Navigation Links
Clues to the ageing of tendons unlocked for the first time
Date:8/5/2014

University of Liverpool scientists have examined the mechanisms that cause ageing in the tendons of horses, opening up the possibility of better treatment for humans.

It has been understood for many years that tendons are highly prone to injury and that this likelihood increases as they age. Why this happens, is currently poorly understood

Now, using samples taken from young and old horses, which have similar tendon properties to those of humans, the team of researchers, which also included scientists from Queen Mary University of London, performed a range of tests to profile the types, quantities and proportions of proteins present in the tendon.

They found marked differences in the proteins in young and old horses, as Chair of Musculoskeletal Biology. Professor Peter Clegg explains: "Injured tendons are extremely painful and limiting in humans and we know that this increases as we get older.

"We're now starting to get to the 'why' of this process by showing that the proteins produced by the cells to repair damage alter as we get older."

The findings of this research also showed that certain protein fragments appear in greater quantities in older horses, suggesting that they are released as the tissue is slowly damaged over time.

In contrast, damaged tendons in younger horses were found to contain more of the proteins used in healing than the damaged samples from old horses, suggesting that healing also slows with age.

Professor Clegg said: "This now opens up the possibility of better treatment and prevention strategies to address tendon injuries in both man and veterinary species such as the horse."


'/>"/>

Contact: Jamie Brown
jamie.brown@liverpool.ac.uk
44-151-794-2248
University of Liverpool
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers look to relatives for clues in quest to develop sources of bioenergy
2. Relative reference: Foxtail millet offers clues for assembling the switchgrass genome
3. Higher pain tolerance in athletes may hold clues for pain management
4. Clues to nervous system evolution found in nerve-less sponge
5. Preserved frogs hold clues to deadly pathogen
6. Remote Siberian lake holds clues to Arctic -- and Antarctic -- climate change
7. Highlighting molecular clues to the link between childhood maltreatment and later suicide
8. Hunting for autisms chemical clues
9. Salt cress genome yields new clues to salt tolerance
10. Gecko feet hold clues to creating bandages that stick when wet
11. A mechanism providing clues for research into pancreatic diabetes is described
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2017)... -- RAM Group , Singaporean based technology ... biometric authentication based on a novel  quantum-state ... perform biometric authentication. These new sensors are based on a ... Group and its partners. This sensor will have widespread ... security. Ram Group is a next generation sensor ...
(Date:4/17/2017)... MELBOURNE, Florida , April 17, 2017 ... security technology company, announces the filing of its 2016 Annual Report ... Securities and Exchange Commission. ... Report on Form 10-K is available in the Investor Relations section ... well as on the SEC,s website at http://www.sec.gov . ...
(Date:4/11/2017)... Research and Markets has announced the addition of the "Global ... ... at a CAGR of 30.37% during the period 2017-2021. ... based on an in-depth market analysis with inputs from industry experts. ... the coming years. The report also includes a discussion of the ...
Breaking Biology News(10 mins):
(Date:6/22/2017)... ... June 22, 2017 , ... Charm Sciences, Inc. is pleased to ... was determined to be appropriate as a screening test at dairies and farms for ... EZ system, and the Charm EZ Lite system. These systems are a combination incubator ...
(Date:6/20/2017)... , ... June 20, 2017 , ... ... immediately determine the adulterants which pose the most likely threat to their products ... of this year. , IFT's annual food expo attracts over 20,000 attendees ...
(Date:6/20/2017)... (PRWEB) , ... June 20, 2017 , ... Do More ... the transition from being a trusted supplier in the weighing industry, to extending its ... extractions, ELISA essays, enzyme reactions, immunoassays, hybridizations and more, allowing for its customers ...
(Date:6/19/2017)... NJ (PRWEB) , ... June 19, 2017 , ... ... innovative solutions for clinical development reported today that it is launching two new ... The company will be demonstrating new capabilities at the DIA 2017 Annual Meeting ...
Breaking Biology Technology: