Navigation Links
Co-transplanted cells and treadmill training aids rats with spinal cord injury
Date:11/25/2013

Putnam Valley, NY. (Nov. 25 2013) After Schwann cells (SCs), the principal cells in the peripheral nervous system, and olfactory ensheathing cells (OECs), cells that ensheath the non-myelinated peripheral neurons in the nose, were co-transplanted into laboratory rats with spinal cord injury, researchers in Beijing, China put the rats on a 30 minute per day treadmill training program for ten weeks to determine if the effects of the workouts would benefit aspects of the animals' recovery. The research team, whose results will soon be published in the supplementary International Association of Neurorestoratology (IANR) issue of Cell Transplantation (22(s1)), and are currently freely available on-line as an unedited early e-pub at http://www.ingentaconnect.com/content/cog/ct/pre-prints/content-cog_09636897_ct2455sun, determined that the test animals did gain a synergistic benefit from cell transplantation and exercise that included axonal growth and neuronal plasticity.

The SCs were injected directly into the spinal cord lesion while the OECs were injected into adjacent tissues. Researchers found that when the SCs and OECs were co-injected, they had a combined effect of promoting axonal regeneration and motor functional improvement. However, the treadmill workouts had the effect of improving limb function and neural plasticity.

"After 30 minutes of daily treadmill training over ten weeks, the test animals displayed a significantly improved hind limb function and changes in the distribution and number of tyrosine hydroxylase positive (TH+) neurons in the L2 cord," said study corresponding author Dr. Tiansheng Sun of the Beijing Army General Hospital. "This indicates the important role of plasticity of TH+ interneurons and motoneurons in the L2 spinal cord in functional recovery."

The researchers reported that, consistent with
'/>"/>

Contact: Robert Miranda
cogcomm@aol.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

Page: 1 2

Related biology news :

1. Scientists capture redox moments in living cells
2. How living cells solved a needle in a haystack problem to produce electrical signals
3. In plant photosynthesis, scientists see clues for improving solar energy cells
4. LSUHSC research finds combo of plant nutrients kills breast cancer cells
5. Scientists have been able to grow artificial skin using stem cells from the umbilical cord
6. A study on cell migration provides insights into the movement of cancer cells
7. USF researchers show invasive sparrows immune cells sharpen as they spread
8. Bone marrow mononuclear stem cells show no new gains in heart function says TIME study
9. Salk scientists for the first time generate mini-kidney structures from human stem cells
10. Human stem cells used to elucidate mechanisms of beta-cell failure in diabetes
11. SIGNAL found to enhance survival of new brain cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... the Terra satellite show the different areas that have been ... The burn scars show up as reddish-brown splotches of ... across the remote parts of Eastern Russia in the Sakha ... instrument, it is still possible to see the smoke ... noted below show the devastating number of fires that have ...
(Date:7/25/2014)... of biomedical engineering at the University of Houston, ... and artificial organ development., "Introduction to Tissue Engineering: ... entering into the field of artificial organ development. ... engineering at UH, served as a series editor ... are other published books on the subject of ...
(Date:7/25/2014)... (DTT), which is derived from diffusion tensor imaging ... tracts, such as the corticospinal tract, the rubrospinal ... corticospinal tract is known to be a major ... brain. Several studies have reported on injury of ... some studies have demonstrated recovery of a corticospinal ...
Breaking Biology News(10 mins):University of Houston researcher publishes textbook on tissue engineering 2
... pressure were recently identified in a comprehensive international ... study, in which Uppsala University researchers participated, are ... Nature Genetics . High blood pressure ... Previous studies have shown that it is extremely ...
... May 8 Military and civilian personnel from the ... local homeland security, law enforcement and other first-responder personnel ... been encouraged to register and attend the 2009 Force ... held at Stafford Regional Airport and Marine Corps Base, ...
... and south sides of a house may decrease summertime ... a recent study* of California homes by researchers from ... the U.S. Department of Agriculture (USDA). The first ... the effects of shade on 460 single-family homes in ...
Cached Biology News:Comprehensive genetic study paves way for new blood-pressure medicines 2Demonstration Features Commercial Technology for Combating Terrorism 2New study: Home energy savings are made in the shade 2
(Date:7/24/2014)... , July 24, 2014  ECC West Africa, ... Colorado with University College Hospital (UCH) Ibadan ... development project to finance, design, construct, and operate and ... Nigeria . Under the first of the ... scoping documents and funding applications. UCH Ibadan intends to ...
(Date:7/24/2014)... materialise. Yet, scientists are making progress in devising ... such approach relies on quantum dotsa kind of ... field. A new study demonstrates that changing the ... with electrical impulses can help better control them. ... used as quantum information units, which would produce ...
(Date:7/24/2014)... , July 24, 2014 Research ... "Global Cell Culture Market 2014-2018" report to ... Cell culture is the in vitro growth ... as research, cell studies, and biopharmaceutical production. Cell culture ... production. Cell culture instruments and cell culture consumables are ...
(Date:7/24/2014)... MENLO PARK, Calif. , July 24, 2014 /PRNewswire/ ... million, seven-year contract with the National Institute of Allergy ... of Health, to conduct preclinical development of potential therapies ... development of drugs to treat HIV and AIDS and ... as well as microbicides for preventing sexual transmission of ...
Breaking Biology Technology:ECC Signs a Contract for the Finance, Design, and Construction of a Premier Cancer Institute in Ibadan, Nigeria 2Global Cell Culture Market 2014-2018: Key Vendors are Becton, Dickinson and Co, EMD, GE Healthcare, Lonza Group, Sigma Aldrich and Thermo Fisher Scientific 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 3
... , EAST BRUNSWICK, N.J., Sept. 8 Savient ... abstracts relating to KRYSTEXXA(TM) (pegloticase) development and treatment failure gout will ... in Philadelphia from October 16-21, 2009. The posters will be ... and include: , , , ...
... , CAMBRIDGE, Massachusetts, September 8 ... the global specialty biopharmaceutical company, is,committed to doing everything ... imiglucerase supply shortage. Shire is pleased to be,able to ... previously,anticipated commercial launch world wide. , ...
... , SAN DIEGO, Sept. 8 Biomatrica, Inc., the ... key appointments that will expand the breadth of leadership and commercial ... continued rapid growth in the development and commercialization of products for ... , Martin Latterich, Ph.D., has joined the company ...
Cached Biology Technology:Multiple Abstracts Related to KRYSTEXXA(TM) Development and Treatment Failure Gout to be Presented at the 2009 ACR/ARHP Annual Scientific Meeting 2Multiple Abstracts Related to KRYSTEXXA(TM) Development and Treatment Failure Gout to be Presented at the 2009 ACR/ARHP Annual Scientific Meeting 3Multiple Abstracts Related to KRYSTEXXA(TM) Development and Treatment Failure Gout to be Presented at the 2009 ACR/ARHP Annual Scientific Meeting 4Update on velaglucerase alfa 2Update on velaglucerase alfa 3Biomatrica Makes Several Key Appointments as Part of Continued Growth Plan 2Biomatrica Makes Several Key Appointments as Part of Continued Growth Plan 3Biomatrica Makes Several Key Appointments as Part of Continued Growth Plan 4Biomatrica Makes Several Key Appointments as Part of Continued Growth Plan 5
Moue Serum 8-12 Weeks Old...
... is collected off the clot fasted non-Swiss Albino mice ... Available Anticoagulants: N-02: Citrate N-04: ... Potassium Oxalate N-10: EDTA (Na) ... CPD N-09: K3EDTA N-11: ...
Contains 100 positive controls for effective screening of HDAC inhibitors by fluorometric method....
dynactin 4, mRNA (cDNA clone MGC:3248 IMAGE:3505855), complete cds...
Biology Products: