Amsterdam, The Netherlands: Complications in early pregnancy or in previous pregnancies can predict the likelihood of further problems in current or subsequent pregnancies, according to research carried out by an international group of experts.
Their findings will help clinicians to predict more easily which women might need greater care and supervision during pregnancy, as well as enabling new research to improve clinical management of such high risk patients. Improving care for pregnant women and their babies is of particular importance in countries such as The Netherlands where perinatal mortality is a cause for concern. The Netherlands has a perinatal mortality rate of 9.8 per 1000 (2006 figures) the second highest rate in Europe .
Dr Robbert van Oppenraaij told the 25th annual meeting of the European Society of Human Reproduction and Embryology in Amsterdam today (Monday) that he and his colleagues from the UK, Denmark and Spain had reviewed 75 studies carried out between 1980-2008 that looked at the impact of early pregnancy complications.
Dr van Oppenraaij, a medical doctor and PhD student in the Department of Obstetrics and Gynaecology at Erasmus MC University Medical Centre (Rotterdam, The Netherlands), said: "There were several interesting findings. To name two: firstly, we found that after any first trimester complication or event, the risk of preterm or very preterm delivery is increased in the subsequent or ongoing pregnancy; secondly, we found that increased risks of adverse obstetric outcome are, in all cases, related to the severity or recurrence, or both, of the first trimester complication or event. To our knowledge, this is the first comprehensive review in which the impact of more than one first trimester complication on adverse obstetric outcome has been investigated systematically."
The researchers found that a history of one or more miscarriages nearly doubled the risk in an ongo
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European Society for Human Reproduction and Embryology