incorporated (SPEX) -- an intellectual property development company committed ... that the United States Patent & Trademark Office (USPTO) issued ... September that is part of a standard essential family of ... , Application number: US 13/728,867 , Publication date: ... The listed inventors of the new patent, ...
(Date:9/20/2014)... HealthTronics, Inc. , a leading ... and services, has signed a distribution agreement through ... for its high precision laser technology. ... mobile, surgical technology—offering more choices for healthcare providers ... will make available Clinicon’s FDA-cleared SureLase™ CO2 Laser ...
(Date:9/19/2014)... than electricity, to move data would consume much ... growing concern as chips, transistor counts rise. , ... light emitters, modulators, and detectors emitters ... source for optical chips is molybdenum disulfide (MoS2), ... a single, atom-thick layer. Other experimental on-chip light ...
(Date:9/19/2014)... , Sept. 19, 2014 Pfenex Inc. (NYSE ... development of high-value and difficult to manufacture proteins including ... at the 21 st Annual NewsMakers in the ... . Bertrand Liang , chief executive officer of ... programs and business strategy on Friday, September 26, 2014 ...
Breaking Biology Technology:Spherix Notified by United States Patent & Trademark Office of New Standard Essential Patent Issued to Spherix 2Spherix Notified by United States Patent & Trademark Office of New Standard Essential Patent Issued to Spherix 3HealthTronics Announces Distribution Agreement with Clinicon-Laser Surgical Device Expands Minimally Invasive, Mobile Technology Portfolio 2HealthTronics Announces Distribution Agreement with Clinicon-Laser Surgical Device Expands Minimally Invasive, Mobile Technology Portfolio 3Toward optical chips 2Toward optical chips 3Pfenex to Present at Upcoming Industry Conference on September 26 2
... ... with the transaction advisory support for the successful sale of Helsinn Chemicals Ireland Ltd ... transaction can be found at http://www.prnewswire.co.uk/cgi/news/release?id=259822 . , ... Oxford, UK (PRWEB) June 24, 2009 -- PharmaVentures ...
... CEL-SCI CORPORATION (NYSE AMEX: CVM ) announced ... covering its L.E.A.P.S.(TM) immune therapy drugs (vaccines) for the prevention/treatment ... or variants of these viruses. Some experts believe that ... have evolved and/or combined with other viruses to create a ...
... (NYSE AMEX: CVM ) , a ... entered into a definitive agreement with one institutional investor to ... of the Company,s common shares and 0.67 warrants to purchase ... $5.0 million, before deducting placement agent fees and estimated offering ...
Cached Biology Technology:PharmaVentures Assists Helsinn in the Successful Sale of Helsinn Chemicals Ireland to the Medinco C.F.M. Group 2CEL-SCI Files Patent Application to Support Company's Treatment for More Virulent Strain of H1N1 Swine and Other Influenza Viruses 2CEL-SCI Files Patent Application to Support Company's Treatment for More Virulent Strain of H1N1 Swine and Other Influenza Viruses 3CEL-SCI Signs Definitive Agreement to Raise $5 Million in Registered Direct Offering 2CEL-SCI Signs Definitive Agreement to Raise $5 Million in Registered Direct Offering 3
... Drosophila S2 cells are used for heterologous ... System (DES). The S2 cell line was ... (20-24 hours old) Drosophila melanogaster embryos ... at room temperature without CO2 and is easily ...
Mouse monoclonal antibody to RAD51L3 - RAD51-like 3 (S. cerevisiae)...
... new product number, created to easily match ... yet, please order under the old Sigma-Aldrich ... assistance. Feature: tissue-culture treated yes ... cm 2 D H 60 ...
... Nop1p/Fibrillarin was originally identified ... yeast, Saccharomyces cerevisiae (accession P15646). The ... viability and is localized in the ... is fibrillarin (accession P22087) a component ...
Biology Products: