Navigation Links
Codeine not safe for all breastfeeding moms and their babies
Date:8/20/2008

Using pain treatments which contain codeine may be risky for some breastfeeding mothers, according to researchers at The University of Western Ontario, and the Hospital for Sick Children (SickKids) in Toronto. Lead author Dr. Gideon Koren published research in the journal, Clinical Pharmacology & Therapeutics which suggests that the codeine used in some pain relief drugs can actually have harmful and even fatal results for infants when ingested by some breastfeeding mothers.

"With nearly half of all infants in North America being delivered by caesarean section or after episiotomy, there is clearly a requirement for pain relief for mothers," says Koren. "However, our study confirms that codeine as a treatment for pain may be unsuitable and cannot be considered safe for all breastfed infants."

Koren holds the Ivey Chair in Molecular Toxicology at the Schulich School of Medicine & Dentistry at The University of Western Ontario, and is a professor of pediatrics at both Western and the University of Toronto. He is also a senior scientist in the Child Health Evaluative Sciences program at SickKids Research Institute, and director of The Motherisk Program.

Codeine is commonly used for pain relief and is recommended by the American Academy of Pediatrics as being compatible with breastfeeding. Following numerous reports through the Motherisk counseling service and the tragic death of an infant who died from an overdose of morphine acquired from breast milk, Koren and his team, located at SickKids and The University of Western Ontario, investigated these negative reactions.

Codeine is a 'prodrug' which means that on its own it is relatively inactive. The pain relieving attributes are only activated when it is metabolized, or transformed by the body into a more active pain relieving compound, morphine. Some individuals have a genetic variance which causes them to metabolize codeine at a rapid rate, producing signific
'/>"/>

Contact: Kathy Wallis
kwallis3@uwo.ca
519-661-2111 x81136
University of Western Ontario
Source:Eurekalert

Page: 1 2

Related biology news :

1. New breastfeeding study shows most moms quit early
2. Early cessation of breastfeeding by HIV+ women in poor countries and child survival
3. Breastfeeding boost IQ in infants with helpful genetic variant
4. Parents shape whether their children learn to eat fruits and vegetables
5. Guilt on their hands: tiny tags could help to solve and deter gun crime
6. Male fish deceive rivals about their top mate choice
7. Syracuse University scientists discover how some bacteria may steal iron from their human hosts
8. Ultrasonic frogs can tune their ears to different frequencies
9. Pregnant mice block out unwelcome admirers to protect their pups
10. Researchers catch ion channels in their opening act
11. Children born after donor insemination should be told as soon as possible about their conception
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/19/2014)... electricity access in India over the last 30 ... carbon emissions growth during that time, according to ... Nature Climate Change ., "Energy access is fundamental ... of life, including education, communication, and health," says ... , While increased energy access is widely agreed ...
(Date:10/18/2014)... a group of 2,000 patients referred for evaluation ... potential molecular diagnosis for 25 percent, including detection ... new mutations contributing to disease, according to a ... is being released to coincide with the American ... sequencing analyzes the exons or coding regions of ...
(Date:10/17/2014)... – Accurate knowledge regarding Ebola is critical and pertinent ... of hazardous global outbreak and epidemic. The Journal, ... a special issue, Ebola Virus and Public Health, to ... knowledge in this critical societal moment. , On ... Ebola for Clinicians . The primer was prepared by ...
Breaking Biology News(10 mins):Improved electricity access has little impact on climate change 2Whole-exome sequencing shows potential as diagnostic tool 2
... 28, 2011) University of Kentucky plant pathologists recently discovered ... the ability of plants, animals, humans and one-celled microorganisms to ... level, which is known as systemic immunity. This mode of ... the key events that stimulate that resistance have remained a ...
... Western Reserve University has detected tiny amounts of Iodine 131 ... campus building. Gerald Matisoff, professor of geology, said ... health. He estimated the level of radiation is about one-tenth ... 131 could have come from any radioactive waste processing facility," ...
... of scientists has discovered that descendants of "exploratory" butterflies ... cautious cousins. The team, led by James Marden, a ... Wheat, a post-doctoral scholar working at both Penn State ... the genetic bases for faster egg maturation, a higher ...
Cached Biology News:Kentucky researchers find a key to plant disease resistance 2Butterfly study reveals traits and genes associated with establishment of new populations 2Butterfly study reveals traits and genes associated with establishment of new populations 3Butterfly study reveals traits and genes associated with establishment of new populations 4
(Date:10/22/2014)... YORK , Oct. 22, 2014 Nuvilex, ... Federation, approximately 400 million people worldwide are living with ... million people by 2030.  The global market for diabetes ... 2012 approximately 330,000 people worldwide died from pancreatic cancer.  ... death due to cancer in the United ...
(Date:10/20/2014)... Mapp Biopharmaceutical,s valiant effort to produce ... fight the Ebola outbreak will make the public ... of pharmaceuticals can be, according to Kalorama Information.  ... some may be taken aback by the three-month ... knowledge are well aware of the complex issues ...
(Date:10/20/2014)... -- , A major pan-European survey into ... of care has revealed changing trends in many important ... provision of healthcare services across the continent. The results ... Gastroenterology (UEG), have been announced today and led to ... burden of GI disorders across Europe ...
(Date:10/20/2014)... October 20, 2014 Earle ... LLC, announced today that Ellen Teplitzky, an experienced ... for the pharmaceutical industry, has joined the firm ... its legal services practice. NDA Partners provides ... witness and testimony, to top law firms and ...
Breaking Biology Technology:Nuvilex Brief Analyst Report: Thinking Outside the Box by BrokerBank Securities, Inc. 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 2Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 5NDA Partners Appoints Ellen Teplitzky, JD as Director of its Legal Services Practice 2
... Standards and Technology (NIST) colored lots of eggs recently. ... smallin fact, too small to see without a microscope. ... strategies for making future low-power computer memories. For ... used electron-beam lithography to make thousands of nickel-iron magnets, ...
... new kind of cloaking material that can render ... this design can,t translate into an invisibility cloak ... in diagnostics, security, and communication. The cloak, ... engineering at Northwestern,s McCormick School of Engineering and ...
... 27, 2011 Talecris Biotherapeutics Holdings Corp. ("Talecris") (NASDAQ: ... for the three months ended March 31, 2011 and ... Exchange Commission (SEC). First quarter 2011 net ... million from $381.0 million in the first quarter of ...
Cached Biology Technology:Good eggs: NIST nanomagnets offer food for thought about computer memories 2Researchers create terahertz invisibility cloak 2Talecris Biotherapeutics Announces First Quarter 2011 Results 2Talecris Biotherapeutics Announces First Quarter 2011 Results 3Talecris Biotherapeutics Announces First Quarter 2011 Results 4Talecris Biotherapeutics Announces First Quarter 2011 Results 5Talecris Biotherapeutics Announces First Quarter 2011 Results 6Talecris Biotherapeutics Announces First Quarter 2011 Results 7Talecris Biotherapeutics Announces First Quarter 2011 Results 8Talecris Biotherapeutics Announces First Quarter 2011 Results 9Talecris Biotherapeutics Announces First Quarter 2011 Results 10Talecris Biotherapeutics Announces First Quarter 2011 Results 11Talecris Biotherapeutics Announces First Quarter 2011 Results 12Talecris Biotherapeutics Announces First Quarter 2011 Results 13Talecris Biotherapeutics Announces First Quarter 2011 Results 14Talecris Biotherapeutics Announces First Quarter 2011 Results 15Talecris Biotherapeutics Announces First Quarter 2011 Results 16
...
... High pH This pH 9.9 solution ... to immunohistochemical staining procedures. It is for ... on glass slides. For particular antigens, target ... effective. It should be noted that also ...
... A very potent Rnase ... effective over a broad range ... This protein does not inhibit ... polymerase, AMV and M-MLV reverse ...
... Dako Target Retrieval Solution, pH 9 (x ... buffer, pH 9, intended for heat-induced target ... is well-suited for use on formalin-fixed, paraffin-embedded ... with 0.01 mol/L citrate buffer, pH 6, ...
Biology Products: