"These compounds work at very low concentrations at the parts per trillion or parts per quadrillion level and when you mix them together they affect estrogenic signaling differently and more dramatically than they do individually," Watson said. "We need to pay attention to this, because estrogens influence so many things in both males and females reproduction, the immune system, metabolism, bone growth, all sorts of important biological functions."
Studies have detected measurable levels of bisphenol A and bisphenol S in the urine of more than 90 percent of Americans. According to Watson, modern humans are exposed to dozens of xenoestrogens more or less continually.
"These things are all over the environment, and we need to know what they do so we can start figuring out what we need to change," Watson said. "They're probably disrupting and confusing hormones in people, and it's important to find a way to prevent that as soon as we can. We need to test these compounds for their hormone-disrupting activities before they are put into products, so we can redesign for safety very early in the process."
|Contact: Jim Kelly|
University of Texas Medical Branch at Galveston