Navigation Links
Comprehensive cardiogenetic testing for families of sudden unexplained death victims can save lives
Date:5/26/2009

Vienna, Austria: Relatives of a young person who dies suddenly should always be referred for cardiological and genetic examination in order to identify if they too are at risk of sudden death, a scientist told the annual conference of the European Society of Human Genetics today (Tuesday 26 May). Dr. Christian van der Werf, a research fellow at the Department of Cardiogenetics, Academic Medical Centre, Amsterdam, The Netherlands said that, although his team's research showed that inherited heart disease was present in over 30% of the families of sudden unexplained death (SUD) victims, the majority of such relatives were currently not being referred for examination.

When an individual aged 1-50 years dies suddenly, autopsy reveals an inheritable heart disease in the majority of the victims. But in approximately 20% autopsy does not reveal the cause of death. "We thought that cardiological and genetic examination of surviving first degree relatives of these SUD patients might reveal an inherited heart disease", said Dr. van der Werf.

In the largest such study to date, the team looked at the outcome of first degree relative screening in 127 families who had suffered an SUD and where either there had been no autopsy (53.8%), or the autopsy did not reveal a cause of death. The average age at death of the SUD victims was only 29.8 years old.

The initial examination of the relatives consisted of taking personal and family medical history and a resting ECG. A second cardiac autopsy of the SUD victim was undertaken if tissue had been stored and was available. Additional cardiological examinations of the relatives were performed where necessary. Genetic analysis of the associated candidate gene(s) was performed in material obtained from the deceased person or in those relatives who showed clinical abnormalities.

The researchers found inherited heart disease in 36, or 32% of the families. These results meant that doctors were
'/>"/>

Contact: Mary Rice
mary@mrcommunication.org
European Society of Human Genetics
Source:Eurekalert

Page: 1 2

Related biology news :

1. Leading researchers to reveal comprehensive dos and donts for prostate cancer
2. University of Minnesota releases first ever comprehensive report of the health of college students
3. More comprehensive analysis of Klamath River basin needed to aid decision makers
4. U. of I. librarian launches comprehensive Web database of field guides
5. Scientists launch first comprehensive database of human oral microbiome
6. Collaboration between researchers yields more comprehensive portrait of brain cancer
7. First comprehensive genomic study of common cold reveals new treatment targets
8. First comprehensive inventory of life in Antarctica
9. Scientists develop method for comprehensive proteome analysis
10. Comprehensive genetic study paves way for new blood-pressure medicines
11. Uniloc Unveils Industry-First Authentication Technology for Comprehensive Protection of Critical Infrastructure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... VIEW, Calif. , July 7, 2015 /PRNewswire/ ... biometrics market, Frost & Sullivan recognizes Credence ID, ... Sullivan Entrepreneurial Company of the Year Award. ... suite to aid in its mission of offering ... under-recognized populations globally. As Credence ID was formed ...
(Date:7/2/2015)... DUBLIN , June 25, 2015 ... has announced the addition of the "Natural ... Hybrid), Technologies (Recognition, IVR, OCR, Pattern & Image ... to their offering. The key vendors ... Google, HP, IBM Corporation, Microsoft Corporation, NetBase Solutions, ...
(Date:7/2/2015)... , July 2, 2015 Fingerprint ... FPC1025, FPC1035, FPC1145 and FPC1155 from the distributor World Peace ... of FPC,s distributors in Asia . Deliveries ... The sensors will be used by smartphone manufacturers in ... is included in the communicated revenue guidance of approximately 2,200 ...
Breaking Biology News(10 mins):Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 2Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 3Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 4Frost & Sullivan Acknowledges the Distinctive Customer-focused Attributes of Credence ID's Mobile Biometric Product Suite 5Natural Language Processing Market by Type (Rule-Based, Statistical, and Hybrid), Technologies (Recognition, IVR, OCR, Pattern & Image Recognition) - Worldwide Forecast to 2020 2FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2
... stimulation identified areas of the brain responsible for starting locomotion, ... vertebrate until now. To find this ... Biological Sciences studied a small, simple vertebrate: the Xenopus ... to initiate swimming consists of just four types of neurons. ...
... , This release is available in Spanish . ... trees in the Mediterranean region, many experts have claimed that they ... to verify this," as explained to SINC by the ecologist Bernat ... A team from this centre has now analysed the ...
... 2012 Cardium Therapeutics (NYSE Amex: CXM) today announced ... Gene & Cell Therapy (ASGCT) 15th Annual Meeting being ... in Philadelphia, PA. The new ... role in adenovector gene transfection (delivery) in mammalian hearts. ...
Cached Biology News:The millennium-old olive trees of the Iberian Peninsula are younger than expected 2Delivery of gene-therapy for heart disease boosted 100-fold; now in 100-patient trial 2
(Date:8/4/2015)... New open access, ... serving the international surgical community ... and medical information products and services, today announced the ... Open ( IJS Open ), a new ... peer-reviewed, online-only journal will make significant contributions to knowledge ...
(Date:8/4/2015)... LOS ANGELES , Aug. 4, 2015   ... announced the recent acquisition of LifeLine Cryogenics, an east ... the New York tristate area. ... tissues, and all prepaid contracts will be honored. ... of cryogenics services, offering storage of sperm, eggs, embryos, ...
(Date:8/3/2015)... 3, 2015 At the 11th ... waved the shortfall of Jude Liversage,s ... for the first time.      (Photo: ... ) The Selective Dorsal Rhizotomy (SDR) ... to carry out his wish to kick a ball ...
(Date:8/3/2015)... LOUIS (PRWEB) , ... August 03, 2015 , ... Nine ... in Iowa, Illinois and Indiana. Hosted by the Soil Health Partnership , the ... create lasting environmental benefits while potentially increasing farm productivity and income. , Brent Bible ...
Breaking Biology Technology:Elsevier Announces the Launch of International Journal of Surgery Open 2Elsevier Announces the Launch of International Journal of Surgery Open 3Elsevier Announces the Launch of International Journal of Surgery Open 4FamilyCord Announces Acquisition of LifeLine Cryogenics 2Cerebral Palsy Operation by The Portland Hospital Allows a Boy to Stand Properly for the First Time 2Cerebral Palsy Operation by The Portland Hospital Allows a Boy to Stand Properly for the First Time 3Soil Health Field Days Kick Off Throughout Midwest 2Soil Health Field Days Kick Off Throughout Midwest 3
... the market and business intelligence company, contract biomanufacturing is a significant ... of about 10 to 15%. Pharmaceutical biomanufacturing could account for more ... , ... Paris, France (PRWEB) September 15, 2008 -- Biologics ...
... the SolvayCARES Thriving Student ... Goals -, MARIETTA, Ga., Sept. 15 Solvay ... living with,cystic fibrosis (CF) through its SolvayCARES Scholarship program. ... help finance,post-secondary education. This fall, one SolvayCARES Scholarship winner,will ...
... Harvard Deploys Isilon Clustered Storage to Manage ... SEATTLE, Sept. 15 Isilon(R) Systems (Nasdaq:,ISLN), ... the Broad,Institute of MIT and Harvard, one of ... deployed Isilon IQ clustered storage to,streamline mission-critical data ...
Cached Biology Technology:CBDM.T, The Market and Business Intelligence Company Reviews The Biomanufacturing Market 2CBDM.T, The Market and Business Intelligence Company Reviews The Biomanufacturing Market 340 High-Achieving Students with Cystic Fibrosis Receive $100,000 Total in Higher Education Scholarships From SolvayCARES(SM) 240 High-Achieving Students with Cystic Fibrosis Receive $100,000 Total in Higher Education Scholarships From SolvayCARES(SM) 340 High-Achieving Students with Cystic Fibrosis Receive $100,000 Total in Higher Education Scholarships From SolvayCARES(SM) 4Isilon IQ Powers Data Storage for Next-Generation DNA Sequencing 2Isilon IQ Powers Data Storage for Next-Generation DNA Sequencing 3
Enodgenous alkaline phosphotase inhibitor. Levamisole solution is supplied in concentrated form (20x). The final concentration of levamisole in the substrate solution will be 1 mM....
LAL Chromogenic Endpoint assay...
Several Pichia pastoris strains are available to allow you to optimize expression and recovery of your protein of interest. Table 1 provides information to help you choose the appropriate strain....
...
Biology Products: