Navigation Links
Clues to the ageing of tendons unlocked for the first time
Date:8/5/2014

University of Liverpool scientists have examined the mechanisms that cause ageing in the tendons of horses, opening up the possibility of better treatment for humans.

It has been understood for many years that tendons are highly prone to injury and that this likelihood increases as they age. Why this happens, is currently poorly understood

Now, using samples taken from young and old horses, which have similar tendon properties to those of humans, the team of researchers, which also included scientists from Queen Mary University of London, performed a range of tests to profile the types, quantities and proportions of proteins present in the tendon.

They found marked differences in the proteins in young and old horses, as Chair of Musculoskeletal Biology. Professor Peter Clegg explains: "Injured tendons are extremely painful and limiting in humans and we know that this increases as we get older.

"We're now starting to get to the 'why' of this process by showing that the proteins produced by the cells to repair damage alter as we get older."

The findings of this research also showed that certain protein fragments appear in greater quantities in older horses, suggesting that they are released as the tissue is slowly damaged over time.

In contrast, damaged tendons in younger horses were found to contain more of the proteins used in healing than the damaged samples from old horses, suggesting that healing also slows with age.

Professor Clegg said: "This now opens up the possibility of better treatment and prevention strategies to address tendon injuries in both man and veterinary species such as the horse."


'/>"/>

Contact: Jamie Brown
jamie.brown@liverpool.ac.uk
44-151-794-2248
University of Liverpool
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers look to relatives for clues in quest to develop sources of bioenergy
2. Relative reference: Foxtail millet offers clues for assembling the switchgrass genome
3. Higher pain tolerance in athletes may hold clues for pain management
4. Clues to nervous system evolution found in nerve-less sponge
5. Preserved frogs hold clues to deadly pathogen
6. Remote Siberian lake holds clues to Arctic -- and Antarctic -- climate change
7. Highlighting molecular clues to the link between childhood maltreatment and later suicide
8. Hunting for autisms chemical clues
9. Salt cress genome yields new clues to salt tolerance
10. Gecko feet hold clues to creating bandages that stick when wet
11. A mechanism providing clues for research into pancreatic diabetes is described
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... ITHACA, N.Y. , June 23, 2017 ... a leader in dairy research, today announced a new ... help reduce the chances that the global milk supply ... this dairy project, Cornell University has become the newest ... Food Supply Chain, a food safety initiative that includes ...
(Date:5/16/2017)... 16, 2017  Veratad Technologies, LLC ( www.veratad.com ), ... and identity verification solutions, announced today they will participate ... May 15 thru May 17, 2017, in ... Trade Center. Identity impacts the lives ... today,s quickly evolving digital world, defining identity is critical ...
(Date:4/24/2017)... WASHINGTON , April 24, 2017 ... counsel and partner with  Identity Strategy Partners, LLP ... "With or without President Trump,s March 6, ... Foreign Terrorist Entry , refugee vetting can be instilled ... refugee resettlement. (Right now, all refugee applications are ...
Breaking Biology News(10 mins):
(Date:8/23/2017)... ... August 22, 2017 , ... Mettler-Toledo, one of the market leaders ... inspection system . This turnkey system inspects labels, prints, and packaging properties fully automatically, ... different production lines and extended as needed. , The high-end version of the ...
(Date:8/23/2017)... ... 23, 2017 , ... Having proven that its Disruptor™ technology ... company, Green Cell Technologies® (GCT®), has turned its attention to the ... outdated ‘pressing’ methods, ushering in a new era of modern, cost effective and ...
(Date:8/23/2017)... , ... August 23, 2017 , ... ... systems and academic medical centers. The network provides members nationally scaled infrastructure and ... and biologics and restrictive payer agreements so members can provide continuity of care ...
(Date:8/22/2017)... ... 22, 2017 , ... KBioBox is pleased to announce the ... GUIDE-Seq ananlysis. KBioBox has adapted their core technology and direct alignment algorithms to ... to understand reports, extended indel analysis, and translocation analysis. , “The extended GUIDE-Seq ...
Breaking Biology Technology: