Navigation Links
Conquest of land began in shark genome
Date:8/14/2007

GAINESVILLE, Fla. When the first four-legged animals sprouted fingers and toes, they took an ancient genetic recipe and simply extended the cooking time, say University of Florida scientists writing in Wednesdays issue of the journal PLoS ONE.

Even sharks which have existed for more than half a billion years have the recipe for fingers in their genetic cookbook not to eat them, but to grow them.

While studying the mechanisms of development in shark embryos, UF scientists identified a spurt of genetic activity that is required for digit development in limbed animals.

Previous work suggested that the transition from fins to limbs involved the addition of a late phase of gene activity during embryonic development, something thought to be absent during the development of fish fins.

The finding shows what was thought to be a relatively recent evolutionary innovation existed eons earlier than previously believed, shedding light on how life on Earth developed and potentially providing insight for scientists seeking ways to cure human birth defects, which affect about 150,000 infants annually in the United States.

Weve uncovered a surprising degree of genetic complexity in place at an early point in the evolution of appendages, said developmental biologist Martin Cohn, Ph.D., an associate professor with the UF departments of zoology and anatomy and cell biology and a member of the UF Genetics Institute. Genetic processes were not simple in early aquatic vertebrates only to become more complex as the animals adapted to terrestrial living. They were complex from the outset. Some major evolutionary innovations, like digits at the end of limbs, may have been achieved by prolonging the activity of a genetic program that existed in a common ancestor of sharks and bony fishes.

Researchers say the same genes that produced ancient fins likely enlarged their role about 365 million years ago in amphibians struggling to
'/>"/>

Contact: John Pastor
jdpastor@ufl.edu
352-273-5815
University of Florida
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Great White shark evolution debate involves WSU Lake Campus geology professor
2. Shark attack worries? Driving to the beach is more deadly
3. Plankton can run, but cant hide from basking sharks
4. Shark skin saves naval industry money
5. Oceans are 70 percent shark free
6. World shark attacks dipped in 2005, part of long-term trend
7. UF scientists trace origin of sharks electric sense
8. Ongoing collapse of coral reef shark populations
9. Triple threat: World fin trade may harvest up to 73 million sharks per year
10. Overfishing large sharks impacts entire marine ecosystem, shrinks shellfish supply
11. New research shows sharks use their noses and bodies to locate smells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... 2014  23andMe, Inc., the leading personal genetics company, ... fine-scale differences in genetic ancestry of individuals from across ... Since immigrants first arrived more than four hundred years ... served as a meeting place for peoples from different ... ongoing mixing of peoples with African, European, and American ...
(Date:12/17/2014)... 15, 2014 Research and Markets ... the "Samsung Galaxy S5 - Home Button ... their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... sensing technology than the iPhone 5S, Samsung introduces ... its product. The Galaxy S5 home ...
(Date:12/17/2014)... NEW YORK , Dec. 15, 2014 /PRNewswire-USNewswire/ ... a Good Clinical Practices (GCP) audit to confirm ... Administration (FDA) regulations. This accomplishment enables HITLAB to ... trials utilizing the highest principles for patient safety ... to improve global healthcare access, quality, and delivery ...
Breaking Biology News(10 mins):23andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2
... Medicine have enhanced our understanding of the mechanism by ... food is converted into the energy required by cells. ... how organisms synthesize their major form of chemical energy. ... of PLoS Biology . Cells use the ...
... Mont. -- Researchers at Montana State University have ... for treating antibiotic resistant infections, fungal infections and viral ... to study such compounds. The technologies are ... The first technology involves an existing clinical drug ...
... YORK and LEON, GUANAJUATO MEXICO, Aug. 18 Global ... and identity management market, announced today that it will ... Leon, Guanajuato, Mexico. Portoss, a Leon-based company, specializes in ... latest partnership between Portoss and the City of Leon ...
Cached Biology News:Mount Sinai researchers discover new mechanism behind cellular energy conversion 2Montana State University offers 6 new biomedical technologies for licensing 2Montana State University offers 6 new biomedical technologies for licensing 3Montana State University offers 6 new biomedical technologies for licensing 4Global Rainmakers Delivers World Class Iris Capability for Portoss 2Global Rainmakers Delivers World Class Iris Capability for Portoss 3
(Date:12/24/2014)... December 23, 2014 Earlier this year ... L. Sherley, director of the Adult Stem Cell Technology ... often overlooked and under appreciated unique property of adult ... Distributed Stem Cells: Misunderstood in the Past, Important for ... congress participants. He gave the address at the ...
(Date:12/24/2014)... Tenn. (PRWEB) December 23, 2014 Nashville ... was elected treasurer for the American Society for ... advancing knowledge and research in reproductive medicine. In ... a seat on the executive board and will have ... , Dr. Hill has actively supported ASRM since 1984 ...
(Date:12/24/2014)... , December 23, 2014 ... Algeria , out today and available for free download ... actors driving change and growth in the sector today. ... scored notable successes has been in developing a homegrown pharmaceutical ... percent local production still remains some way off. A cursory ...
(Date:12/22/2014)... Dec. 22, 2014   Synthetic Biologics, ... of pathogen-specific therapies for serious infections and ... microbiome, today announced positive topline safety and ... trial of SYN-004, the Company,s investigational oral ... Clostridium difficile (C. difficile) infection, antibiotic-associated ...
Breaking Biology Technology:Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 2Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 4Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 5
... Colo., Oct. 9 Replidyne, Inc.,(Nasdaq: RDYN ) ... and,webcast on Tuesday, October 30, 2007 at 4:45 P.M. ... in the conference call by,dialing 800-435-1261 (domestic) or 617-614-4076 ... the conference call will be available approximately one,hour after ...
... of Clinical Programs, PALO ALTO, Calif., Oct. ... a late-stage biotechnology company that,develops central nervous system ... be a presenting company at the 4th,Annual BIO ... at the,Palace Hotel of San Francisco. The company,s ...
... Oct. 8 Inverness Medical,Innovations (Amex: IMA ) ... Agreement with Panbio Ltd, an Australian company traded on,the ... will acquire all of the issued shares in Panbio ... values the issued share capital of,Panbio at approximately AUD ...
Cached Biology Technology:Replidyne to Announce Third Quarter 2007 Earnings 2Avicena to Present at 4th Annual BIO InvestorForum Conference 2Inverness Medical Innovations Agrees to Acquire Panbio Ltd. 2
Collected from sexually matured, mixed breed, mixed sex guinea pigs....
Antibody specific for phosphorylattion of histone H3 that occurs during mitosis. Rabbit polyclonal serum. Antigen: Synthetic peptides derived from histone H3, phosphorylated at serines 10 or 28...
DTT, 25g...
...
Biology Products: