Navigation Links
Columbia University scientist devises new way to more rapidly generate bone tissue
Date:12/15/2008

NEW YORK (Dec. 15, 2008) Using stem cell lines not typically combined, researchers at Columbia University Medical Center have designed a new way to "grow" bone and other tissues.

The inability to foster angiogenesis a physiological process involving the growth of new blood vessels from pre-existing vessels has been a major roadblock in tissue regeneration. Previous approaches have included the use of angiogenic growth factors and the fabrication of artificial blood vessels. However, there are problems associated with these approaches. Among these problems: artificially fabricated blood vessels do not readily branch out and network with host blood vessels, and blood vessels induced by angiogenic growth factors tend to be immature and "leaky."

To overcome these obstacles, a team of Columbia researchers has co-transplanted hematopoietic and mesenchymal stem/progenitor cells to promote the regeneration of vascularized tissues. What they found was that the tissue regenerated in bone more rapidly than when either type of stem cell was used alone.

The work by Jeremy Mao, DDS, Ph.D., published today in the Public Libraries of Science, takes a new approach: rarely have mesenchymal and hematopoietic cells been delivered in combination for the healing of defects and the treatment of diseases partially due to the separate research communities in which these two cell groups are studied.

"Dr. Mao's research in tissue engineering represents the fruits of interdisciplinary science. His work has relevance for oral health care, as well as many other health care disciplines," said Dr. Ira Lamster, Dean of the Columbia University College of Dental Medicine.

Dr. Mao and colleagues demonstrated that when human mesenchymal stem/progenitor cells were seeded in micropores of 3D calcium phosphate scaffolds, followed by infusion of gel-suspended CD34+ hematopoietic cells, greater vascularization was seen in mice than when mesenchymal cells
'/>"/>

Contact: Alex Lyda
mal2133@columbia.edu
212-305-0820
Columbia University Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Salmon smolt survival similar in Columbia and Fraser rivers
2. Similar survival rates for Pacific salmon in Fraser, Columbia Rivers raises new questions
3. Columbia to award 2008 Horwitz Prize to Arthur Horwich & Ulrich Hartl for cellular protein folding
4. Columbia geneticists uncover new gene involved in determining hair texture and density in humans
5. Columbia researchers: Growth of CT scan use may lead to significant public health problem
6. 3 Columbia University Medical Center faculty elected to Institute of Medicine
7. Columbia to award 2007 Horwitz Prize to three generations of teacher-student scientists
8. Queens University Belfast plays leading role in Europe-wide tests for safer food
9. Wii bit of fun at Rice University has serious intent
10. Rice University study finds possible clues to epilepsy, autism
11. World Energy Outlook to be presented at Rice University Dec. 9
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/26/2015)... PUNE, India , August 26, 2015 ... (Two, Three, Four, and Five Factor), Application (Travel & ... and Geography - Global Forecast to 2020", published by ... 9.60 Billion by 2020, growing at a CAGR of ... 71 Tables and 82 F igures spread through ...
(Date:8/24/2015)... 24, 2015 The consulting company Frost ... biometrics manufacturer DERMALOG and its customized solutions and products for ... Company of the Year Award". DERMALOG is particularly successful with ...   -Cross reference: Picture is available at AP ... On Thursday evening, in South Africa,s ...
(Date:8/20/2015)... Aug. 20, 2015 The wearable technology ... are active and healthy. However, wearable technology has ... environment to help improve diagnostic capabilities and therapeutic ... the Wearable Technologies Conference 2015 , where ... for wearables in healthcare.    "Over ...
Breaking Biology News(10 mins):Multi-Factor Authentication Market Worth 9.60 Billion USD by 2020 2Multi-Factor Authentication Market Worth 9.60 Billion USD by 2020 3Multi-Factor Authentication Market Worth 9.60 Billion USD by 2020 4Multi-Factor Authentication Market Worth 9.60 Billion USD by 2020 5Frost & Sullivan Honors DERMALOG with Biometrics Prize for Achievements in Africa 2Frost & Sullivan Honors DERMALOG with Biometrics Prize for Achievements in Africa 3Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 2Leaf Healthcare Releases Video from Wearable Technology Conference on New Applications for Wearables in the Hospital Environment 3
... submicroscopic aberration in a particular region of human ... a variety of developmental disorders in children. The ... moderate mental retardation, growth retardation, learning disabilities, seizures, ... head size, unusual facial features, hand deformities, or ...
... speakers and panelists from the U.S. Centers for Disease ... AIDS Institute, and the Semel Institute for Neuroscience and ... which genetics, race and health care disparities prevent or ... the UCLA AIDS Institute, will include a press conference ...
... set of stripy legs in a camera trap photo snapped ... researchers from the Wildlife Conservation Society. The legs belong to ... Democratic Republic of Congo,s Virunga National Park, despite over a ... is the first time this species has been captured on ...
Cached Biology News:Aberrations in region of chromosome 1q21.1 associated with broad range of disorders in children 2Aberrations in region of chromosome 1q21.1 associated with broad range of disorders in children 3Photo reveals rare okapi survived poaching onslaught 2
(Date:8/27/2015)... ... 27, 2015 , ... Capital Edge Consulting , a nationwide consulting firm ... announce their ranking as one of the top 5000 companies listed on the ... the nation. , “It is truly an honor to be recognized as one of ...
(Date:8/27/2015)... - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the Company") today announced ... 2015. Biorem,s complete second quarter financial statements and MD&A have been ... except earnings per shareThree-months ended , Six -months endedJune 30 , ... , 2014 Revenue , 4,709 , ... , 1,656 , 56 , 3,188 ...
(Date:8/27/2015)... Aug. 27, 2015 In response to ... UPS and The US Postal Service to no ... as ,select agents, by the CDC, Marken reaffirmed ... these sensitive shipments. Marken uses its ... trained and certified personnel to ensure the safe ...
(Date:8/26/2015)... ... August 26, 2015 , ... Lee Biosolutions, a ... development and manufacture of highly valued cardiac markers used in early detection of ... with protein chemistry has led to the development and commercialization of important cardiac ...
Breaking Biology Technology:Capital Edge Consulting Makes Inc. 5000 List of America’s Fastest-Growing Private Companies 2Capital Edge Consulting Makes Inc. 5000 List of America’s Fastest-Growing Private Companies 3BIOREM Reports $718,000 Net Earnings for the Second Quarter 2BIOREM Reports $718,000 Net Earnings for the Second Quarter 3Marken Ensures Safe Transportation Of Select Agents And Toxins 2Lee Biosolutions Announces Increased Investment in the Development and Manufacturing of Biomarkers Used in Early Detection Of Heart Disease 2
... Milestone System; Braden River Equine Begins Next 1,000 Eklin DR Systems ... ... and LAKE SUCCESS, N.Y., Sept. 18 ,Digital radiography (DR) has been ... systems installed throughout,the world. Eklin Medical Systems, a global leader in ...
... Tengion Neo-Bladder Augment(TM) Featured in ... September Issue of Regenerative Medicine, EAST ... regenerative medicine company focused on the development of,neo-organs and ... study conducted with its Tengion Neo-Bladder,Augment(TM) were published in ...
... 18 More than 60 physicians credentialed,to practice at ... were honored by D Magazine at its annual Best ... of the premier specialty surgical,hospitals in the country and ... of,our physicians again included in this prestigious list. The ...
Cached Biology Technology:Eklin Medical Surpasses 1,000th RapidStudy(R) Digital Radiography System Installation Featuring Canon DR Technology 2Eklin Medical Surpasses 1,000th RapidStudy(R) Digital Radiography System Installation Featuring Canon DR Technology 3Eklin Medical Surpasses 1,000th RapidStudy(R) Digital Radiography System Installation Featuring Canon DR Technology 4Tengion Scientists Publish Positive Preclinical Findings With Neo-Organ Demonstrating Long-term Durability and Growth With Skeletal Maturation 2Annual List of 'Best Doctors in Dallas' Showcases Texas Institute for Surgery Physicians 2
... are ideal for storage and transport of ... racks withstand extreme temperatures, making them an ... also be autoclaved for use in sterile ... accommodates 0.5ml microcentrifuge tubes, the other 1.5ml ...
... Signet offers the most comprehensive, ... requirements. We have incorporated unprecedented quality ... capabilities. This includes proven detection chemistries ... to the TechMate protocol. It also ...
... of universal lysis buffer, PCR mix, DNA ... 25 l volume PCR reactions. This system ... or positive rod and coccus bacteria, such ... Staphylococcus Aureus, Streptococcus Agalactiae, and etc. With ...
...
Biology Products: