Navigation Links
Connection between light at night and cancer revealed in additional study
Date:9/2/2010

A new study from the Center for Interdisciplinary Chronobiological Research at the University of Haifa has found an additional link between Light At Night (LAN) and cancer. This research joins a series of earlier studies carried out at the University of Haifa that also established the correlation. "High power light bulbs contribute more to 'environmental light pollution', which the study has shown is a carcinogenic pollution," notes Prof. Abraham Haim, who headed the study.

Earlier studies in which Prof. Haim has participated at the University of Haifa, have shown that people living in areas that have more night-time illumination are more susceptible to prostate cancer in men and breast cancer in women. The researchers' hypothesis was that LAN harms production of melatonin, a hormone that is released from the pineal gland during the dark part of the 24h cycle and which is linked to the body's cyclical night-day activity and seasonality. When this hormone is suppressed, the occurrence of cancer rises.

The current study, in which Dr. Fuad Fares and Adina Yokler, Orna Harel and Hagit Schwimmer also participated, set out to establish or refute this hypothesis. In order to do so, four groups of lab mice injected with cancerous cells were examined: one group was exposed to "long days" of 16 hours of light and 8 hours of darkness, simulating exposure to artificial light beyond the natural number of light hours in a day; a second group was exposed to the same "long days" but were treated with melatonin; a third group was exposed to "short days" of 8 light hours and 16 dark hours; and a fourth group was exposed to the same "short days" but during the dark hours was exposed to a half-hour interval of light.

The results show once again the clear link between LAN and cancer: the cancerous growths in mice exposed to "short days" were smallest (0.85 cubic cm. average), while those mice exposed to the interval of LAN during dark hours had larger growths (1.84 cubic cm. average) and those exposed to "long days" even larger growths (5.92 cubic cm. average).

The study also discovered that suppression of melatonin definitely influences development of the tumor. The size of tumor in mice exposed to "long days" but treated with melatonin was only 0.62 cubic cm. on average, which is not much different from the size of the growth in mice exposed to "short days". The study also found that the death rate in mice treated with melatonin was significantly lower than in those not treated.

The researchers say that their study results show that suppression of melatonin due to exposure to LAN is linked to the worrying rise in the number of cancer patients over the past few years. However, it is not yet clear what mechanism causes this.

"Exposure to LAN disrupts our biological clock and affects the cyclical rhythm that has developed over hundreds of millions of evolutionary years that were devoid of LAN. Light pollution as an environmental problem is gaining awareness around the world, and the World Health Organization's International Agency for Research on Cancer (IARC) has already classified working the night shift as a higher grade of cancer risk," the researchers noted.


'/>"/>

Contact: Rachel Feldman
rfeldman@univ.haifa.ac.il
972-482-88722
University of Haifa
Source:Eurekalert

Related biology news :

1. Connection between light at night (LAN) and cancer revealed in additional study
2. Brain connections break down as we age
3. Calcium connections: Basic pathway for maintaining cells fuel stores
4. Searching for causes of neural disconnection in schizophrenia
5. Connection elucidated between obesity, salt sensitivity and high blood pressure
6. Brain connections for stress -- lessons from the worm
7. Impaired brain connections traced to schizophrenia mutation
8. Lifelong memories linked to stable nerve connections
9. The food-energy cellular connection revealed
10. Ben-Gurion U. researchers reveal connection between cancer and human evolution
11. MU study finds connection between evolution, classroom learning
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/9/2017)... Australia , March 9, 2017 4Dx ... prestigious World Lung Imaging Workshop at the University of ... was invited to deliver the latest data to world ... recognised event brings together leaders at the forefront of ... in lung imaging. "The quality of ...
(Date:3/7/2017)... Brandwatch , the leading social intelligence company, today ... to uncover insights to support its reporting, help direct future ... UK,s leading youth charity will be using Brandwatch Analytics social listening ... better understanding of the topics and issues that are a priority ... ...
(Date:3/6/2017)... 6, 2017 Mintigo , the ... announced Predictive Sales Coach TM , its new ... intelligence into Salesforce. This unique AI application will ... organizations with deep knowledge of their customers and ... engagement. Predictive Sales Coach extends Mintigo,s existing customer ...
Breaking Biology News(10 mins):
(Date:4/19/2017)... ... 18, 2017 , ... Optofluidics today announced that it's changing ... company changed focus to making analytical tools for biopharmaceutical quality control. “We are ... CEO Robert Hart. Founders Bernardo Cordovez, Robert Hart and David Erickson have steered ...
(Date:4/19/2017)... ... April 19, 2017 , ... WHO: Peggy Lillis Foundation, ... education and advocacy. Founded in 2010 in memory of a single-parent mom and ... has become the most-consulted source for patient-focused information on C. diff infections in ...
(Date:4/19/2017)... , April 19, 2017  As a ... and Heroin Summit ,  Proove® Biosciences, Inc. ... genetics, environmental, and lifestyle factors to accurately predict ... University of Southern California (USC), the Interventional Pain ... Proove publish results showing that Proove Opioid Risk® ...
(Date:4/19/2017)... 19, 2017   Thermo Fisher Scientific Inc ... Procalcitonin MOnitoring SEpsis (MOSES) Study have been published ... Critical Care Medicine . Researchers from the study, ... Patients: Results From the Multicenter Procalcitonin MOnitoring SEpsis ... PCT (procalcitonin) assay to assess risk for 28 ...
Breaking Biology Technology: