Navigation Links
Class of antibiotics can enhance gene-silencing tool
Date:7/20/2008

ell called the RNA-induced silencing complex or RISC.

To probe how RISC works, Jin and his co-workers inserted a gene for a fluorescent protein into a cell line, and then added a short piece of RNA that incompletely silences the inserted gene. That way, if a potential drug tweaked the silencing process, the researchers could see it quickly.

They found that enoxacin can increase how well a gene is silenced by up to a factor of ten in cultured cells and by a factor of three in mice. It appears to strengthen the grip of part of RISC, a protein called TRBP, upon small pieces of RNA.


'/>"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University
Source:Eurekalert

Page: 1 2

Related biology news :

1. World-class environment vision to bring back the species
2. bioMETRX, Inc. Garage Door Opener Named Best In Class
3. Compound has potential for new class of AIDS drugs
4. Cold Spring Harbor Protocols features classic approaches for analyzing chromosomes
5. Nobel laureate Dr. Linda Buck elected to American Academy of Arts & Sciences 2008 Class of Fellows
6. New computer applications allow to classify Iberian pig meat automatically
7. New edition of a classic molecular biology textbook from CSHL Press and Benjamin Cummings
8. World class in Systems Biology is the aim
9. Identification of a novel class of (not-so) small RNAs
10. New class of drug offers hope to treatment-resistant AIDS patients
11. Freshman class sparks start-up company
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/18/2014)... In a sample of patients with undiagnosed, suspected genetic ... associated with a higher molecular diagnostic yield than traditional ... JAMA . The study is being released to ... meeting. , Exome sequencing, which sequences the protein­coding region ... genetic material present in a cell or organism), has ...
(Date:10/17/2014)... . Why do ... to reproduce? And why are there two sexes anyway? These ... of the research journal Molecular Human Reproduction published ... Bielefeld University Bielefeld has compiled this special issue on sperm ... to copulate with several males in quick succession – chimpanzees ...
(Date:10/17/2014)... available in German . ... few drugs. When treating overdoses, doctors are often limited to ... if there is a combination of drugs involved. So what ... swallows his grandmother,s pills? ETH professor Jean-Christophe Leroux from the ... an answer to this question. "The task was to develop ...
Breaking Biology News(10 mins):Study examines type of exome sequencing and molecular diagnostic yield 2Study examines type of exome sequencing and molecular diagnostic yield 3Sperm wars 2Emergency aid for overdoses 2Emergency aid for overdoses 3
... (Santa Barbara, Calif.) Viruses fill the ocean ... marine microbiology, according to a professor of biology at ... Carlson, professor with UCSB,s Department of Ecology, Evolution, and ... of marine viruses published this week by the ...
... transport system inside living cells is a well-oiled machine with ... around the cell. These molecular motors are responsible for a ... on the go. They can put themselves into "energy save ... what gets moved around the cell, and when. ...
... is available in Spanish . A ... what is causing the decline in bumble bee populations and ... the next generation of greenhouse pollinators. Bumble bees, like ... used to pollinate greenhouse crops like peppers and tomatoes. But ...
Cached Biology News:Decade-long study reveals recurring patterns of viruses in the open ocean 2Decade-long study reveals recurring patterns of viruses in the open ocean 3Carnegie Mellon scientists discover how molecular motors go into 'energy save mode' 2Carnegie Mellon scientists discover how molecular motors go into 'energy save mode' 3The flight of the bumble bee: Why are they disappearing? 2
(Date:10/22/2014)... Columbia, Md. (PRWEB) October 21, 2014 ... package, an LC/MS/MS data tool for the pain management ... efficiency of data processing and review by allowing users ... importance to clinicians. , QuantAnalytics allows analysts to ... orders. This expedites data processing by eliminating the need ...
(Date:10/22/2014)... Ras Al Khaimah, UAE (PRWEB) October 22, 2014 ... in game-changing life science and healthcare projects, announces the ... MBBS MRCGP DRCOG DCH to its advisory team. Dr. ... research advisory team. , A graduate of ... Dr. Siddiqui was subsequently degreed in medicine in 2001. ...
(Date:10/22/2014)... Oct. 22, 2014 /PRNewswire/ - iCo Therapeutics ("iCo" or ... next steps for its Oral Amphotericin B program.  ... in vitro work involving samples from ... plans to complete pre clinical studies and regulatory ... 1A clinical trial, utilizing approximately $700,000 of funding ...
(Date:10/20/2014)... The report “Pharmacy Automation Systems ... and Labeling Systems, Table-top Counters) by End-user (Inpatient ... & Trends to 2019” analyzes and studies the ... America, Europe, Asia-Pacific, and the Rest of the ... 30 figures spread through 300 pages and in-depth ...
Breaking Biology Technology:Shimadzu Releases QuantAnalytics Open Access LCMS Software Package for Clinical Applications 2Dr. Yousef Siddiqui joins the Grace Century Advisory Team 2iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 2iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 3Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 2Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 3Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 4
... Another Key Regulatory MilestoneLONDON, March 10 Monsanto,s historic ... and biotechnology has contributed to a 24 percent compound ... segment since 2001. This is one of the ... Commercial, will tell investors today as part of a ...
... has long been known for its world-record-breaking carbon ... have discovered new uses by spinning carbon nanotubes ... , Breakthroughs Without Broken Threads ... to grow carbon nanotubes of world-record breaking lengths, ...
... American Pacific Corporation (Nasdaq: APFC ) is ... Chemicals LLC (AFC), located near Sacramento California, recently inaugurated ... The new facility can accommodate either batch reactors (20 ... using up to 7 reactors from 0.25 to 1 ...
Cached Biology Technology:Monsanto's Historic R&D Investment has Contributed to Mid-20s Gross Profit Growth for Its Seeds and Genomics Segment 2Monsanto's Historic R&D Investment has Contributed to Mid-20s Gross Profit Growth for Its Seeds and Genomics Segment 3Spinning carbon nanotubes spawns new wireless applications 2AMPAC Fine Chemicals Announces the Inauguration of the New cGMP Continuous Processing Development Facility 2
... is an evolutionarily conserved form of cell ... The central component of this process ... caspases. These enzymes participate in a ... response to pro-apoptotic signals and result in ...
... is manufactured for DNA purification from agarose ... UV light. The Purification of DNA from ... DNA-cloning work. The conventional method of visualizing ... UV light damages DNA and significantly decreases ...
...
CleanBox DNA workstation with two 254nm UV lambs & 12-hr timer, 90cm (36-inch)width, single door, 115V (w/crating)...
Biology Products: