Navigation Links
Common food supplement fights degenerative brain disorders
Date:5/21/2013

Widely available in pharmacies and health stores, phosphatidylserine is a natural food supplement produced from beef, oysters, and soy. Proven to improve cognition and slow memory loss, it's a popular treatment for older people experiencing memory impairment. Now a team headed by Prof. Gil Ast and Dr. Ron Bochner of Tel Aviv University's Department of Human Molecular Genetics have discovered that the same supplement improves the functioning of genes involved in degenerative brain disorders, including Parkinson's disease and Familial Dysautonomia (FD).

In FD, a rare genetic disorder that impacts the nervous system and appears almost exclusively in the Ashkenazi Jewish population, a genetic mutation prevents the brain from manufacturing healthy IKAP proteins which likely have a hand in cell migration and aiding connections between nerves leading to the early degeneration of neurons. When the supplement was applied to cells taken from FD patients, the gene function improved and an elevation in the level of IKAP protein was observed, reports Prof. Ast. These results were replicated in a second experiment which involved administering the supplement orally to mouse populations with FD.

The findings, which have been published in the journal Human Molecular Genetics, are very encouraging, says Prof. Ast. "That we see such an effect on the brain the most important organ in relation to this disease shows that the supplement can pass through the blood-brain barrier even when administered orally, and accumulate in sufficient amounts in the brain."

Slowing the death of nerve cells

Already approved for use as a supplement by the FDA, phosphatidylserine contains a molecule essential for transmitting signals between nerve cells in the brain. Prof. Ast and his fellow researchers decided to test whether the same chemical, which is naturally synthesized in the body and known to boost memory capability, could impact th
'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Commonly used herbicides seen as threat to endangered butterflies
2. Common North American frog identified as carrier of deadly amphibian disease
3. Researchers uncover molecular pathway through which common yeast becomes fungal pathogen
4. New research about facial recognition turns common wisdom on its head
5. Commonly used diabetes drug may help to prevent primary liver cancer
6. Loyola study debunks common myth that urine is sterile
7. Dental X-rays linked to common brain tumor
8. Women & Infants participating in study of treatment of common viral infection in pregnancy
9. Clusters of cooperating tumor-suppressor genes are found in large regions deleted in common cancers
10. Modest alcohol intake associated with less inflammation in patients with common liver disease
11. Sulphur and iron compounds common in old shipwrecks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... the growing mobile commerce market and creator of the ... Card Alliance and the EMV Migration Forum.  ... Card Alliance Latin America (SCALA) Chapter provides NXT-ID, Inc. ... leaders promoting adoption of smart card technology. ...
(Date:8/17/2015)...  NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... growing mobile commerce market and creator of the Wocket® ... 2015. The new marketing campaign is being spearheaded by ... Group ( http://amplitudemarketing.com/ ) and TPMG ( http://tmpg.com/ ). ... retail driven marketing and brand awareness and has a ...
(Date:8/12/2015)... 2015  Synaptics Inc. (NASDAQ: SYNA ), ... announced that four of its fingerprint ID products, ... been named FIDO Certified™ by the Fast IDentity ... Synaptics, Natural ID™ fingerprint solutions are fully compliant ... standard and are interoperable among other products and ...
Breaking Biology News(10 mins):NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 2NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 3NXT-ID, Inc. Joins Smart Card Alliance and EMV Migration Forum 4NXT-ID, Inc. Launches Sales Campaign for Wocket Smart Wallet with Award Winning Marketing Team 2NXT-ID, Inc. Launches Sales Campaign for Wocket Smart Wallet with Award Winning Marketing Team 3Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 2Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 3
... the most of the spectacular traits in nature: the wild ... walruses and antlers on moose. Sexual conflict the battle ... be a particularly potent force in driving the evolution traits ... processes responsible for producing such traits are not well understood, ...
... of brain activity in the rat brain that play ... and decision-making. The discovery, which builds on the team,s ... and post-traumatic stress syndrome. The researchers previously identified ... brain region critical for memory storage. The patterns sometimes ...
... essential for making informed choices, suggests a study in ... scientists funded by the National Institutes of Health. The ... by selectively suppressing replay encoded as split-second bursts ... performing a maze task., "It appears to ...
Cached Biology News:Biologists turn back the clock to understand evolution of sex differences 2Rats recall past to make daily decisions 2Rats recall past to make daily decisions 3Awake mental replay of past experiences critical for learning 2Awake mental replay of past experiences critical for learning 3
(Date:8/27/2015)... TRIANGLE PARK, N.C. , Aug. 27, 2015 ... on the decision by FedEx, UPS and The ... of certain biological specimens classified as ,select agents, ... and long history of handling these sensitive shipments. ... knowledge of global transportation regulations, trained and certified ...
(Date:8/26/2015)... KS (PRWEB) , ... August 26, 2015 , ... ... Biologic Solutions, announces today that a second US laboratory is to open in ... accordance with the continued partnership and long-term growth of research and development through ...
(Date:8/26/2015)... N.J. , Aug. 26, 2015  Roka Bioscience, ... focused on providing advanced testing solutions for the detection ... CEO will present at the Sidoti & Company Emerging ... conference will be held at the New York Marriott ... presentation will be available through the investor relations section ...
(Date:8/26/2015)... , Aug. 26, 2015  The Diabetes Research ... University of Miami Miller School of Medicine, announced ... trial to test for the first time a ... completed.  This FDA approved Phase I/II study builds ... and is an important first step toward the ...
Breaking Biology Technology:Marken Ensures Safe Transportation Of Select Agents And Toxins 2MediVet Biologics Animal Health Secures Additional Laboratory Facility in Manhattan, Kansas 2MediVet Biologics Animal Health Secures Additional Laboratory Facility in Manhattan, Kansas 3Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 2Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 3Diabetes Research Institute Successfully Transplants First Patient In Pilot BioHub Trial 4
... note: , ,As promised, our latest e-mail newsletter contains the ... has increased from around 30,000 visitors a month to over ... than a few stories weve paid attention to what drew ... who has already registered for Fusion2006. The conference isnt until March ...
... Corporation for Assigned Names and Numbers, is all about a ... golden key is a name on the net called a ... key management system so that billions of single domain name ... problem. After all, without this access, the Internet has no ...
... researchers led by stem-cell pioneer James Thomson have ... and better-defined lab conditions than previous cultures. , ... could pave the way for stem-cell treatments with ... contamination. Growing stem cells in the lab requires ...
Cached Biology Technology:When will the Internet be divided among nations? 2When will the Internet be divided among nations? 3When will the Internet be divided among nations? 4When will the Internet be divided among nations? 5
... Green II RNA gel stain is a ... fluorescence when bound to RNA and low background ... either formaldehyde/agarose or polyacrylamide gels using laser scanners ... minigels. A 500 µL unit size (S-7564) and ...
Sirtuin 7 (SIRT7) Rabbit anti-Human Polyclonal Antibody Immunogen: Synthetic peptide - KLH conjugated Family: Other Recommended Storage: Long term: -20C; Short term: +4C...
... taking automated patch clamping to a new and ... generate thousands of high quality data points daily, ... ion channel drug discovery and safety testing. Automated ... by conventional patch clamping can now be applied ...
... for RNA aptamer screening and binding optimization ... Paraflo microfluidic on-chip synthesis platform. These microarrays ... DNA/RNA Aptamer Microarray Service. Probe ... Microarray contains greater than 1500 known aptamer ...
Biology Products: