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Combined molecular study techniques reveal more about DNA proteins
Date:3/2/2011

Ha and their group to measure both a protein's motion sensitive to translocation as small as one DNA base pair, a distance of only a few angstroms and also conformational changes as it acts. This can reveal details about its mechanism that would not have been accessible before.

"It was a major technical challenge, but the final product is a one-of-a-kind instrument with unique capabilities," Chemla said. "It's like taking a rudimentary, real-time 'movie' of what individual molecules are doing."


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Contact: Liz Ahlberg
eahlberg@illinois.edu
217-244-1073
University of Illinois at Urbana-Champaign
Source:Eurekalert

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