Navigation Links
Cold Spring Harbor Laboratory's lung cancer research program awarded $100,000 grant
Date:1/10/2008

Cold Spring Harbor, NY Cold Spring Harbor Laboratorys (CSHL) researcher Raffaella Sordella, Ph.D. was awarded $100,000 by Joans Legacy: The Joan Scarangello Foundation to Conquer Lung Cancer. The two-year grant will fund CSHLs pioneering lung cancer research involving a new class of genetic mutations that appear to be a trigger in non-small cell lung cancer, the leading cause of cancer deaths in the United States.

The mutations, called epidermal growth factor receptors (EGFR), are more common in women than in men. This raises the possibility that interactions between EGFR and estrogen might be important in the development of tumors harboring EGFR mutations.

Our research will build upon preliminary observations that estrogen provokes EGFR activity in non-small cell lung cancer, Sordella said. We hypothesize that normal estrogen levels prevent the development of tumors harboring EGFR genetic abnormalities, tumors harboring these genetic lesions may arise when estrogen levels decrease, as is the case with post-menopausal women.

The Joans Legacy grant awarded to Dr. Sordella is part of a $1.2 million grant designated by the Foundation for twelve researchers conducting innovative projects at nationally recognized institutions like Cold Spring Harbor Laboratory. Over the past five years, the Foundation has awarded 36 grants, including those made in collaboration with other research-focused lung cancer nonprofits. A 2005 Joans Legacy grant awarded to CSHL researcher David Mu, Ph.D. enabled his discovery of three new genes that cause lung cancer.

In 2007, we received a record-breaking 65 proposals for funding. This overwhelming response demonstrates how funding availability can stimulate the scientific community to focus efforts on this often neglected disease with its low survival rates, said Joans Legacy President Mary Ann Tighe.

Lung cancer is the number one cancer killer in the United States, taking more than 160,000 lives each year. Yet lung cancer receives less research funding than almost any other cancer, making the work of Joans Legacy even more compelling.


'/>"/>

Contact: Jim Bono
bono@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory
Source:Eurekalert

Related biology news :

1. Springer increases publishing activities in South Korea
2. Springer will publish Journal of Coastal Conservation
3. Springer book wins Quality of Communication Award
4. Species still have more viable offspring if they can choose their best mate
5. From brains to behavior: Cold Spring Harbor Protocols features methods for neuroscience research
6. Estuarine Research Federation chooses Springer as publishing partner
7. Springer and the New York Botanical Garden Press join forces to publish botanical journals
8. Cold Spring Harbor Protocols highlights a method that captures cell growth and activity
9. Hellish hot springs yield greenhouse gas-eating bug
10. Springer founds new journal Air Quality, Atmosphere and Health
11. Moms obesity during conception phase may set the stage for offsprings obesity risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... and BANGALORE, India , April 28, 2016 ... a product subsidiary of Infosys (NYSE: INFY ), ... a global partnership that will provide end customers ... mobile banking and payment services.      (Logo: ... innovation area for financial services, but it also plays a ...
(Date:4/19/2016)... April 20, 2016 The new ... a compact web-based "all-in-one" system solution for all door ... reader or the door interface with integration authorization management ... control systems. The minimal dimensions of the access control ... the building installations offer considerable freedom of design with ...
(Date:4/13/2016)... April 13, 2016  IMPOWER physicians supporting Medicaid patients ... a new clinical standard in telehealth thanks to a ... the higi platform, IMPOWER patients can routinely track key ... body mass index, and, when they opt in, share ... visit to a local retail location at no cost. ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... NC (PRWEB) , ... June 27, 2016 , ... ... just published their findings on what they believe could be a new and ... of the new research. Click here to read it now. , ...
(Date:6/27/2016)... ... June 27, 2016 , ... Newly created 4Sight ... solutions to the healthcare market. The company's primary focus is on new product ... marketing strategies that are necessary to help companies efficiently bring their products to ...
(Date:6/27/2016)... , June 27, 2016  Liquid Biotech ... the funding of a Sponsored Research Agreement with ... tumor cells (CTCs) from cancer patients.  The funding ... CTC levels correlate with clinical outcomes in cancer ... data will then be employed to support the ...
(Date:6/24/2016)... discussions on a range of subjects including policies, debt and ... Poloz. Speaking at a lecture to the Canadian ... to the country,s inflation target, which is set by both ... "In certain areas there needs to be ... why not sit down and address strategy together?" ...
Breaking Biology Technology: