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Columbia honors Philipp Scherer for helping to define body fat as major endocrine organ
Date:11/18/2013

cells from patients who have already developed the disease, leaving unclear which defects cause disease and which are a consequence of disease. With a new mouse model that contains the human immune system of the human donor, Dr. Danzl plans to identify the defects in immune regulation that contribute to type 1 diabetes. Her aim is to use this personalized immune mouse model to find new treatment strategies for people with type 1 diabetes. Dr. Danzl is a postdoctoral research fellow in the laboratory of Megan Sykes, MD, the Michael J. Friedlander Professor of Medicine, professor of microbiology & immunology and of surgical sciences (in surgery), and director of the Columbia Center for Translational Immunology.

The Berrie Fellowship provides an opportunity for intensive training in a biomedical research laboratory. Recipients over the past 15 years have gone on to outstanding careers in diabetes research.

Russell Berrie Foundation Scholar in Diabetes Research Award

The Russell Berrie Foundation Scholar in Diabetes Research Award was established in 2013 to enable international researchers to work for up to two years in laboratories affiliated with the Naomi Berrie Diabetes Center. Luis Arnes, PhD, of Spain, and Ernico Bertaggia, PhD, of Italy, are the first recipients of this award. They will share a $300,000 grant.

Both type 1 and type 2 diabetes ultimately result in beta-cell loss and/or dysfunction. Replacing lost beta cells with new ones generated from stem cells or induced pluripotent cells is a promising therapeutic approach; however scientists have not been able to create fully functional beta cells with high efficiency. Dr. Arnes is studying how a recently discovered group of RNA molecules in the pancreas regulates beta cell development, and whether those RNAs can improve researchers' ability to generate beta cells suitable for the treatment of patients with type 1 diabetes. Dr. Arnes is a postdoctoral research fellow
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Contact: Elizabeth Streich
eas2125@cumc.columbia.edu
212-305-3689
Columbia University Medical Center
Source:Eurekalert  

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