Navigation Links
Clearing cells to prevent cervical cancer
Date:7/25/2014

Boston, MA A study published online in the International Journal of Cancer earlier this month describes a novel approach to preventing cervical cancer based on findings showing successful reduction in the risk of cervical cancer after removal of a discrete population of cells in the cervix.

The findings come from a study that looked at squamocolumnar junction cells, or SCJ cells. These cells reside in the cervical canal and have been implicated as the origins of cervical cancer. A research team co-led by Christopher Crum, MD, director, Brigham and Women's Hospital (BWH) Women's and Perinatal Pathology, demonstrated that removal of SCJ cells resulted in a markedly lower risk of cervical intraepithelial neoplasiaa non-cancerous, abnormal growth of cells on the surface of the cervix that may progress to cervical cancer.

One hundred and thirty-one women with cervical intraepithelial neoplasia were treated with a loop electrosurgical excision procedure to remove the SCJ cells. During the follow-up period (of up to four years), 16 recurrences were identified. Four were identified at the first follow-up visit, and determined to be residual disease, meaning they were not removed in the initial procedure. Twelve manifested after the first postoperative visit and all were in the ectocervix or in mature metaplastic epithelium. All of the 12 delayed recurrences were cervical intraepithelial neoplasias and did not have SCJ cells.

"We have always suspected that most recurrences following apparently successful therapy do not develop in the same location as the original precancer, which was at the squamocolumnar junction," said Crum. "Moreover, studies in the literature have shown that the risk of a significant precancer following successful removal is quite low. Our study is in sync with these observations and suggests that removing SCJ cells might have a significant impact in reducing the risk of cervical cancer."

Crum emph
'/>"/>

Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-6383
Brigham and Women's Hospital
Source:Eurekalert

Page: 1 2

Related biology news :

1. Whitehead Institute researchers create naïve pluripotent human embryonic stem cells
2. Four billion-year-old chemistry in cells today
3. Experiments prove stemness of individual immune memory cells
4. Somatosensory stimulation inhibits excitability of pyramidal cells in rat hippocampal CA1
5. Novel methods may help stem cells survive transplantation into damaged tissues
6. Stem cells aid muscle repair and strengthening after resistance exercise
7. Interleukin-10 aids survival of cells transplanted to repair cardiac tissues after MI
8. Measuring the number of protein molecules inside cells
9. Discovery may make it easier to develop life-saving stem cells
10. CNIO researchers discover a gene that links stem cells, aging and cancer
11. Transplantation of new brain cells reverses memory loss in Alzheimers disease model
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2015)... 2015 This report provides market analysis of ... years. It contains an analysis of the drivers, challenges, ... impact from the short, medium, and long term perspective ... market, and technology trends that currently, prevail in the ... authorities to efficiently manage the increasing marine traffic and ...
(Date:6/23/2015)... DUBLIN , June 22, 2015 ... has announced the addition of the "Body-Worn ... Share, Growth, Trends and Forecast 2014 - 2020" ... report offers strategic analysis of the global body-worn ... market has been segmented on the basis of ...
(Date:6/17/2015)... GERMANTOWN, Maryland , June 17, 2015 ...   Produktlinie mit DNA-Tests verbessert den Analyseprozess und ... QGEN ; Frankfurt Prime Standard: QIA) hat heute in ... Produktlinie Investigator ® für ... Die neuen Kits zur Erstellung genetischer Fingerabdrücke bieten eine ...
Breaking Biology News(10 mins):Automatic Identification System Market by Class, by Platform, by Application and by Geography - Global Forecasts & Analysis to 2014 - 2020 2Body-Worn Temperature Sensors Market - Global Industry Analysis 2QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 2QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 3QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 4QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 5QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 6
... understand how signalling proteins recognize and transport to certain ... insight on the mechanism of major cellular processes such ... be used in the future to understand and cure ... Dimitrios Stamou, Nano-Science Center and Department of Neuroscience and ...
... and becomes food for an entire ecosystem. Researchers at the ... feed only on dead whales - and use DNA technology ... be higher than previously thought. Dead whales constitute an ... and where a whale is going to die, and when ...
... 21, 2009) -- Rice University biochemists are developing a ... of antibiotic resistance. "Our goal is to show ... modify to become drug-resistant," said Yousif Shamoo, the principal ... National Institute of Allergy and Infectious Diseases. "If they ...
Cached Biology News:Nanoresearchers challenge dogma in protein transportation in cells 2New species discovered on whale skeletons 2'Evolutionary forecasting' for drug resistance 2'Evolutionary forecasting' for drug resistance 3
(Date:7/1/2015)... and BANGALORE, India , July ... profiling company that uses next generation sequencing technology to ... Scott A. Storrer as chief executive officer. In ... will be responsible for all strategy, business expansion and ... who has served as Strand,s chairman and CEO since ...
(Date:7/1/2015)... July 1, 2015  Axovant Sciences Ltd. (NYSE: ... the treatment of dementia, today announced that the ... 22 at 5:45 p.m. EDT following its presentation ... International Conference 2015 (AAIC). The ... , Dr. Lawrence Friedhoff , Chief Development ...
(Date:7/1/2015)... ... July 01, 2015 , ... A newly launched business ... to lower the barriers to innovation in life sciences R&D. The Pistoia Alliance President’s ... cash prizes of US$15,000 and a period of expert mentorship from a senior industry ...
(Date:7/1/2015)... ... July 01, 2015 , ... Apex Therapeutics announced today ... Convention in Philadelphia, PA. , The presentation took place on Tuesday, June ... plans for the development of APX3330 for the treatment of pancreatic cancer. A ...
Breaking Biology Technology:Strand Life Sciences Names Scott A. Storrer CEO as Company Continues Global Expansion with Focus on Precision Medicine Product 2Strand Life Sciences Names Scott A. Storrer CEO as Company Continues Global Expansion with Focus on Precision Medicine Product 3Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 2Axovant Sciences To Host Investor Briefing And Live Webcast During AAIC 2015 Meeting 3Pistoia Alliance Launches Startup Challenge 2Pistoia Alliance Launches Startup Challenge 3Apex Therapeutics Presented Company Overview at This Year’s BIO International Convention in Philadelphia, PA 2
... -- Children's Hospital and Health System ... the Eclipsys Sunrise Clinical Manager advanced clinical information ... to Eclypsis Corp, of Boca Raton, ... ED Manager, Pharmacy Benefits Manager, Sunrise Secure Health ...
... - The two-year state budget signed into law Monday ... of many Wisconsin technology firms by changing how corporate ... Wisconsin Technology Council. , ,With bipartisan support ... the "single-sales factor" sales apportionment for corporate income to ...
... - The average citizen may think Gov. Jim Doyle and ... step into the boxing ring of politics. And judging by ... the Capitol over the past two and a half years, ... entirely correct, however, as evidenced by some important tax changes ...
Cached Biology Technology:`Single-sales factor' extends tax treatment to tech, service firms 2`Single-sales factor' extends tax treatment to tech, service firms 3State tax compromises prove that partisanship can be set aside for a while 2State tax compromises prove that partisanship can be set aside for a while 3
Mouse monoclonal antibody raised against a partial recombinant ZNF167. NCBI Entrez Gene ID = ZNF167...
... antibody raised against a partial ... Immunogen: SLC22A3 (NP_068812, 90 ... recombinant protein with GST tag. ... NM_021977 ...
...
... Deletion Cosmid Cloning Kit enables you to ... and unbiased primary cosmid library of genomic ... deletion sublibraries. High efficiency cosmid library construction ... kit protocols. First, genomic DNA is randomly ...
Biology Products: