Navigation Links
Circumcision alters penis microbiome, could explain HIV protection
Date:4/15/2013

Circumcision drastically alters the microbiome of the penis, changes that could explain why circumcision offers protection against HIV and other viral infections. In a study to be published on April 16 in mBio, the online open-access journal of the American Society for Microbiology, researchers studied the effects of adult male circumcision on the types of bacteria that live under the foreskin before and after circumcision. By one year post-procedure, the total bacterial load in that area had dropped significantly and the prevalence of anaerobic bacteria, which thrive in locations with limited oxygen, declined while the numbers of some aerobic bacteria increased slightly.

"The change in the communities is really characterized by the loss of anaerobes. It's dramatic," says the corresponding author, Lance Price of the Translational Genomics Research Institute (TGen) in Flagstaff, Arizona and George Washington University in Washington, DC. "From an ecological perspective, it's like rolling back a rock and seeing the ecosystem change. You remove the foreskin and you're increasing the amount of oxygen, decreasing the moisture - we're changing the ecosystem," he continues.

Randomized controlled trials show that circumcision reduces the risk of HIV infection in men by 50-60% and reduces the risk of infection with human papillomavirus and herpes simplex virus type 2, but the biology behind these benefits is not well understood. It could be that the anatomy of the circumcised penis helps prevent infection, or it could be that changes in the microbiome confer protection, or some combination of the two.

Using swab samples from a large circumcision trial in Uganda, Price and his colleagues at Johns Hopkins and TGen set out to determine whether circumcision significantly alters the penis microbial community. Using a quantitative technique called qPCR along with pyrosequencing to identify individual community members, the researchers compa
'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Gastric bypass surgery alters gut microbiota profile along the intestine
2. Acute stress alters control of gene activity
3. Intense prep for law school admission test alters brain structure
4. New approach alters malaria maps
5. Heart-powered pacemaker could one day eliminate battery-replacement surgery
6. New test could help track down and prosecute terrorists
7. New antibiotic could make food safer and cows healthier
8. BPA could affect reproductive capabilities, cause infection of the uterus
9. Key to immune system disease could lie inside the cheek
10. New analysis of premature infants heartbeats, breathing could be cues for leaving NICU
11. Tiny electrical sensors could signal faster MRSA diagnosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2015)... , March 24, 2015   NexID Biometrics ... with critical security-authentication needs, today announced the beginning of ... (FFD) solution. The company, based in ... at the three-day Connect:ID Expo, which began here today ... NexID said version 2.0 of its SDK boosts the ...
(Date:3/23/2015)... March 23, 2015  In the 2014 fiscal year, ... conviction losses. This figure accounts for a fraction of ... The Nilson Report, exceeds $11 billion globally. The polygraph ... a crime has occurred. Investor Mark Saint Juste ... Joe Paolella partnered to administer the test ...
(Date:3/20/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... the growing mobile commerce market, announces its biometric payment ... products featured in 2015 "I Want That" International CES ... on the DIY Network.   DIY,s "I ... , site of the 2015 International CES for a ...
Breaking Biology News(10 mins):NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 2NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 3
... the University of Illinois have developed a new model ... transform the understanding of how plants and soils interact ... model takes into account the role of nitrogen dynamics ... change and rising atmospheric carbon dioxide. Current models ...
... (Dec. 11, 2007) A new study comparing the ... actual climate data finds that the models do an ... of the atmosphere. This research, published on-line Wednesday ... raises new concerns about the reliability of models used ...
... climate negotiations proceed in Bali, Indonesia, researchers have taken ... different countries to future climate change. The research ... Centre for Theoretical Physics in Trieste, Italy, found that ... gas-emitting nations that are currently unbound by the Kyoto ...
Cached Biology News:New model revises estimates of terrestrial carbon dioxide uptake 2New model revises estimates of terrestrial carbon dioxide uptake 3New study increases concerns about climate model reliability 2New study increases concerns about climate model reliability 3Scientists develop new measure of 'socioclimactic' risk 2Scientists develop new measure of 'socioclimactic' risk 3Scientists develop new measure of 'socioclimactic' risk 4
(Date:5/4/2015)... May 4, 2015  Soligenix, Inc. (OTCQB: SNGX) (Soligenix ... that address unmet medical needs in the areas of ... be presenting preclinical data from three of its biodefense ... and Technology Conference on May 12-14, 2015 to be ... Convention Plaza, St. Louis MO ...
(Date:5/4/2015)... WASHINGTON , May 4, 2015   ... announced updated interim data from Tocagen,s ongoing investigational ... Satellite Symposium of the American Association of Neurological ... Tumors, held May 1-2, 2015, in ... the company held a meeting with FDA and ...
(Date:5/4/2015)... 04, 2015 Marianjoy Rehabilitation ... with arm and hand impairments by acquiring the ... Oakbrook Terrace network site. , Secured through grant ... a highly-regarded treatment option for patients with upper ... Marianjoy becomes one of just four Illinois providers ...
(Date:5/1/2015)... MINNEAPOLIS, MN , May 1, 2015 /PRNewswire/ - ... company producing sustainable chemicals, today announced that it has priced ... common stock at a price of $9.00 per share, ... option to purchase up to an additional 585,000 shares ... Company will be $35.1 million.  The offering is expected to ...
Breaking Biology Technology:Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 2Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 3Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 4Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 5Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 6Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 7Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 8Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 9Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 10Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 11Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 12Tocagen Presents Updated Interim Survival Data from Ongoing Clinical Studies at American Association of Neurological Surgeons (AANS)/Congress of Neurological Surgeons (CNS) Section on Tumors 2Tocagen Presents Updated Interim Survival Data from Ongoing Clinical Studies at American Association of Neurological Surgeons (AANS)/Congress of Neurological Surgeons (CNS) Section on Tumors 3Tocagen Presents Updated Interim Survival Data from Ongoing Clinical Studies at American Association of Neurological Surgeons (AANS)/Congress of Neurological Surgeons (CNS) Section on Tumors 4Tocagen Presents Updated Interim Survival Data from Ongoing Clinical Studies at American Association of Neurological Surgeons (AANS)/Congress of Neurological Surgeons (CNS) Section on Tumors 5Marianjoy Acquires Armeo®Spring Arm and Hand Rehabilitation Exoskeleton at Oakbrook Terrace Facility 2BioAmber Inc. Announces Pricing Of $35.1 Million Registered Offering 2BioAmber Inc. Announces Pricing Of $35.1 Million Registered Offering 3
... has released a new medical imaging product for ... reading capabilities of radiologists. , ,According to Merge, the ... make possible simultaneous display and reading of images on ... which vendor's acquisition device is used to secure the ...
... Wis. - GE Healthcare has signed ... Excellence in Breast Cancer Imaging within the University ... ,With funding from GE Healthcare, a $17 billion unit ... designed to advance and commercialize research and technology to ...
... - CIOs must know something that Alan Greenspan doesn't ... mode in the second quarter of 2007, according to the ... hiring. , ,The report, published after former Federal Reserve ... the second half of the year, indicates that 14 percent ...
Cached Biology Technology:
... The MONOLIGHT 3096 Microplate Luminometer ... chemi- and bioluminescence and for,all measurements ... microplates,i.e. for reactions where the light ... of time, as well as for ...
... new Adept CE 4100 high pressure ... flow precision, with software drive compensation, reducing ... 0.001-10mL/min are selectable in 0.001mL steps. , ... inert and bio-compatible., Pumps may be programmed ...
High affinity antibodies recognizes HSP70 protein from human cardiac tissue. Could be used for Westerb blotting application, ELISA....
Recommended for use as a cell culture substratum at 0.1-0.2 mg/cm 2 or 5-10 μl/cm 2 . Optimal concentration depends on cell type as well as the application or research objectives. Type B...
Biology Products: