Navigation Links
Clues to chromosome crossovers
Date:2/13/2013

Neil Hunter's laboratory in the UC Davis College of Biological Sciences has placed another piece in the puzzle of how sexual reproduction shuffles genes while making sure sperm and eggs get the right number of chromosomes.

The basis of sexual reproduction is that a fertilized egg gets half its chromosomes from each parent sperm and eggs each contributing one partner in each pair of chromosomes. We humans have 23 pairs of 46 chromosomes: so our sperm or eggs have 23 chromosomes each.

Before we get to the sex part, though, those sperm and eggs have to be formed from regular body cells that contain twice as many chromosomes. That happens through a specialized type of cell division, meiosis.

During meiosis, the couples in each pair of chromosomes have to, well, couple by "crossing over" with each other. Each chromosome pair must become connected by at least one crossover so that when the couples separate, they are delivered to separate sperm or egg cells.

These crossovers also mean that chromosomes can exchange chunks of DNA with each other, shuffling the genetic deck for the next generation. But if too few crossovers are formed, gametes end up with the wrong number for chromosomes, a situation that can cause infertility, pregnancy miscarriage or chromosomal diseases such as Down Syndrome.

Large-scale studies of human genetics have shown that the number of crossovers formed during meiosis is under genetic control. Moreover, women that make more crossovers tend to have more children. One gene suggested to control crossover numbers in humans, called Rnf212, is the subject of a new study by UC Davis researchers lead by Professor Neil Hunter.

Hunter studies how crossovers form and chromosomes separate at the UC Davis Department of Microbiology & Molecular Genetics and the Comprehensive Cancer Center. In 2009, he was awarded an early career fellowship from the Howard Hughes Medical Institute.

Chromosome p
'/>"/>

Contact: Andy Fell
ahfell@ucdavis.edu
530-752-4533
University of California - Davis
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Researchers look to relatives for clues in quest to develop sources of bioenergy
2. Relative reference: Foxtail millet offers clues for assembling the switchgrass genome
3. Higher pain tolerance in athletes may hold clues for pain management
4. Clues to nervous system evolution found in nerve-less sponge
5. Preserved frogs hold clues to deadly pathogen
6. Remote Siberian lake holds clues to Arctic -- and Antarctic -- climate change
7. Highlighting molecular clues to the link between childhood maltreatment and later suicide
8. Hunting for autisms chemical clues
9. Salt cress genome yields new clues to salt tolerance
10. Gecko feet hold clues to creating bandages that stick when wet
11. A mechanism providing clues for research into pancreatic diabetes is described
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Clues to chromosome crossovers
(Date:1/22/2015)... , Jan. 22, 2015 Research and Markets ... of the "Global Wearable Technologies Market and ... Overview, Trends and Forecast 2014-2020" report to ... are smart devices that can be worn on ...
(Date:1/22/2015)... CHARLOTTE, N.C. , Jan. 22, 2015 Infinisource has ... introduction of the G2 model. The G2 sets a higher ... company,s iSolved human capital management solution. With plug-and-play installation, touch ... G2 time clock provides a robust time collection solution for ...
(Date:12/22/2014)... 2014  NXT-ID, Inc. (NASDAQ: NXTD and NXTDW) ... the growing mobile commerce market, announces it has retained famous ... the 2015 International CES debut of the Wocket™ biometric smart ... at the NXT-ID booth January 6th and 7 th , ...
Breaking Biology News(10 mins):Global Wearable Technologies Market and Applications, Opportunities, Industry Analysis, Segmentation, Size, Growth, Share, Overview, Trends and Forecast 2014-2020 2Infinisource's NXG series sets new time clock standard 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4
... Biophysical Society is pleased to announce that it will ... with the International Biophysics Congress in Long Beach, California, ... talks and poster sessions that take place during the ... to discuss current policy issues facing our nation. The ...
... New research at the University of Chicago finds evidence ... the pain of loneliness: They create people in their ... not a very efficient way to alleviate ones loneliness, ... to do so, said Nicholas Epley, Assistant Professor of ...
... This release is also available in French . ... to community involvement today with a $1-million donation to ... and Hospital (MNI), affiliated with McGill University and the ... $40-million initiative to invest in people and expand facilities ...
Cached Biology News:Biophysical Society to host discussions on the teaching of evolution and on the energy crisis 2People not always needed to alleviate loneliness 2People not always needed to alleviate loneliness 3Building the future -- 21st century nano tools to repair the nervous system 2
(Date:1/23/2015)... Portal Solutions , a technology consulting ... Microsoft Office 365 and SharePoint platforms , today announces its ... being one of the region’s fastest-growing mid-sized companies based on ... , “To be recognized a second year in a row ...
(Date:1/22/2015)... 22, 2015 Shimadzu Scientific Instruments ... multipurpose UV-visible spectrophotometer. Offering wavelength scanning from 190 ... ideal for applications in a variety of industries, ... The user-friendly UV-1280 enables intuitive operation, while the ...
(Date:1/22/2015)... NH (PRWEB) January 22, 2015 GEA ... a table top laboratory homogenizer, the PandaPLUS 2000, which ... nanodispersions, nanoemulsions , and cell disruption . This ... dairy products, fruit juices, liquid food, food additives and ...
(Date:1/22/2015)... Mass (PRWEB) January 21, 2015 Cambridge Semantics, ... Web technology, today announced that 2014 was a record-breaking year ... the capabilities of the Anzo Smart Data Platform and our ... and utilize insights from diverse data which led to record ...
Breaking Biology Technology:Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 2Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 3Shimadzu’s New Monitored Single-Beam UV-Vis Spectrophotometer Offers Comprehensive Measurement Options in a Compact Body 2GEA Niro Soavi Announces the PandaPLUS 2000 Homogenizer for Processing New Applications for Nanoemulsions and Cell Disruption 2Cambridge Semantics Announces Record Results for 2014 2
... U.S. Biogeneric Agents to Reach $2 Billion in Sales by 2016, ... New ... Resources, Inc., one,of the world,s leading research and advisory firms for ... with biologic sales of more than $14 billion in 2006, and ...
... States Boyden Global Executive Search ,Helps Businesses Find the ... ... Boyden Global Executive Search of,Summit is featured in the September ... of the New Jersey Business and,Industry Association (NJBIA), the largest state ...
... N.C., Sept. 5 A study in ... the use of the GlycoMark,1,5-anhydroglucitol (1,5-AG) blood ... especially to target postprandial hyperglycemia (elevated,after-meal glucose ... achieving optimal glycemic control and reducing the ...
Cached Biology Technology:Amgen and Genentech Brace Themselves for Heavy Pressure From Biogenerics Manufacturers 2Boyden's Summit Practice Featured in the September Issue of New Jersey Business Magazine 2Study Supports Use of GlycoMark Blood Test to Evaluate Therapy in Children with Diabetes 2
... of mouse embryonic stem cells to dopaminergic ... midbrain, where they are mainly located in ... and the retrorubral field. These dopaminergic (DA) ... innervation ( e.g.projections to the caudate nucleus, ...
... Microarrays designed for RNA aptamer screening and ... and powerful Paraflo microfluidic on-chip synthesis platform. ... be synthesized on-chip and LC Sciences can ... microarrays are available as part of our ...
... PEP-005 is a synthetic peptide whose sequence is from the C-terminal ... amino acid sequence extends from amino acids 429 to 448 of RAR*. ... P - S - V - S - P - S - ... V - S - Q - S - P - L - ...
... fast and versatile automated strip washer which ... 16-channel manifold. This breakthrough design allows for ... manifolds for overfill washing and overflow protection ... problem of fitting dispense and aspirate tubes ...
Biology Products: