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Columbia awards 2012 Naomi Berrie Award to Drs. Christophe Benoist & Diane Mathis
Date:11/19/2012

biology at Harvard Medical School, and members of the National Academy of Sciences.

"This is the first time that this award has been presented to two investigators simultaneously," said Dr. Leibel. "The selection of these long-standing collaborators recognizes their major insights into the mechanisms by which T cells assault insulin-producing cells in the pancreas and cause type 1 diabetes."

Hongxia Ren, PhD, the junior award recipient, is an associate research scientist in the laboratory of Domenico Accili, MD in the Naomi Berrie Diabetes Center. Based on her discovery that the gene Gpr17 acts as a nutrient sensor and appetite regulator, Dr. Ren is currently examining the hypothesis that signaling activity of Gpr17 in AgRP, neurons in the hypothalamus that are critical for initiating food intake and maintaining energy homeostasis, are involved in regulating satiety and metabolism. If this hypothesis is correct, specific G-protein-coupled receptors could provide therapeutic targets in the treatment of obesity and its comorbidities. She is also exploring the role of liver/central nervous system interactions in the pathogenesis of diabetes.

Established by the Russell Berrie Foundation in 2000, the Naomi Berrie Award for Outstanding Achievement in Diabetes Research promotes and rewards outstanding achievement in the field, while supporting the careers of promising young diabetes investigators. Each year, the recipienta senior scientist outside Columbia who has made major contributions to diabetes researchis given $100,000 to support a two-year research fellowship for a student or research fellow in his or her laboratory. This year Drs. Benoist and Mathis will share this prize. The second $100,000 award supports a research fellow at Columbia.


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Contact: Karin Eskenazi
ket2116@columbia.edu
212-342-0508
Columbia University Medical Center
Source:Eurekalert

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