Navigation Links
Clues to the ageing of tendons unlocked for the first time
Date:8/5/2014

University of Liverpool scientists have examined the mechanisms that cause ageing in the tendons of horses, opening up the possibility of better treatment for humans.

It has been understood for many years that tendons are highly prone to injury and that this likelihood increases as they age. Why this happens, is currently poorly understood

Now, using samples taken from young and old horses, which have similar tendon properties to those of humans, the team of researchers, which also included scientists from Queen Mary University of London, performed a range of tests to profile the types, quantities and proportions of proteins present in the tendon.

They found marked differences in the proteins in young and old horses, as Chair of Musculoskeletal Biology. Professor Peter Clegg explains: "Injured tendons are extremely painful and limiting in humans and we know that this increases as we get older.

"We're now starting to get to the 'why' of this process by showing that the proteins produced by the cells to repair damage alter as we get older."

The findings of this research also showed that certain protein fragments appear in greater quantities in older horses, suggesting that they are released as the tissue is slowly damaged over time.

In contrast, damaged tendons in younger horses were found to contain more of the proteins used in healing than the damaged samples from old horses, suggesting that healing also slows with age.

Professor Clegg said: "This now opens up the possibility of better treatment and prevention strategies to address tendon injuries in both man and veterinary species such as the horse."


'/>"/>

Contact: Jamie Brown
jamie.brown@liverpool.ac.uk
44-151-794-2248
University of Liverpool
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers look to relatives for clues in quest to develop sources of bioenergy
2. Relative reference: Foxtail millet offers clues for assembling the switchgrass genome
3. Higher pain tolerance in athletes may hold clues for pain management
4. Clues to nervous system evolution found in nerve-less sponge
5. Preserved frogs hold clues to deadly pathogen
6. Remote Siberian lake holds clues to Arctic -- and Antarctic -- climate change
7. Highlighting molecular clues to the link between childhood maltreatment and later suicide
8. Hunting for autisms chemical clues
9. Salt cress genome yields new clues to salt tolerance
10. Gecko feet hold clues to creating bandages that stick when wet
11. A mechanism providing clues for research into pancreatic diabetes is described
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2016)... , May 20, 2016  VoiceIt is ... partnership with VoicePass. By working together, ... experience.  Because VoiceIt and VoicePass take slightly different ... engines increases both security and usability. ... excitement about this new partnership. "This ...
(Date:5/3/2016)... , May 3, 2016  Neurotechnology, a ... the MegaMatcher Automated Biometric Identification System (ABIS) ... large-scale multi-biometric projects. MegaMatcher ABIS can process multiple ... using any combination of fingerprint, face or iris ... MegaMatcher SDK and MegaMatcher Accelerator , ...
(Date:4/26/2016)... April 27, 2016 Research ... Multi-modal Biometrics Market 2016-2020"  report to their offering.  ... The analysts forecast the global multimodal ... 15.49% during the period 2016-2020.  Multimodal ... sectors such as the healthcare, BFSI, transportation, automotive, ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... GUELPH, ON , June 27, 2016 /PRNewswire/ - BIOREM ... it has been advised by its major shareholders, Clean ... LP, United States based venture ... common shares of Biorem (on a fully diluted, as ... for the disposition of their entire equity holdings in ...
(Date:6/27/2016)... ... June 27, 2016 , ... ... Amgen, will join the faculty of the University of North Carolina Kenan-Flagler ... of strategy and entrepreneurship at UNC Kenan-Flagler, with a focus on the school’s ...
(Date:6/24/2016)... ... , ... While the majority of commercial spectrophotometers and fluorometers use the z-dimension ... are higher end machines that use the more unconventional z-dimension of 20mm. Z-dimension ... bottom of the cuvette holder. , FireflySci has developed several Agilent flow cell ...
(Date:6/23/2016)... /PRNewswire/ - FACIT has announced the creation of ... company, Propellon Therapeutics Inc. ("Propellon" or "the Company"), ... portfolio of first-in-class WDR5 inhibitors for the treatment ... represent an exciting class of therapies, possessing the ... cancer patients. Substantial advances have been achieved with ...
Breaking Biology Technology: