Navigation Links
Cold Spring Harbor Laboratory's lung cancer research program awarded $100,000 grant
Date:1/10/2008

Cold Spring Harbor, NY Cold Spring Harbor Laboratorys (CSHL) researcher Raffaella Sordella, Ph.D. was awarded $100,000 by Joans Legacy: The Joan Scarangello Foundation to Conquer Lung Cancer. The two-year grant will fund CSHLs pioneering lung cancer research involving a new class of genetic mutations that appear to be a trigger in non-small cell lung cancer, the leading cause of cancer deaths in the United States.

The mutations, called epidermal growth factor receptors (EGFR), are more common in women than in men. This raises the possibility that interactions between EGFR and estrogen might be important in the development of tumors harboring EGFR mutations.

Our research will build upon preliminary observations that estrogen provokes EGFR activity in non-small cell lung cancer, Sordella said. We hypothesize that normal estrogen levels prevent the development of tumors harboring EGFR genetic abnormalities, tumors harboring these genetic lesions may arise when estrogen levels decrease, as is the case with post-menopausal women.

The Joans Legacy grant awarded to Dr. Sordella is part of a $1.2 million grant designated by the Foundation for twelve researchers conducting innovative projects at nationally recognized institutions like Cold Spring Harbor Laboratory. Over the past five years, the Foundation has awarded 36 grants, including those made in collaboration with other research-focused lung cancer nonprofits. A 2005 Joans Legacy grant awarded to CSHL researcher David Mu, Ph.D. enabled his discovery of three new genes that cause lung cancer.

In 2007, we received a record-breaking 65 proposals for funding. This overwhelming response demonstrates how funding availability can stimulate the scientific community to focus efforts on this often neglected disease with its low survival rates, said Joans Legacy President Mary Ann Tighe.

Lung cancer is the number one cancer killer in the United States, taking more than 160,000
'/>"/>

Contact: Jim Bono
bono@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory
Source:Eurekalert

1

GOOD

Page: 1 2

Related biology news :

1. Springer increases publishing activities in South Korea
2. Springer will publish Journal of Coastal Conservation
3. Springer book wins Quality of Communication Award
4. Species still have more viable offspring if they can choose their best mate
5. From brains to behavior: Cold Spring Harbor Protocols features methods for neuroscience research
6. Estuarine Research Federation chooses Springer as publishing partner
7. Springer and the New York Botanical Garden Press join forces to publish botanical journals
8. Cold Spring Harbor Protocols highlights a method that captures cell growth and activity
9. Hellish hot springs yield greenhouse gas-eating bug
10. Springer founds new journal Air Quality, Atmosphere and Health
11. Moms obesity during conception phase may set the stage for offsprings obesity risk

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2009)...ave crystallised a protein that may help gut bacte...n could be used by probiotic producers to identify...people. , "Probiotics need to interact with cells...f they attach to surfaces in the gut they are more... activity," says Dr Nathalie Juge from the Institu...
(Date:11/24/2009)...evel action of a remarkable class of ring-shaped p...th the Lawrence Berkeley National Laboratory (Berk...lography beamline at the Advanced Light Source (AL...e expression and replication, and are vital to the...ctious agents, such as the human papillomavirus, w...
(Date:11/24/2009)... NEW YORK (November 24, 2009) -- The Wildlife C... revealing that the last remaining population of S...ue to the rising tide of poaching and habitat loss...form Russian officials of what needs to be done to...est cat. , The report was released ...
Breaking Biology News(10 mins):A sticky solution for identifying effective probiotics 2Atomic-level snapshot catches protein motor in action 2Atomic-level snapshot catches protein motor in action 3Atomic-level snapshot catches protein motor in action 4Report shows dramatic decline in Siberian tigers 2Carbon nanoparticles toxic to adult fruit flies but benign to young 9513 1Carbon nanoparticles toxic to adult fruit flies but benign to young 9513 2Carbon nanoparticles toxic to adult fruit flies but benign to young 9513 3Inverness Medical Innovations to Present at the Canaccord Adams Global Growth Conference on August 11 2009 53945 1Hospice Partners On Call Selects Category 5 Hurricane Rated 1Vault Networks to Safeguard Server and Call Center Infrastructure 53942 1Hospice Partners On Call Selects Category 5 Hurricane Rated 1Vault Networks to Safeguard Server and Call Center Infrastructure 53942 2
...rup and his colleagues from the University of Cope...pebjerg Hospital have followed a soccer team consi... For a period of 3 months, the players have been s...ngs, total mass of muscles, percentage of fat, blo...Surprising results ,- 2-3 weekly rounds of soccer ...
...Chicago have discovered a chemical compound in mal... first time in any species that an entire enzyme s...ex. , The research, performed using nuclear magn...oS ONE, the peer-reviewed, open-access resource fr...one level differences are generally accepted as th...
... World War II, actinide,chemistry has been essenti...sts still seek the ability to interpret and predic...pounds and materials using first principle theory....oal closer to achievement. , PNNL scientist Jun L...utational actinide chemistry at the national meeti...
Other Biology News:Soccer burns more fat than jogging 2Soccer burns more fat than jogging 3First finding of a metabolite in 1 sex only 2
(Date:11/28/2009)... The Vanuatu National Adv...its Second National Communication (SNC) Project in...vices and CLIMsystems Ltd. of New Zealand have gen...se results that will form the background for the c... Framework Convention on Climate Change (UNFCCC). ...
(Date:11/27/2009)..., , PARIS, November 27 /PRNewswire-Fir...approval to market Oralair(R) in both adults and c...rmany, the first country where,Oralair(R) has been... Oralair(R) is now registered in Austria, Belgi... France, Germany, Greece, Hungary, Ireland, Italy,...
(Date:11/26/2009)..., , WEST LAFAYETTE, Ind. - A new generation of u...hips using tiny structures called semiconducting n...ry by researchers at IBM, Purdue University and th... researchers have learned how to create nanowires ...y defined at the atomic level, which is a critical...
(Date:11/25/2009)..., , BOSTON, Nov. 25 ...e H1N1 virus, genomic data from the 1918 pandemic ...the current H1N1 pandemic, today issued its latest...hows that the lethality of the H1N1 ("Swine Flu") ...during the virus,s current outbreak in the spring ...
Breaking Biology Technology:Preliminary Climate and Sea Level Changes for Vanuatu Through the Application of SimCLIM 2Preliminary Climate and Sea Level Changes for Vanuatu Through the Application of SimCLIM 3Preliminary Climate and Sea Level Changes for Vanuatu Through the Application of SimCLIM 4STALLERGENES is Granted a Marketing Authorization for Oralair(R) in Europe 2STALLERGENES is Granted a Marketing Authorization for Oralair(R) in Europe 3Nanowires key to future transistors, electronics 2Nanowires key to future transistors, electronics 3Biological H1N1 Vaccines: Too Little, Too Late 2Biological H1N1 Vaccines: Too Little, Too Late 3Biological H1N1 Vaccines: Too Little, Too Late 4Biological H1N1 Vaccines: Too Little, Too Late 5
... of Group Purchasing Organizations Hosted,by Trane...ociety of,Healthcare Engineering (ASHE) offers pro...- and this years, annual conference is no exceptio..., a leading global supplier of,indoor comfort syst...s from Trane will make two presentations at the 45...
...set, Inc.,(Nasdaq: VRUS ) announced today that it... 14, 2008 with a select group of institutional,inv...k in a "registered,direct" offering. The investors...price of $17.85 per share resulting in gross proce...before deducting placement agent,fees and estimate...
...PRNewswire-FirstCall/ --,China-Biotics, Inc. (OTC ...ny"), a leading Chinese firm specializing in the m...stribution of probiotics products,today announced ... Company,("AST") as its new transfer agent and reg...red in New York, New York, replaces the Company,s ...
Other Biology Technology:Healthcare Facility Managers Learn to Optimize Surgical Suites at 2008 ASHE Annual Conference 2Healthcare Facility Managers Learn to Optimize Surgical Suites at 2008 ASHE Annual Conference 3Pharmasset Announces $25.9 Million Registered Direct Offering of Common Stock 2Pharmasset Announces $25.9 Million Registered Direct Offering of Common Stock 3China-Biotics, Inc. Announces Appointment of New Transfer Agent Effective August 15, 2008 2
...prehensive array of accessories. JULABO water bat...ater protected keypad offer a high operating comfo...o 6 temperature values is visible from across the ...emperature control eliminates temperature overshoo...
Poly-HRP Dilution Buffer from Endogen
... an aqueous solution that contains a purified bovi...ls in a MOPS buffer (3-(N-Morpholino) propanesulfo...ombination of 0.02% methylisothiazolone, 0.02% bro...as Company) as a preservative. StabilZyme HRP Con...
Ribonucleic acid, transfer from baker's yeast (S. cerevisiae) from Sigma-Aldrich
Biology Products: