The Louisa Gross Horwitz Prize Lectures, presentations by the scientists, will be held on Monday, November 19. Dr. Gall will give his lecture at 10 a.m. in the Roone Arledge Cinema, Alfred Lerner Hall (2920 Broadway at W. 115th St.) at Columbia Universitys Morningside Campus. Dr. Blackburn will give her lecture at 1:30 p.m., followed by Dr. Greiders lecture at 3 p.m., both in the College of Physicians & Surgeons building (650 West 168th Street), Alumni Auditorium, at Columbia University Medical Center. For more information about the lectures, visit http://www.cumc.columbia.edu/events/deanlectures/.
These researchers representing three generations of science passed down from teacher to student have all contributed to the fundamental understanding of the process of aging, a body of work of enormous depth and value that may lead us to the discovery of keys to longevity and mortality, said Andrew R. Marks, M.D., chair of the Horwitz Prize Committee at Columbia University. Dr. Marks is the Wu Professor of Molecular Cardiology and chairman of the Department of Physiology and Cellular Biophysics at Columbia University College of Physicians and Surgeons.
Pursuit of Basic Questions about Cell Workings Leads to Insights into Aging & Cancer
Work by these researchers led to discovery of the structure of telomeres and telomerase. It was started to answer two very fundamental questions: what prevents the cell from destroying its own chromosomes, and what prevents the chromosomes from shrinking.
Before the late 1970s and 1980s when the prize-winning work was performed, there were two mysteries about chromosomes. One, chromosomes are long lines of DNA so they have two ends, but cells recognize accidental breaks in chromosomes by their broken ends why dont the cells try to repair the ends of chromosomes" And even if they did, this might ha
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Columbia University Medical Center