Navigation Links
Cold Spring Harbor Laboratory neuroscientist awarded 'Transformative' NIH research grant
Date:9/30/2010

Cold Spring Harbor, N.Y. Anthony Zador, Ph.D., Professor of Biology and Program Chair in Neuroscience at Cold Spring Harbor Laboratory (CSHL), has been awarded a $2.17 million, 5-year grant by the National Institutes of Health (NIH)'s Transformative Research Projects Program (T-R01). The T-R01 program, supported by the NIH Common Fund (formerly the NIH Roadmap for Medical Research), is a unique research opportunity that encourages researchers to rethink the way science is conducted and propose truly daring ideas.

"Complex research projects, even exceptionally high impact ones, are tough to get funded without the necessary resources to assemble teams and collect preliminary data. The TR01 awards provide a way for these high impact projects to be pursued," said NIH Director Francis S. Collins, M.D., Ph.D. Although these projects are deemed high-risk, they have the potential to create or overturn fundamental paradigms and impact a broad area of biomedicine.

Zador's T-R01 -funded research project is aimed at one of neuroscience's most fundamental, but as-yet-unknown entities: the 'connectome' or the complete wiring diagram of the brain. The brain is an extremely complex network, consisting of billions of neurons interconnected by trillions of synapses or junctions where electrical currents are transmitted. To understand brain function, detailed knowledge of these connectionsquestions such as which neurons connect synaptically with which other neurons, and where in the brain this interaction occursis critical.

"Disruption of this connectivity may cause many neuropsychiatric diseases including autism and schizophrenia, but only a minute fraction of these connections have been mapped to date," explains Zador. "The goal of my project is to develop a novel, high-throughput method to probe the connectivity of neural circuits at the level of individual neurons in mice." This method would allow Zador to analyze a large numbers of these connections in a rapid, economic way.

By compiling such a connectivity atlas in animal models, Zador hopes to determine if and how disruption of connectivity contributes to neuropsychiatric diseases such as mental retardation, autism and schizophrenia.

Zador is the third CSHL scientist to receive a T-R01 grant. His colleagues in the CSHL neuroscience program, Partha Mitra, Ph.D., and Josh Dubnau, Ph.D., received NIH's transformative grants in 2009, when the T-R01 program was launched.

"My congratulations to Tony Zador on receiving this prestigious, highly competitive award," said CSHL President and cancer researcher Bruce Stillman, Ph.D. "His achievement, and that of Drs. Mitra and Dubnau, are a testament to CSHL's passionate commitment to nurture scientists in their pursuit of answers to the most important questions in biomedical research."


'/>"/>

Contact: Hema Bashyam
bashyam@cshl.edu
516-367-6822
Cold Spring Harbor Laboratory
Source:Eurekalert

Related biology news :

1. Rotating high-pressure sodium lamps provide flowering plants for spring markets
2. Springer editor awarded Volvo Environment Prize
3. Nanosprings offer improved performance in biomedicine, electronics
4. Therapeutic Hypothermia journal launching in spring 2011
5. Cold Spring Harbor Protocols features chromosomal rearrangement, gene copy number methods
6. Immune responses during pregnancy linked to schizophrenia among offspring
7. Texas A&M spring graduate contributes to mental retardation research published in Nature
8. Zinc finger nuclease, immunoprecipitation methods featured in Cold Spring Harbor Protocols
9. Exposure to early evening sunlight in spring creates teenage night owls
10. Rapid growth in adolescence leads to fewer offspring, UC Riverside biologists find
11. Springer to publish Journal of NeuroVirology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2016)... -- The Department of Transport Management (DOTM) of ... US Dollar project, for the , Supply and ... and IT Infrastructure , to Decatur ... of Identity Management Solutions. Numerous renowned international vendors participated in ... was selected for the most compliant and innovative solution. ...
(Date:5/20/2016)... MINNEAPOLIS , May 20, 2016  VoiceIt ... technology partnership with VoicePass. By working ... user experience.  Because VoiceIt and VoicePass take slightly ... two engines increases both security and usability. ... expressed excitement about this new partnership. ...
(Date:4/28/2016)... India , April 28, 2016 ... Infosys (NYSE: INFY ), and Samsung SDS, a ... that will provide end customers with a more secure, ... services.      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ) , ... services, but it also plays a fundamental part in enabling ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... 23, 2016 , ... STACS DNA Inc., the sample tracking software company, today ... Laboratory, has joined STACS DNA as a Field Application Specialist. , “I am ... and COO of STACS DNA. “In further expanding our capacity as a scientific integrator, ...
(Date:6/23/2016)... Ky. , June 23, 2016 ... two Phase 1 clinical trials of its complement ... placebo-controlled, single and multiple ascending dose studies designed ... pharmacodynamics (PD) of subcutaneous injection in healthy adult ... subcutaneously (SC) either as a single dose (ranging ...
(Date:6/23/2016)... 23, 2016 Andrew ... http://doi.org/10.17925/OHR.2016.12.01.22 Published recently in ... journal from touchONCOLOGY, Andrew D Zelenetz , ... cancer care is placing an increasing burden on ... biologic therapies. With the patents on many biologics ...
(Date:6/23/2016)... Francisco, CA (PRWEB) , ... June 23, 2016 ... ... (EDC) software, is exhibiting at the Pennsylvania Convention Center and will showcase its ... Annual conference. ClinCapture will also be presenting a scientific poster on Disrupting Clinical ...
Breaking Biology Technology: