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Clinical study suggests estrogen levels and breast health can be altered
Date:4/11/2011

WASHINGTON, D.C April 11, 2011 Researchers from Canada and the United States today told attendees of the Experimental Biology 2011 Scientific Meeting that they have uncovered a possible means of enabling women to favorably influence whether the estrogens in their bodies take a "beneficial path" or a "disease-potential" path.

The researchers tested a nutritional combination of indole-3 carbinol, milk thistle extract, calcium-D-glucarate, Schizandra chinensis fruit extract, stinging nettle, lignans extracted from the Norway spruce, and vitamin D (a combination available as femMED Breast Health, http://www.femmed.com/ ) on 47 pre-menopausal women and 49 post-menopausal women for 28 days. On day one and 28, they analyzed blood and urine samples. Researchers were pleasantly surprised to discover consumption of the femMED supplement significantly increased the mean urinary concentration of 2-OHE in pre- and post-menopausal women (by 110% and 88%, respectively), suggesting a risk-reducing effect. The Breast Health supplement was well-tolerated, and displayed no adverse side effects.

Dr. Cathleen London, MD said, "Although the trial was small it was well designed and well conducted. Importantly, we know that cruciferous vegetables, fish oil, and lignans from flax and nuts are all thought to support healthy metabolism of estrogens, but people do not eat enough fresh cruciferous vegetables in their diet, making nutritional supplementation a viable option. Although this is a preliminary study, it adds to our scientific knowledge about the role of estrogens and their metabolism in the breast health of pre-menopausal and post-menopausal women." Dr. London was not involved with this project.

Maggie Laidlaw, PhD, the lead investigator, said, "While additional studies are necessary, the results of this clinical trial in a relevant population of women show promise that there may be a proactive way to support hea
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Contact: Jeff Nedelman
jeffnedelman@charter.net
703-628-6011
Strategic Communications
Source:Eurekalert

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