Navigation Links
Columbia geneticists uncover new gene involved in determining hair texture and density in humans
Date:2/25/2008

NEW YORK (Feb. 25, 2008) A Columbia University Medical Center research team has discovered a new gene involved in determining hair texture in humans. The team's genetic analysis demonstrated that mutations in a gene, known as P2RY5, cause hereditary "woolly hair" hair that is coarse, dry, tightly curled and sparse.

"Our findings indicate that mutations in the P2RY5 gene cause hereditary woolly hair. This is significant as it represents the discovery of the first new gene whose primary function seems to be the determination of hair texture in humans," said lead author Angela M. Christiano, Ph.D., the Richard and Mildred Rhodebeck Professor of Dermatology and Genetics & Development, at the Columbia University College of Physicians and Surgeons.

"This genetic finding may inform the development of new treatments for excessive or unwanted hair, or potentially hair growth." added Dr. Christiano.

Findings were published in an online edition of Nature Genetics at 1 p.m. EST on Sunday, February 24, 2008. The paper will appear in the journal's March print issue.

The genetic causes of hair texture in humans are largely unknown. Hair shafts emerge from the surface of the skin and display wide variability in texture and color among individuals of different populations around the world.

Since research has shown that woolly hair was common among Pakistani families, Dr. Christiano and her colleagues set out to determine why this type of hair was specific to this group of people. They hoped that finding the genetic basis of this unique type of hair would help them to distinguish other genetic hair types, and to learn more about the genetic underpinnings of different hair textures.

Much of Dr. Christiano's research has focused on dermatologic variants found in Pakistani families, as they often represent ideal subjects for genetic analyses as they tend to be relatively homogeneous, with close-knit families that tend to
'/>"/>

Contact: Elizabeth Streich
eas2125@columbia.edu
212-305-6535
Columbia University Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Columbia to award 2007 Horwitz Prize to three generations of teacher-student scientists
2. 3 Columbia University Medical Center faculty elected to Institute of Medicine
3. Columbia researchers: Growth of CT scan use may lead to significant public health problem
4. Plant geneticists find veritas in vino
5. St. Jude influenza survey uncovers key differences between bird flu and human flu
6. 454 Sequencing uncovers a genetic basis for different social behaviors in wasp
7. Joslin researchers uncover potential role of leptin in diabetes
8. Agent that triggers immune response in plants is uncovered
9. UD plant biologists uncover top wetland plants hidden weapon
10. Massive microRNA scan uncovers leads to treating muscle degeneration
11. Scientists uncover how hormones achieve their effects
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... study (HPV-023; NCT00518336) shows the sustained efficacy, ... virus (HPV) vaccine Cervarix. Women vaccinated with ... more than nine years, and vaccine efficacy ... is the longest follow-up report for a ... for the full paper. , HPV ...
(Date:7/31/2014)... 100 percent of animal models against the highly infectious ... an intestinal disease that kills approximately 30,000 Americans annually. ... Infection and Immunity . , In the study, ... the purified toxins produced by C. difficile , ... laboratory model that mimics the human disease, after only ...
(Date:7/31/2014)... that the U.S. surgeon general issued a 101-page report ... State University published a paper breaking new ground on ... responds when exposed to ultraviolet (UV) light. , ... the UV rays found in sunlight. This damage can ... diseases. , "Our paper advances foundational knowledge about ...
Breaking Biology News(10 mins):Sustained efficacy, immunogenicity, and safety for GlaxoSmithKline's HPV vaccine 2Sustained efficacy, immunogenicity, and safety for GlaxoSmithKline's HPV vaccine 3C. difficile vaccine proves safe, 100 percent effective in animal models 2New paper describes how DNA avoids damage from UV light 2New paper describes how DNA avoids damage from UV light 3
... Hold the Key to Muscular Dystrophy , A mutation ... been known to be associated with muscular dystrophy, but ... unknown. Lorenzo Puri, M.D., Ph.D. and colleagues have discovered ... amount of the histone deacetylase enzyme, HDAC2. Increased HDAC2 ...
... ever wondered why it seems like the littlest things make ... a spilled glass of water can lead to a fist ... three words to explain why people may be evolutionarily inclined ... sex. Although hostility or belligerent acts might not immediately ...
... long known that dinosaurs had tiny brains, but they had ... new study by Ohio University researchers Lawrence Witmer and Ryan ... heads than expected. By using CT scans, the scientists were ... show a clearer picture of the physiology of the airways. ...
Cached Biology News:The Burnham buzz 2U of Minnesota researcher finds link between aggression, status and sex 2CT scans reveal that dinosaurs were airheads 2CT scans reveal that dinosaurs were airheads 3
(Date:7/31/2014)... 2014 Nearly 20,000 medical professionals and healthcare ... & Clinical Lab Expo in Chicago ... in diagnostic research and technology that will advance medicine ... As of Wednesday, July 30, more than 19,500 attendees ... Clinical Lab Expo, with more than 10,000 of these ...
(Date:7/31/2014)... the sound-processing part of the mouse brain in a ... trees in view. Their imaging technique allows zooming in ... and it enabled the team to watch brain cells ... results, which represent a step toward better understanding how ... the journal Neuron . , In the past, ...
(Date:7/31/2014)... , July 31, 2014 Rogne Bioscience, a ... Bay Area , has acquired a licence to ... commercialisation company. The potent anti-inflammatory activity of the peptides ... the University of Oxford,s Sir William Dunn School ... has raised over $1.5 million in seed financing, is ...
(Date:7/31/2014)... July 31, 2014 Research and Markets ... Genomics Market 2014-2018" report to their offering. ... is the study of the genetic material or genomes ... strong basis for the discovery and development of diagnostic ... or health conditions. Genomics is supported by three major ...
Breaking Biology Technology:Research on Digital Health, Alzheimer's, Ebola Draws Nearly 20,000 Attendees to 2014 AACC Annual Meeting & Clinical Lab Expo 2Research on Digital Health, Alzheimer's, Ebola Draws Nearly 20,000 Attendees to 2014 AACC Annual Meeting & Clinical Lab Expo 3New mapping approach lets scientists zoom in and out as the brain processes sound 2Oxford licenses anti-inflammatory peptides to San Francisco Bay Area start-up 2Oxford licenses anti-inflammatory peptides to San Francisco Bay Area start-up 3Global Genomics Market 2014-2018: Key Vendors are F. Hoffmann-La Roche, Life Technologies, Qiagen and Illumina 2
... Biosciences,Corporation (Nasdaq: MATK ) today announced that ... Wilmington, Delaware, has ruled on various,post-trial motions and ... the defendants in the patent infringement suit brought ... Nutrition Specialties &,Food Ingredients GmbH. The suit involves ...
... Nov. 1 ThermoGenesis,Corp. (Nasdaq: KOOL ), a ... store, and administer therapeutic doses of,adult stem cells for ... financial results for the fiscal first quarter ended September,30, ... Call and Webcast Management will host a conference ...
... technical feasibility of ... ... TSX symbol: SBS, CALGARY, Nov. 1 /PRNewswire-FirstCall/ - ... for metabolic and cardiovascular diseases, today announced its,2007 third quarter operational ...
Cached Biology Technology:Martek to Obtain Permanent Injunction Against Lonza in U.S. Patent Infringement Suit; Jury Verdict on Infringement of Two of Three Patents Upheld by Judge 2Martek to Obtain Permanent Injunction Against Lonza in U.S. Patent Infringement Suit; Jury Verdict on Infringement of Two of Three Patents Upheld by Judge 3ThermoGenesis Corp. to Announce First Quarter Fiscal 2008 Results on November 8, 2007 2ThermoGenesis Corp. to Announce First Quarter Fiscal 2008 Results on November 8, 2007 3SemBioSys announces 2007 third quarter results 2SemBioSys announces 2007 third quarter results 3SemBioSys announces 2007 third quarter results 4SemBioSys announces 2007 third quarter results 5SemBioSys announces 2007 third quarter results 6SemBioSys announces 2007 third quarter results 7SemBioSys announces 2007 third quarter results 8SemBioSys announces 2007 third quarter results 9SemBioSys announces 2007 third quarter results 10SemBioSys announces 2007 third quarter results 11SemBioSys announces 2007 third quarter results 12
More cell-permeant than acridine orange....
HistoScan HRP Kit Universal Goat Kit...
4',6-Diamidino-2-phenylindole dihydrochloride...
...
Biology Products: