Navigation Links
Connection between light at night and cancer revealed in additional study
Date:9/2/2010

A new study from the Center for Interdisciplinary Chronobiological Research at the University of Haifa has found an additional link between Light At Night (LAN) and cancer. This research joins a series of earlier studies carried out at the University of Haifa that also established the correlation. "High power light bulbs contribute more to 'environmental light pollution', which the study has shown is a carcinogenic pollution," notes Prof. Abraham Haim, who headed the study.

Earlier studies in which Prof. Haim has participated at the University of Haifa, have shown that people living in areas that have more night-time illumination are more susceptible to prostate cancer in men and breast cancer in women. The researchers' hypothesis was that LAN harms production of melatonin, a hormone that is released from the pineal gland during the dark part of the 24h cycle and which is linked to the body's cyclical night-day activity and seasonality. When this hormone is suppressed, the occurrence of cancer rises.

The current study, in which Dr. Fuad Fares and Adina Yokler, Orna Harel and Hagit Schwimmer also participated, set out to establish or refute this hypothesis. In order to do so, four groups of lab mice injected with cancerous cells were examined: one group was exposed to "long days" of 16 hours of light and 8 hours of darkness, simulating exposure to artificial light beyond the natural number of light hours in a day; a second group was exposed to the same "long days" but were treated with melatonin; a third group was exposed to "short days" of 8 light hours and 16 dark hours; and a fourth group was exposed to the same "short days" but during the dark hours was exposed to a half-hour interval of light.

The results show once again the clear link between LAN and cancer: the cancerous growths in mice exposed to "short days" were smallest (0.85 cubic cm. average), while those mice exposed to the interval of LAN during dark hours had larger growths (1.84 cubic cm. average) and those exposed to "long days" even larger growths (5.92 cubic cm. average).

The study also discovered that suppression of melatonin definitely influences development of the tumor. The size of tumor in mice exposed to "long days" but treated with melatonin was only 0.62 cubic cm. on average, which is not much different from the size of the growth in mice exposed to "short days". The study also found that the death rate in mice treated with melatonin was significantly lower than in those not treated.

The researchers say that their study results show that suppression of melatonin due to exposure to LAN is linked to the worrying rise in the number of cancer patients over the past few years. However, it is not yet clear what mechanism causes this.

"Exposure to LAN disrupts our biological clock and affects the cyclical rhythm that has developed over hundreds of millions of evolutionary years that were devoid of LAN. Light pollution as an environmental problem is gaining awareness around the world, and the World Health Organization's International Agency for Research on Cancer (IARC) has already classified working the night shift as a higher grade of cancer risk," the researchers noted.


'/>"/>

Contact: Rachel Feldman
rfeldman@univ.haifa.ac.il
972-482-88722
University of Haifa
Source:Eurekalert

Related biology news :

1. Connection between light at night (LAN) and cancer revealed in additional study
2. Brain connections break down as we age
3. Calcium connections: Basic pathway for maintaining cells fuel stores
4. Searching for causes of neural disconnection in schizophrenia
5. Connection elucidated between obesity, salt sensitivity and high blood pressure
6. Brain connections for stress -- lessons from the worm
7. Impaired brain connections traced to schizophrenia mutation
8. Lifelong memories linked to stable nerve connections
9. The food-energy cellular connection revealed
10. Ben-Gurion U. researchers reveal connection between cancer and human evolution
11. MU study finds connection between evolution, classroom learning
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/2/2016)... Checkpoint Inhibitors for Cancer – Explore ... you interested in the future of cancer drugs? ... Visiongain,s report gives those predictions to 2026 at ... Avoid falling behind in data or losing ... those emerging cancer therapies can achieve. There you ...
(Date:2/2/2016)... 2016   Parabon NanoLabs (Parabon) announced ... Research Office and the Defense Forensics and Biometrics ... the company,s Snapshot Kinship Inference software ... generally, defense-related DNA forensics.  Although Snapshot is best ... and ancestry from DNA evidence), it also has ...
(Date:2/1/2016)... Canada , February 1, 2016 ... technological advancements to drive global touchfree intuitive gesture control ... --> Rising sales of consumer electronics coupled ... gesture control market size through ... consumer electronics coupled with new technological advancements to drive ...
Breaking Biology News(10 mins):
(Date:2/5/2016)... February 5, 2016 Amarantus BioScience ... company focused on developing products for Regenerative Medicine, Neurology ... Pediatric Disease Designation (RPDD) from the US Food and ... MANF. MANF was previously granted orphan drug designation (ODD) ... Amarantus BioScience Holdings, Inc. (OTCQB: AMBS), ...
(Date:2/4/2016)... ... February 04, 2016 , ... ... training, today announced an interactive FDA compliance training course, Writing ... Affairs Professional Society) accredited interactive course on Morf Playbook—now conveniently available on smartphones ...
(Date:2/4/2016)... RICHMOND, Calif. , Feb. 4, 2016  Sangamo ... therapeutic genome editing, announced today that Edward Lanphier ... an update on the progress of Sangamo,s ZFP Therapeutic ... company,s business strategy at 2:40 pm ET on Thursday, ... Annual Global Healthcare Conference. The conference is being ...
(Date:2/4/2016)... ... February 04, 2016 , ... ... Bloomsburg University’s Digital Forensics Club, takes place February 5-6 at the University’s ... 20+ speakers and activities such as workshops and competitions for ample networking, ...
Breaking Biology Technology: