Navigation Links
Common aquatic animals show extreme resistance to radiation
Date:3/25/2008

CAMBRIDGE, Mass., March 25, 2008 -- Scientists at Harvard University have found that a common class of freshwater invertebrate animals called bdelloid rotifers are extraordinarily resistant to ionizing radiation, surviving and continuing to reproduce after doses of gamma radiation much greater than that tolerated by any other animal species studied to date.

Because free radicals such as those generated by radiation have been implicated in inflammation, cancer, and aging in higher organisms, the findings -- published this week in the Proceedings of the National Academy of Sciences by Harvard's Matthew Meselson and graduate student Eugene Gladyshev -- could stimulate new lines of research into these medically important problems.

"Bdelloid rotifers are far more resistant to ionizing radiation than any of the hundreds of other animal species for which radiation resistance has been examined," says Meselson, Thomas Dudley Cabot Professor of the Natural Sciences in Harvard's Faculty of Arts and Sciences. "They are able to recover and resume normal reproduction after receiving a dose of radiation that shatters their genomes, causing hundreds of DNA double-strand breaks which they are nevertheless able to repair."

Meselson and Gladyshev found that the bdelloid rotifers Adineta vaga and Philodina roseola remained reproductively viable after doses of radiation roughly five times greater than other classes of rotifers and other animals could endure.

Such radiation resistance appears not to be the result of any special protection of DNA itself against breakage, the researchers say, but instead reflects bdelloid rotifers' extraordinary ability to protect their DNA-repairing machinery from radiation damage.

Roughly a half-millimeter in size and commonly observed under microscopes in high-school biology classes, bdelloid rotifers are highly unusual in several regards: They appear to be exclusively asexual, have relatively few transposable genes, and can survive and reproduce after complete desiccation at any stage of their life cycle. Meselson and Gladyshev hypothesize that it's this last property that explains bdelloids' apparently unique resistance to radiation.

Bdelloid rotifers have been widely studied since at least 1702, when the renowned Dutch scientist and microscopy pioneer van Leeuwenhoek added water to dust retrieved from a rain gutter on his house and observed the organisms in the resulting fluid. He subsequently described the creatures in a letter to Britain's Royal Society, which still counts an envelope of van Leeuwenhoek's rain-gutter dust among its holdings.


'/>"/>

Contact: Steve Bradt
steve_bradt@harvard.edu
617-496-8070
Harvard University
Source:Eurekalert

Related biology news :

1. A common genetic mechanism discovered in nitrogen-fixing plants
2. Stakeholders use science to find common ground on wood supply from forests
3. Europes most common genetic disease is a liver disorder
4. Blue-eyed humans have a single, common ancestor
5. Disrupting common parasites ability to talk to each other reduces infection
6. U of M research finds disordered eating less common among teen girls who regularly eat family meals
7. Bacterial infections in premature babies more common than previously realized
8. Tiny dust particles from Asian deserts common over western United States
9. Cell response to stress signals predicts tumors in women with common pre-breast cancer
10. Drug commonly used to treat bipolar disorder dramatically increases lifespan in worms
11. UCI researchers restore memory process in most common form of mental disability
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2016)... , España y TORONTO , 19 de diciembre ... Northern Biologics Inc. que permitirá el desarrollo acelerado de MSC-1, un ... en varios tipos de tumor en 2017, con múltiples sitios previstos ... ... clase con objetivo en el factor inhibidor de leucemia (LIF), una ...
(Date:12/15/2016)... , Dec. 15, 2016   WaferGen Bio-systems, ... held genomics technology company, announced today that on December ... Qualifications Department of The Nasdaq Stock Market LLC which ... bid price of WaferGen,s common stock had been at ... WaferGen has regained compliance with Listing Rule 5550(a)(2) of ...
(Date:12/12/2016)... 12, 2016  Researchers at Trinity College, Dublin, ... by combining the material with Silly Putty. The mixture ... detector able to sense pulse, blood pressure, respiration, ... The research team,s findings were ... here:  http://science.sciencemag.org/content/354/6317/1257 ...
Breaking Biology News(10 mins):
(Date:1/24/2017)... , January 23, 2017 ... Model Market by Type (Genetic, Cell-based (CD34, PBMC, BLT)), ... End User (Pharmaceutical & Biotech Companies, CRO) - Global ... the global Humanized Mouse Model Market for the forecast ... to reach USD 116.0 Million by 2021 from USD ...
(Date:1/24/2017)... , Jan. 23, 2017 /PRNewswire/ - BioAmber Inc. (NYSE: ... entered into an underwriting agreement with Rodman & Renshaw, ... LLC, as sole book running manager and representative of several ... on a firm commitment basis a minimum of 2,105,264 ... warrants to purchase a minimum of 1,052,632 shares of ...
(Date:1/23/2017)... N.J. , Jan. 23, 2017   Enteris ... feasibility study agreement with Sanofi to leverage ... delivery platform, Peptelligence™, to develop an oral formulation of ... Joel Tune , Chief Executive Officer and Executive ... is further validation of the tremendous value our Peptelligence ...
(Date:1/23/2017)... ... January 23, 2017 , ... ... Vice President, Preclinical Safety and Senior Director, Safety Pharmacology. Dr. Thomas earned ... , Dr. Thomas’ career as an academic and industry preclinical drug developer ...
Breaking Biology Technology: