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Clearing cells to prevent cervical cancer
Date:7/25/2014

asizes that eliminating SCJ cells does not prevent cervical intraepithelial neoplasias nor does it prevent human papilloma virus (HPV) infectionwhich can lead to cervical cancer. But what is significant about the findings, according to the researchers, is that removal of SCJ cells seems to alter recurrence patterns, presumably by removing the population that is most vulnerable to development of the more dangerous precancers.

"This is a concept that is in great need of a controlled clinical trial aimed at prevention rather than treatment," said Crum. "It would give us important insights into whether preemptive removal of the SCJ region would have the desired effect."

An accompanying editorial, by Silvia Franceschi, MD, International Agency for Research on Cancer, suggests continuation of the work by "careful evaluation of the impact of prophylactic ablation in the framework of large screening programmes."


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Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-6383
Brigham and Women's Hospital
Source:Eurekalert

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