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Clinical trial tests rice bran to prevent cancer
Date:12/5/2012

ment activity includes mediating chronic inflammation that provides a ripe landscape for cancer. Ryan and colleagues including Tiffany Weir, PhD, and Rajesh Agarwal, PhD, are collaborating to evaluate how rice bran may also help to promote an anti-cancer immune response and modulate gut microbiota metabolism for protection against cancer.

"There are well over 100,000 varieties of rice in the world, many with their own unique mix of bioactive components and so one major challenge is to discover the optimal composition for chemoprevention. Another challenge is ensuring that people consistently receive the required daily intake amount or 'dose' needed to demonstrate these chemo-protective effects. That said, rice is an accessible, low-cost food in most places of the world, and so work with rice bran as a dietary chemopreventive agent has the potential to impact a significant portion of the world's population," Ryan says.

Ryan has taken the next step in the evolution of rice bran from diet to prescription, in the form of an ongoing clinical trial testing its chemopreventive effectiveness in a population of colon cancer survivors.


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Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver
Source:Eurekalert

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